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HUMAN:TSG6
Contents |
| Species (Taxon ID) | Homo sapiens (Human). ([1]) | |
| Gene Name(s) | TNFAIP6 (synonyms: TSG6) | |
| Protein Name(s) | Tumor necrosis factor-inducible gene 6 protein
Hyaluronate-binding protein TNF-stimulated gene 6 protein TSG-6 Tumor necrosis factor alpha-induced protein 6 TNF alpha-induced protein 6 | |
| External Links | ||
| EMBL | M31165 AJ421518 AJ419936 AC009311 CH471058 BC030205 | |
| IPI | IPI00303341 | |
| PIR | A41735 | |
| RefSeq | NP_009046.2 | |
| UniGene | Hs.437322 | |
| PDB | 1O7B 1O7C 2PF5 2WNO | |
| PDBsum | 1O7B 1O7C 2PF5 2WNO | |
| ProteinModelPortal | P98066 | |
| SMR | P98066 | |
| STRING | P98066 | |
| PhosphoSite | P98066 | |
| PRIDE | P98066 | |
| Ensembl | ENST00000243347 | |
| GeneID | 7130 | |
| KEGG | hsa:7130 | |
| UCSC | uc002txk.1 | |
| CTD | 7130 | |
| GeneCards | GC02P144110 | |
| H-InvDB | HIX0018802 | |
| HGNC | HGNC:11898 | |
| HPA | CAB032719 | |
| MIM | 600410 | |
| neXtProt | NX_P98066 | |
| PharmGKB | PA36595 | |
| eggNOG | prNOG05017 | |
| GeneTree | ENSGT00600000084297 | |
| HOGENOM | HBG281495 | |
| HOVERGEN | HBG006669 | |
| InParanoid | P98066 | |
| OMA | AKAVCEY | |
| OrthoDB | EOG4WWRK3 | |
| PhylomeDB | P98066 | |
| NextBio | 27899 | |
| ArrayExpress | P98066 | |
| Bgee | P98066 | |
| CleanEx | HS_TNFAIP6 | |
| Genevestigator | P98066 | |
| GermOnline | ENSG00000123610 | |
| GO | GO:0005540 GO:0007155 GO:0007267 GO:0006954 GO:0007165 | |
| InterPro | IPR016186 IPR016187 IPR000859 IPR000538 | |
| Gene3D | G3DSA:3.10.100.10 G3DSA:2.60.120.290 | |
| Pfam | PF00431 PF00193 | |
| PRINTS | PR01265 | |
| SMART | SM00042 SM00445 | |
| SUPFAM | SSF56436 SSF49854 | |
| PROSITE | PS01180 PS01241 PS50963 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005488 |
binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005488 |
binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005540 |
hyaluronic acid binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005540 |
hyaluronic acid binding |
TAS: Traceable Author Statement |
|
F |
Seeded From UniProt |
|||
| GO:0006954 |
inflammatory response |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0007155 |
cell adhesion |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007155 |
cell adhesion |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007165 |
signal transduction |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0007267 |
cell-cell signaling |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0050728 |
negative regulation of inflammatory response |
IDA: Inferred from Direct Assay |
P |
Fig.7 |
complete | |||
| GO:0003674 |
molecular function |
IDA: Inferred from Direct Assay |
F |
Fig.2 Fig.4 |
complete | |||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Lee TH et al. (1992) A novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44. J Cell Biol 116: 545-57 PubMed GONUTS page
- ↑ Danchuk S et al. (2011) Human multipotent stromal cells attenuate lipopolysaccharide-induced acute lung injury in mice via secretion of tumor necrosis factor-α-induced protein 6. Stem Cell Res Ther 2: 27 PubMed GONUTS page
- ↑ Baranova NS et al. (2011) The inflammation-associated protein TSG-6 cross-links hyaluronan via hyaluronan-induced TSG-6 oligomers. J Biol Chem 286: 25675-86 PubMed GONUTS page
