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HUMAN:SHAN2

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Contents

Species (Taxon ID) Homo sapiens (Human). (taxon:9606)
Gene Name(s) SHANK2 ( synonyms: CORTBP1, KIAA1022, PROSAP1 )
Protein Name(s)
  • SH3 and multiple ankyrin repeat domains protein 2
  • Shank2
  • Cortactin-binding protein 1
  • CortBP1
  • Proline-rich synapse-associated protein 1
External Links
UniProt Identifier SHAN2_HUMAN
UniProt Accessions Q9UPX8, C0SPG8, C0SPG9, Q3Y8G9, Q52LK2, Q9UKP1,
EMBL AB208025, AB208026, AP000590, AP001271, AP003783, AP005401, BC093885, BC112097, DQ152234, AB028945, AF141901,
RefSeq NP_036441.2,
IntAct Q9UPX8,
Ensembl ENST00000433693,
Pfam PF00595, PF00536, PF07653,

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005515

protein binding

PMID:11583995[1]

IPI: Inferred from Physical Interaction

UniProtKB:P50570

F

GO:0005515

protein binding

PMID:17474147[2]

IPI: Inferred from Physical Interaction

UniProtKB:P12931

F

GO:0005515

protein binding

PMID:17474147[2]

IPI: Inferred from Physical Interaction

UniProtKB:P16333

F

GO:0005515

protein binding

PMID:17474147[2]

IPI: Inferred from Physical Interaction

UniProtKB:P19174

F

GO:0005515

protein binding

PMID:17474147[2]

IPI: Inferred from Physical Interaction

UniProtKB:P27986

F

GO:0005515

protein binding

PMID:17474147[2]

IPI: Inferred from Physical Interaction

UniProtKB:P46108

F

GO:0005515

protein binding

PMID:17474147[2]

IPI: Inferred from Physical Interaction

UniProtKB:P62993

F

GO:0005575

cellular component

GO_REF:0000015

ND: No biological Data available

C

GO:0005737

cytoplasm

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

GO:0005886

plasma membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

GO:0014069

postsynaptic density

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0297

C

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

GO:0017124

SH3 domain binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0729

F

GO:0030054

cell junction

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0965

C

GO:0030160

GKAP/Homer scaffold activity

PMID:10506216[3]

NAS: Non-traceable Author Statement

F

GO:0035255

ionotropic glutamate receptor binding

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q80Z38

F

GO:0035556

intracellular signal transduction

GO_REF:0000029

NAS: Non-traceable Author Statement

P

GO:0045202

synapse

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0770

C

GO:0045202

synapse

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0258

C

GO:0045211

postsynaptic membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0628

C

GO:0005515

protein binding

PMID:11583995[1]

IPI: Inferred from Physical Interaction

UniProtKB:P50570

F

GO:0005515

protein binding

PMID:17474147[2]

IPI: Inferred from Physical Interaction

UniProtKB:P12931

F

GO:0005515

protein binding

PMID:17474147[2]

IPI: Inferred from Physical Interaction

UniProtKB:P16333

F

GO:0005515

protein binding

PMID:17474147[2]

IPI: Inferred from Physical Interaction

UniProtKB:P19174

F

GO:0005515

protein binding

PMID:17474147[2]

IPI: Inferred from Physical Interaction

UniProtKB:P27986

F

GO:0005515

protein binding

PMID:17474147[2]

IPI: Inferred from Physical Interaction

UniProtKB:P46108

F

GO:0005515

protein binding

PMID:17474147[2]

IPI: Inferred from Physical Interaction

UniProtKB:P62993

F

GO:0005575

cellular component

GO_REF:0000015

ND: No biological Data available

C

GO:0005622

intracellular

GO_REF:0000029

NAS: Non-traceable Author Statement

C

GO:0005737

cytoplasm

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

GO:0005886

plasma membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

GO:0014069

postsynaptic density

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0297

C

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

GO:0017124

SH3 domain binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0729

F

GO:0030054

cell junction

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0965

C

GO:0030160

GKAP/Homer scaffold activity

PMID:10506216[3]

NAS: Non-traceable Author Statement

F

GO:0035255

ionotropic glutamate receptor binding

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q80Z38

F

GO:0035556

intracellular signal transduction

GO_REF:0000029

NAS: Non-traceable Author Statement

P

GO:0045202

synapse

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0770

C

GO:0045202

synapse

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0258

C

GO:0045211

postsynaptic membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0628

C


Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Okamoto PM et al. (2001) Dynamin isoform-specific interaction with the shank/ProSAP scaffolding proteins of the postsynaptic density and actin cytoskeleton. J Biol Chem 276: 48458-65 PubMed GONUTS page
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 Wu C et al. (2007) Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. Proteomics 7: 1775-85 PubMed GONUTS page
  3. 3.0 3.1 Lim S et al. (1999) Characterization of the Shank family of synaptic proteins. Multiple genes, alternative splicing, and differential expression in brain and development. J Biol Chem 274: 29510-8 PubMed GONUTS page
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