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HUMAN:TRFE
Contents |
| Species (Taxon ID) | Homo sapiens (Human). ([1]) | |
| Gene Name(s) | TF | |
| Protein Name(s) | Serotransferrin
Transferrin Beta-1 metal-binding globulin Siderophilin | |
| External Links | ||
| EMBL | M12530 M17611 M17610 M17614 M17612 M17613 S95936 AF288144 AF294270 AF294271 AF288139 AF288140 AF288141 AF288142 AF288143 AY308797 DQ525716 AC080128 AC083905 CH471052 BC059367 M21569 M15673 M21570 X04600 AJ252279 M11372 M11361 M11362 M11363 M11364 M11365 M11366 M11367 M11368 M11369 M11370 M11371 AF118063 M12525 U88581 AF058327 M26641 | |
| IPI | IPI00022463 | |
| PIR | A20981 | |
| RefSeq | NP_001054.1 | |
| UniGene | Hs.518267 Hs.729019 | |
| PDB | 1A8E 1A8F 1B3E 1BP5 1BTJ 1D3K 1D4N 1DTG 1FQE 1FQF 1JQF 1N7W 1N7X 1N84 1OQG 1OQH 1RYO 1SUV 2HAU 2HAV 2O7U 2O84 3FGS 3S9L 3S9M 3S9N | |
| PDBsum | 1A8E 1A8F 1B3E 1BP5 1BTJ 1D3K 1D4N 1DTG 1FQE 1FQF 1JQF 1N7W 1N7X 1N84 1OQG 1OQH 1RYO 1SUV 2HAU 2HAV 2O7U 2O84 3FGS 3S9L 3S9M 3S9N | |
| ProteinModelPortal | P02787 | |
| SMR | P02787 | |
| DIP | DIP-2738N | |
| IntAct | P02787 | |
| MINT | MINT-1400694 | |
| STRING | P02787 | |
| MEROPS | S60.972 S60.975 | |
| GlycoSuiteDB | P02787 | |
| PhosphoSite | P02787 | |
| SWISS-2DPAGE | P02787 | |
| Cornea-2DPAGE | P02787 | |
| DOSAC-COBS-2DPAGE | P02787 | |
| REPRODUCTION-2DPAGE | IPI00022463 P02787 | |
| Siena-2DPAGE | P02787 | |
| UCD-2DPAGE | P02787 | |
| PRIDE | P02787 | |
| Ensembl | ENST00000264998 ENST00000402696 | |
| GeneID | 7018 | |
| KEGG | hsa:7018 | |
| UCSC | uc003epv.1 | |
| CTD | 7018 | |
| GeneCards | GC03P130844 | |
| H-InvDB | HIX0024281 | |
| HGNC | HGNC:11740 | |
| HPA | CAB009538 HPA001527 HPA005692 | |
| MIM | 190000 209300 | |
| neXtProt | NX_P02787 | |
| Orphanet | 1195 | |
| HOGENOM | HBG714005 | |
| HOVERGEN | HBG000055 | |
| InParanoid | P02787 | |
| OMA | AETTEDC | |
| OrthoDB | EOG4CRKZG | |
| Pathway_Interaction_DB | ephbfwdpathway hif1_tfpathway | |
| Reactome | REACT_15518 REACT_604 | |
| DrugBank | DB01370 DB01402 DB00893 | |
| NextBio | 27415 | |
| PMAP-CutDB | P02787 | |
| ArrayExpress | P02787 | |
| Bgee | P02787 | |
| CleanEx | HS_TF | |
| Genevestigator | P02787 | |
| GermOnline | ENSG00000091513 | |
| GO | GO:0016324 GO:0009925 GO:0005905 GO:0005769 GO:0030139 GO:0010008 GO:0005576 GO:0005770 GO:0048471 GO:0055037 GO:0030141 GO:0008199 GO:0006879 GO:0030168 GO:0002576 GO:0033572 GO:0055085 | |
| InterPro | IPR001156 IPR016357 IPR018195 | |
| PANTHER | PTHR11485 | |
| Pfam | PF00405 | |
| PIRSF | PIRSF002549 | |
| PRINTS | PR00422 | |
| SMART | SM00094 | |
| PROSITE | PS00205 PS00206 PS00207 PS51408 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0002576 |
platelet degranulation |
Reactome:REACT_318 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded From UniProt |
||||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded From UniProt |
||||
| GO:0005576 |
extracellular region |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005576 |
extracellular region |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005576 |
extracellular region |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005576 |
extracellular region |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0243 |
C |
Seeded From UniProt |
|||
| GO:0005576 |
extracellular region |
NAS: Non-traceable Author Statement |
|
C |
Seeded From UniProt |
|||
| GO:0005576 |
extracellular region |
Reactome:REACT_21324 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0005576 |
extracellular region |
Reactome:REACT_24927 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0005576 |
extracellular region |
Reactome:REACT_24945 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0005576 |
extracellular region |
Reactome:REACT_24977 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0005576 |
extracellular region |
Reactome:REACT_25385 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0005576 |
extracellular region |
Reactome:REACT_25389 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0005769 |
early endosome |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0005770 |
