GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
HUMAN:SMAD9
Contents
Species (Taxon ID) | Homo sapiens (Human). (9606) | |
Gene Name(s) | SMAD9 (synonyms: MADH6, MADH9) | |
Protein Name(s) | Mothers against decapentaplegic homolog 9
MAD homolog 9 Mothers against DPP homolog 9 Madh6 SMAD family member 9 SMAD 9 Smad9 | |
External Links | ||
UniProt | O15198 | |
EMBL | D83760 D83761 AL138706 AL138706 CH471075 CH471075 BC011559 BC104760 BC104762 BC143240 | |
CCDS | CCDS45032.1 CCDS9360.1 | |
RefSeq | NP_001120689.1 NP_005896.1 | |
UniGene | Hs.123119 | |
ProteinModelPortal | O15198 | |
SMR | O15198 | |
BioGrid | 110268 | |
IntAct | O15198 | |
MINT | MINT-1179670 | |
STRING | 9606.ENSP00000369154 | |
PhosphoSite | O15198 | |
BioMuta | SMAD9 | |
MaxQB | O15198 | |
PaxDb | O15198 | |
PRIDE | O15198 | |
DNASU | 4093 | |
Ensembl | ENST00000379826 ENST00000399275 | |
GeneID | 4093 | |
KEGG | hsa:4093 | |
UCSC | uc001uvw.3 uc001uvx.3 | |
CTD | 4093 | |
GeneCards | GC13M037418 | |
HGNC | HGNC:6774 | |
HPA | CAB009119 HPA031162 | |
MIM | 603295 615342 | |
neXtProt | NX_O15198 | |
Orphanet | 275777 | |
PharmGKB | PA30531 | |
eggNOG | NOG330956 | |
GeneTree | ENSGT00760000119091 | |
HOGENOM | HOG000286018 | |
HOVERGEN | HBG053353 | |
InParanoid | O15198 | |
KO | K16791 | |
OMA | FQQPPCP | |
OrthoDB | EOG7W1540 | |
PhylomeDB | O15198 | |
TreeFam | TF314923 | |
Reactome | REACT_12034 | |
ChiTaRS | SMAD9 | |
GeneWiki | Mothers_against_decapentaplegic_homolog_9 | |
GenomeRNAi | 4093 | |
NextBio | 16050 | |
PRO | PR:O15198 | |
Proteomes | UP000005640 | |
Bgee | O15198 | |
CleanEx | HS_SMAD9 | |
ExpressionAtlas | O15198 | |
Genevisible | O15198 | |
GO | GO:0005737 GO:0005829 GO:0005622 GO:0005654 GO:0005634 GO:0005667 GO:0003677 GO:0046872 GO:0003700 GO:0030618 GO:0030509 GO:0060348 GO:0051216 GO:0071407 GO:0030902 GO:0035556 GO:0030901 GO:0006468 GO:0006351 GO:0007179 GO:0001657 | |
Gene3D | 2.60.200.10 3.90.520.10 | |
InterPro | IPR013790 IPR003619 IPR013019 IPR017855 IPR001132 IPR008984 | |
PANTHER | PTHR13703 | |
Pfam | PF03165 PF03166 | |
SMART | SM00523 SM00524 | |
SUPFAM | SSF49879 SSF56366 | |
PROSITE | PS51075 PS51076 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
enables |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ECO:0000303 |
author statement without traceable support used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ECO:0000255 |
match to sequence model evidence used in manual assertion |
InterPro:IPR001132 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
part_of:(UBERON:0002107) |
Seeded From UniProt |
complete | ||
part_of |
GO:0005634 |
nucleus |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
part_of:(UBERON:0002107) |
Seeded From UniProt |
complete | ||
involved_in |
GO:0060395 |
SMAD protein signal transduction |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
|
Seeded From UniProt |
complete | ||
involved_in |
GO:0030509 |
BMP signaling pathway |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
occurs_in:(UBERON:0002107) |
Seeded From UniProt |
complete | ||
involved_in |
GO:0071773 |
cellular response to BMP stimulus |
ECO:0000303 |
author statement without traceable support used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0071141 |
SMAD protein complex |
ECO:0000303 |
author statement without traceable support used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0060395 |
SMAD protein signal transduction |
ECO:0000303 |
author statement without traceable support used in manual assertion |
P |
part_of:(GO:0071773) |
Seeded From UniProt |
complete | ||
enables |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ECO:0005556 |
multiple sequence alignment evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005654 |
nucleoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005667 |
transcription factor complex |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001132 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007179 |
transforming growth factor beta receptor signaling pathway |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:1901522 |
positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
part_of:(GO:0071773) |
Seeded From UniProt |
complete | ||
part_of |
GO:0005622 |
intracellular |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0030618 |
transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030509 |
BMP signaling pathway |
PMID:19018011[4] |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
P |
Seeded From UniProt |
complete | |
part_of |
GO:0005634 |
nucleus |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005829 |
cytosol |
Reactome:R-HSA-202626 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
part_of |
GO:0005654 |
nucleoplasm |
Reactome:R-HSA-201472 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Vaquerizas, JM et al. (2009) A census of human transcription factors: function, expression and evolution. Nat. Rev. Genet. 10 252-63 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Nohe, A et al. (2004) Signal transduction of bone morphogenetic protein receptors. Cell. Signal. 16 291-9 PubMed GONUTS page
- ↑ Topper, JN et al. (1997) Vascular MADs: two novel MAD-related genes selectively inducible by flow in human vascular endothelium. Proc. Natl. Acad. Sci. U.S.A. 94 9314-9 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Hoover, LL & Kubalak, SW (2008) Holding their own: the noncanonical roles of Smad proteins. Sci Signal 1 pe48 PubMed GONUTS page
c
d
o
p
t