Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

HUMAN:SP2

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Homo sapiens (Human). (taxon:9606)
Gene Name(s) SP2 ( synonyms: KIAA0048 )
Protein Name(s)
  • Transcription factor Sp2
External Links
UniProt Identifier SP2_HUMAN
UniProt Accessions Q02086, A6NK74,
EMBL D28588, AC018521, CH471109, BC016680, BC033814, M97190,
PIR A44489,
RefSeq NP_003101.3,
Ensembl ENST00000376741,
Pfam PF00096,

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005634

nucleus

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0539

C

GO:0005634

nucleus

PMID:18029348[1]

IDA: Inferred from Direct Assay

C

GO:0042826

histone deacetylase binding

PMID:17827154[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q92769

F

GO:0003677

DNA binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0238

F

GO:0003676

nucleic acid binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013087

F

GO:0045449

regulation of transcription

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0805

P

GO:0008270

zinc ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015880

F

GO:0006357

regulation of transcription from RNA polymerase II promoter

PMID:1341900[3]

TAS: Traceable Author Statement

P

GO:0046872

metal ion binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0479

F

GO:0003702

RNA polymerase II transcription factor activity

PMID:1341900[3]

TAS: Traceable Author Statement

F

GO:0005622

intracellular

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR007087

C

GO:0006955

immune response

PMID:1341900[3]

TAS: Traceable Author Statement

P

GO:0008270

zinc ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR007087

F

GO:0005634

nucleus

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0191

C

GO:0006350

transcription

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0804

P

GO:0005622

intracellular

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015880

C

GO:0016363

nuclear matrix

PMID:16467376[4]

IDA: Inferred from Direct Assay

C

Figure 5B shows that sp2 is associated with the nuclear matrix

complete

GO:0003676

nucleic acid binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013087

F

GO:0003677

DNA binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0238

F

GO:0005622

intracellular

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR007087

C

GO:0005622

intracellular

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015880

C

GO:0005634

nucleus

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0539

C

GO:0005634

nucleus

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0191

C

GO:0005634

nucleus

PMID:18029348[1]

IDA: Inferred from Direct Assay

C

GO:0006351

transcription, DNA-dependent

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0804

P

GO:0006355

regulation of transcription, DNA-dependent

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0805

P

GO:0006357

regulation of transcription from RNA polymerase II promoter

PMID:1341900[3]

TAS: Traceable Author Statement

P

GO:0006955

immune response

PMID:1341900[3]

TAS: Traceable Author Statement

P

GO:0008270

zinc ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR007087

F

GO:0008270

zinc ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015880

F

GO:0042826

histone deacetylase binding

PMID:17827154[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q92769

F

GO:0046872

metal ion binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0479

F


Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Barbe L et al. (2008) Toward a confocal subcellular atlas of the human proteome. Mol Cell Proteomics 7: 499-508 PubMed GONUTS page
  2. 2.0 2.1 Sun JM et al. (2007) Differential distribution of unmodified and phosphorylated histone deacetylase 2 in chromatin. J Biol Chem 282: 33227-36 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 Kingsley C & Winoto A (1992) Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression. Mol Cell Biol 12: 4251-61 PubMed GONUTS page
  4. Moorefield KS et al. (2006) Sp2 localizes to subnuclear foci associated with the nuclear matrix. Mol Biol Cell 17: 1711-22 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox