HUMAN:TF2L1

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Species (Taxon ID)	Homo sapiens (Human). (taxon:9606)
Gene Name(s)	TFCP2L1 ( synonyms: CRTR1, LBP9 )
Protein Name(s)	Transcription factor CP2-like protein 1 CP2-related transcriptional repressor 1 CRTR-1 Transcription factor LBP-9
External Links
UniProt Identifier	TF2L1_HUMAN
UniProt Accessions	Q9NZI6, Q4ZG43,
EMBL	AF198488, AC013399, AC079988, BC064698,
RefSeq	NP_055368.1,
Ensembl	ENST00000263707,
Pfam	PF04516,

Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes	Status
	GO:0005634	nucleus	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0191	C
	GO:0000122	negative regulation of transcription from RNA polymerase II promoter	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000027629	P
	GO:0005737	cytoplasm	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000027629	C
	GO:0045927	positive regulation of growth	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000027629	P
	GO:0006350	transcription	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0804	P
	GO:0005730	nucleolus	PMID:18029348^[1]	IDA: Inferred from Direct Assay		C
	GO:0003714	transcription corepressor activity	PMID:10644752^[2]	TAS: Traceable Author Statement		F
	GO:0005634	nucleus	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000027629	C
	GO:0003677	DNA binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0238	F
	GO:0006351	transcription, DNA-dependent	PMID:10644752^[2]	TAS: Traceable Author Statement		P
	GO:0007431	salivary gland development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000027629	P
	GO:0006694	steroid biosynthetic process	PMID:10644752^[2]	TAS: Traceable Author Statement		P
	GO:0006357	regulation of transcription from RNA polymerase II promoter	PMID:10644752^[2]	TAS: Traceable Author Statement		P
	GO:0016481	negative regulation of transcription	PMID:10644752^[2]	TAS: Traceable Author Statement		P
	GO:0000902	cell morphogenesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000027629	P
	GO:0003700	sequence-specific DNA binding transcription factor activity	PMID:10644752^[2]	TAS: Traceable Author Statement		F
	GO:0002070	epithelial cell maturation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000027629	P
	GO:0007028	cytoplasm organization	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000027629	P
	GO:0016565	general transcriptional repressor activity	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000027629	F
	GO:0005634	nucleus	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0539	C
	GO:0007565	female pregnancy	PMID:10644752^[2]	TAS: Traceable Author Statement		P
	GO:0045449	regulation of transcription	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0805	P
	GO:0008340	determination of adult lifespan	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000027629	P
	GO:0016020	membrane	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000027629	C
	GO:0005739	mitochondrion	PMID:18029348^[1]	IDA: Inferred from Direct Assay		C
	GO:0016563	transcription activator activity	PMID:20661472^[3]	IDA: Inferred from Direct Assay		F	Figure 1A	complete
	GO:0000122	negative regulation of transcription from RNA polymerase II promoter	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000027629	P
	GO:0000902	cell morphogenesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000027629	P
	GO:0002070	epithelial cell maturation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000027629	P
	GO:0003677	DNA binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0238	F
	GO:0003700	sequence-specific DNA binding transcription factor activity	PMID:10644752^[2]	TAS: Traceable Author Statement		F
	GO:0003714	transcription corepressor activity	PMID:10644752^[2]	TAS: Traceable Author Statement		F
	GO:0005634	nucleus	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0539	C
	GO:0005634	nucleus	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000027629	C
	GO:0005634	nucleus	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0191	C
	GO:0005730	nucleolus	PMID:18029348^[1]	IDA: Inferred from Direct Assay		C
	GO:0005737	cytoplasm	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000027629	C
	GO:0005739	mitochondrion	PMID:18029348^[1]	IDA: Inferred from Direct Assay		C
	GO:0006351	transcription, DNA-dependent	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0804	P
	GO:0006351	transcription, DNA-dependent	PMID:10644752^[2]	TAS: Traceable Author Statement		P
	GO:0006355	regulation of transcription, DNA-dependent	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0805	P
	GO:0006357	regulation of transcription from RNA polymerase II promoter	PMID:10644752^[2]	TAS: Traceable Author Statement		P
	GO:0006694	steroid biosynthetic process	PMID:10644752^[2]	TAS: Traceable Author Statement		P
	GO:0007028	cytoplasm organization	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000027629	P
	GO:0007431	salivary gland development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000027629	P
	GO:0007565	female pregnancy	PMID:10644752^[2]	TAS: Traceable Author Statement		P
	GO:0008340	determination of adult lifespan	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000027629	P
	GO:0016020	membrane	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000027629	C
	GO:0045927	positive regulation of growth	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000027629	P
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Barbe L et al. (2008) Toward a confocal subcellular atlas of the human proteome. Mol Cell Proteomics 7: 499-508 PubMed GONUTS page
↑ ^2.00 ^2.01 ^2.02 ^2.03 ^2.04 ^2.05 ^2.06 ^2.07 ^2.08 ^2.09 ^2.10 ^2.11 ^2.12 Huang N & Miller WL (2000) Cloning of factors related to HIV-inducible LBP proteins that regulate steroidogenic factor-1-independent human placental transcription of the cholesterol side-chain cleavage enzyme, P450scc. J Biol Chem 275: 2852-8 PubMed GONUTS page
↑ To S et al. (2010) Modulation of CP2 family transcriptional activity by CRTR-1 and sumoylation. PLoS One 5: e11702 PubMed GONUTS page

[PMID:18029348-0] 1.0 ^1.1 ^1.2 ^1.3 Barbe L et al. (2008) Toward a confocal subcellular atlas of the human proteome. Mol Cell Proteomics 7: 499-508 PubMed GONUTS page

[PMID:10644752-1] 2.00 ^2.01 ^2.02 ^2.03 ^2.04 ^2.05 ^2.06 ^2.07 ^2.08 ^2.09 ^2.10 ^2.11 ^2.12 Huang N & Miller WL (2000) Cloning of factors related to HIV-inducible LBP proteins that regulate steroidogenic factor-1-independent human placental transcription of the cholesterol side-chain cleavage enzyme, P450scc. J Biol Chem 275: 2852-8 PubMed GONUTS page

[PMID:20661472-2] To S et al. (2010) Modulation of CP2 family transcriptional activity by CRTR-1 and sumoylation. PLoS One 5: e11702 PubMed GONUTS page

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HUMAN:TF2L1

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