late endosome |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0005905 |
coated pit |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0006810 |
transport |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006811 |
ion transport |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006826 |
iron ion transport |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006826 |
iron ion transport |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006879 |
cellular iron ion homeostasis |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006879 |
cellular iron ion homeostasis |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006879 |
cellular iron ion homeostasis |
Reactome:REACT_25060 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0007596 |
blood coagulation |
Reactome:REACT_604 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0008199 |
ferric iron binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0008199 |
ferric iron binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0009925 |
basal plasma membrane |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0010008 |
endosome membrane |
Reactome:REACT_24977 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0010008 |
endosome membrane |
Reactome:REACT_25277 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0010008 |
endosome membrane |
Reactome:REACT_25389 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0016023 |
cytoplasmic membrane-bounded vesicle |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0016324 |
apical plasma membrane |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0030139 |
endocytic vesicle |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0030139 |
endocytic vesicle |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0030141 |
stored secretory granule |
Reactome:REACT_21324 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0030168 |
platelet activation |
Reactome:REACT_798 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0031625 |
ubiquitin protein ligase binding |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000012725 |
F |
Seeded From UniProt |
|||
| GO:0033572 |
transferrin transport |
Reactome:REACT_25283 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0045178 |
basal part of cell |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0046872 |
metal ion binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0048471 |
perinuclear region of cytoplasm |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0055037 |
recycling endosome |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0055072 |
iron ion homeostasis |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0055085 |
transmembrane transport |
Reactome:REACT_15518 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0048471 |
perinuclear region of cytoplasm |
IDA: Inferred from Direct Assay |
C |
Fig. 2B |
complete | |||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Gruper Y et al. (2005) Transferrin receptor co-localizes and interacts with the hemochromatosis factor (HFE) and the divalent metal transporter-1 (DMT1) in trophoblast cells. J Cell Physiol 204: 901-12 PubMed GONUTS page
- ↑ Anderson NL et al. (2004) The human plasma proteome: a nonredundant list developed by combination of four separate sources. Mol Cell Proteomics 3: 311-26 PubMed GONUTS page
- ↑ 3.0 3.1 Aschenbrenner L et al. (2003) Myo6 facilitates the translocation of endocytic vesicles from cell peripheries. Mol Biol Cell 14: 2728-43 PubMed GONUTS page
- ↑ Durrbach A et al. (2000) Truncated brush border myosin I affects membrane traffic in polarized epithelial cells. Traffic 1: 411-24 PubMed GONUTS page
- ↑ Coumailleau F et al. (2004) Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment. Mol Biol Cell 15: 4444-56 PubMed GONUTS page
- ↑ Simonsen A et al. (2004) Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes. J Cell Sci 117: 4239-51 PubMed GONUTS page
- ↑ Bhattacharyya S et al. (2010) Ebola virus uses clathrin-mediated endocytosis as an entry pathway. Virology 401: 18-28 PubMed GONUTS page
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