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HUMAN:UFO
Contents |
| Species (Taxon ID) | Homo sapiens (Human). ([1]) | |
| Gene Name(s) | AXL (synonyms: UFO) | |
| Protein Name(s) | Tyrosine-protein kinase receptor UFO
AXL oncogene | |
| External Links | ||
| EMBL | M76125 S65125 X57019 AC011510 BC032229 | |
| IPI | IPI00296992 IPI00397361 | |
| PIR | A41527 | |
| RefSeq | NP_001690.2 NP_068713.2 | |
| UniGene | Hs.590970 | |
| PDB | 2C5D | |
| PDBsum | 2C5D | |
| ProteinModelPortal | P30530 | |
| SMR | P30530 | |
| IntAct | P30530 | |
| MINT | MINT-2735752 | |
| STRING | P30530 | |
| PhosphoSite | P30530 | |
| PRIDE | P30530 | |
| Ensembl | ENST00000301178 | |
| GeneID | 558 | |
| KEGG | hsa:558 | |
| UCSC | uc010ehj.1 uc010ehk.1 | |
| CTD | 558 | |
| GeneCards | GC19P038157 | |
| HGNC | HGNC:905 | |
| HPA | HPA037422 | |
| MIM | 109135 | |
| neXtProt | NX_P30530 | |
| PharmGKB | PA25197 | |
| eggNOG | prNOG12486 | |
| HOGENOM | HBG444090 | |
| HOVERGEN | HBG006346 | |
| InParanoid | P30530 | |
| OMA | GSLHPHT | |
| OrthoDB | EOG44BB1N | |
| PhylomeDB | P30530 | |
| BRENDA | 2.7.10.1 | |
| ArrayExpress | P30530 | |
| Bgee | P30530 | |
| CleanEx | HS_AXL | |
| Genevestigator | P30530 | |
| GermOnline | ENSG00000167601 | |
| GO | GO:0005887 GO:0005524 GO:0004714 | |
| InterPro | IPR003961 IPR007110 IPR013783 IPR003599 IPR013106 IPR011009 IPR000719 IPR017441 IPR001245 IPR008266 IPR020635 | |
| Gene3D | G3DSA:2.60.40.10 | |
| Pfam | PF00041 PF07714 PF07686 | |
| PRINTS | PR00109 | |
| SMART | SM00060 SM00409 SM00219 | |
| SUPFAM | SSF49265 SSF56112 | |
| PROSITE | PS50853 PS50835 PS00107 PS50011 PS00109 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0001764 |
neuron migration |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000002677 |
P |
Seeded From UniProt |
|||
| GO:0001974 |
blood vessel remodeling |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000002677 |
P |
Seeded From UniProt |
|||
| GO:0004672 |
protein kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004672 |
protein kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004713 |
protein tyrosine kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004713 |
protein tyrosine kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004713 |
protein tyrosine kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004714 |
transmembrane receptor protein tyrosine kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004714 |
transmembrane receptor protein tyrosine kinase activity |
TAS: Traceable Author Statement |
|
F |
Seeded From UniProt |
|||
| GO:0004872 |
receptor activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005886 |
plasma membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005886 |
plasma membrane |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0039 |
C |
Seeded From UniProt |
|||
| GO:0005887 |
integral to plasma membrane |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
|||
| GO:0006468 |
protein phosphorylation |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006468 |
protein phosphorylation |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006468 |
protein phosphorylation |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006954 |
inflammatory response |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000002677 |
P |
Seeded From UniProt |
|||
| GO:0007165 |
signal transduction |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0007167 |
enzyme linked receptor protein signaling pathway |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000002677 |
P |
Seeded From UniProt |
|||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016301 |
kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0016310 |
phosphorylation |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0016740 |
transferase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0016772 |
transferase activity, transferring phosphorus-containing groups |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0021885 |
forebrain cell migration |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000002677 |
P |
Seeded From UniProt |
|||
| GO:0030154 |
cell differentiation |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0030168 |
platelet activation |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000002677 |
P |
Seeded From UniProt |
|||
| GO:0031668 |
cellular response to extracellular stimulus |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000002677 |
P |
Seeded From UniProt |
|||
| GO:0032720 |
negative regulation of tumor necrosis factor production |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000002677 |
P |
Seeded From UniProt |
|||
| GO:0032940 |
secretion by cell |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000002677 |
P |
Seeded From UniProt |
|||
| GO:0034101 |
erythrocyte homeostasis |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000002677 |
P |
Seeded From UniProt |
|||
| GO:0034446 |
substrate adhesion-dependent cell spreading |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000002677 |
P |
Seeded From UniProt |
|||
| GO:0042698 |
ovulation cycle |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000002677 |
P |
Seeded From UniProt |
|||
| GO:0043066 |
negative regulation of apoptosis |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000002677 |
P |
Seeded From UniProt |
|||
| GO:0043277 |
apoptotic cell clearance |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000002677 |
P |
Seeded From UniProt |
|||
| GO:0043491 |
protein kinase B signaling cascade |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000002677 |
P |
Seeded From UniProt |
|||
| GO:0043524 |
negative regulation of neuron apoptosis |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000002677 |
P |
Seeded From UniProt |
|||
| GO:0045087 |
innate immune response |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0046982 |
protein heterodimerization activity |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000002677 |
F |
Seeded From UniProt |
|||
| GO:0044228 |
host cell surface |
IDA: Inferred from Direct Assay |
C |
Fig. 7 and Fig. 8 |
complete | |||
| GO:0046718 |
entry of virus into host cell |
IMP: Inferred from Mutant Phenotype |
P |
Fig. 1 |
complete | |||
| GO:0048549 |
positive regulation of pinocytosis |
IMP: Inferred from Mutant Phenotype |
P |
Fig. 7A |
complete | |||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 O'Bryan JP et al. (1991) axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase. Mol Cell Biol 11: 5016-31 PubMed GONUTS page
- ↑ Brindley MA et al. (2011) Tyrosine kinase receptor Axl enhances entry of Zaire ebolavirus without direct interactions with the viral glycoprotein. Virology 415: 83-94 PubMed GONUTS page
- ↑ 3.0 3.1 Hunt CL et al. (2011) The Tyro3 receptor kinase Axl enhances macropinocytosis of Zaire ebolavirus. J Virol 85: 334-47 PubMed GONUTS page
