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HUMAN:RGRF2
Contents |
| Species (Taxon ID) | Homo sapiens (Human). ([1]) | |
| Gene Name(s) | RASGRF2 (synonyms: GRF2) | |
| Protein Name(s) | Ras-specific guanine nucleotide-releasing factor 2
Ras-GRF2 Ras guanine nucleotide exchange factor 2 | |
| External Links | ||
| EMBL | AF023130 AF181250 CH471084 BC126112 BC136296 | |
| IPI | IPI00024184 | |
| RefSeq | NP_008840.1 | |
| UniGene | Hs.162129 | |
| ProteinModelPortal | O14827 | |
| SMR | O14827 | |
| IntAct | O14827 | |
| STRING | O14827 | |
| PhosphoSite | O14827 | |
| PRIDE | O14827 | |
| Ensembl | ENST00000265080 | |
| GeneID | 5924 | |
| KEGG | hsa:5924 | |
| UCSC | uc003kha.1 | |
| CTD | 5924 | |
| GeneCards | GC05P075465 | |
| H-InvDB | HIX0004997 | |
| HGNC | HGNC:9876 | |
| HPA | HPA018679 | |
| MIM | 606614 | |
| neXtProt | NX_O14827 | |
| PharmGKB | PA34239 | |
| HOGENOM | HBG443647 | |
| HOVERGEN | HBG005208 | |
| InParanoid | O14827 | |
| OMA | MSDISQC | |
| OrthoDB | EOG4W6NV6 | |
| PhylomeDB | O14827 | |
| Reactome | REACT_111102 REACT_13685 | |
| NextBio | 23072 | |
| Bgee | O14827 | |
| CleanEx | HS_RASGRF2 | |
| Genevestigator | O14827 | |
| GO | GO:0005829 GO:0005789 GO:0005886 GO:0005089 GO:0006915 GO:0008624 GO:0048011 GO:0035023 GO:0007264 GO:0007268 | |
| InterPro | IPR000219 IPR000048 IPR011993 IPR001849 IPR000651 IPR019804 IPR008937 IPR023578 IPR001895 | |
| Gene3D | G3DSA:2.30.29.30 G3DSA:1.10.840.10 G3DSA:1.20.900.10 | |
| KO | K12326 | |
| PANTHER | PTHR23113 | |
| Pfam | PF00169 PF00617 PF00618 PF00621 | |
| SMART | SM00015 SM00233 SM00147 SM00229 SM00325 | |
| SUPFAM | SSF48065 SSF48366 | |
| PROSITE | PS00741 PS50010 PS50096 PS50003 PS00720 PS50009 PS50212 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005085 |
guanyl-nucleotide exchange factor activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005085 |
guanyl-nucleotide exchange factor activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005085 |
guanyl-nucleotide exchange factor activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005085 |
guanyl-nucleotide exchange factor activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005085 |
guanyl-nucleotide exchange factor activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005089 |
Rho guanyl-nucleotide exchange factor activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005622 |
intracellular |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005622 |
intracellular |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005622 |
intracellular |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005622 |
intracellular |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0086 |
C |
Seeded From UniProt |
|||
| GO:0005737 |
cytoplasm |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0005783 |
endoplasmic reticulum |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005789 |
endoplasmic reticulum membrane |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0097 |
C |
Seeded From UniProt |
|||
| GO:0005829 |
cytosol |
Reactome:REACT_10098 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0005829 |
cytosol |
Reactome:REACT_13694 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0005829 |
cytosol |
Reactome:REACT_19216 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0005886 |
plasma membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005886 |
plasma membrane |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0039 |
C |
Seeded From UniProt |
|||
| GO:0005886 |
plasma membrane |
Reactome:REACT_20612 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0005886 |
plasma membrane |
Reactome:REACT_20670 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0006915 |
apoptosis |
Reactome:REACT_13638 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0007264 |
small GTPase mediated signal transduction |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007264 |
small GTPase mediated signal transduction |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007264 |
small GTPase mediated signal transduction |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007264 |
small GTPase mediated signal transduction |
Reactome:REACT_11044 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0007268 |
synaptic transmission |
Reactome:REACT_13477 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0007268 |
synaptic transmission |
Reactome:REACT_13685 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0008624 |
induction of apoptosis by extracellular signals |
Reactome:REACT_13720 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0035023 |
regulation of Rho protein signal transduction |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0048011 |
nerve growth factor receptor signaling pathway |
Reactome:REACT_11061 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0048011 |
nerve growth factor receptor signaling pathway |
Reactome:REACT_13776 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0051056 |
regulation of small GTPase mediated signal transduction |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0051056 |
regulation of small GTPase mediated signal transduction |
Reactome:REACT_11051 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Barbe L et al. (2008) Toward a confocal subcellular atlas of the human proteome. Mol Cell Proteomics 7: 499-508 PubMed GONUTS page
