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HUMAN:RASN

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Contents

Species (Taxon ID) Homo sapiens (Human). ([1])
Gene Name(s) NRAS (synonyms: HRAS1)
Protein Name(s) GTPase NRas

Transforming protein N-Ras

External Links
EMBL X02751
X00642
X00643
X00644
X00645
L00043
L00040
L00041
L00042
AF493919
AY428630
BC005219
M25898
X53291
X53292
K03211
M10055
X05565
X07440
IPI IPI00000005
PIR A90839
I38149
RefSeq NP_002515.1
UniGene Hs.486502
PDB 3CON
PDBsum 3CON
ProteinModelPortal P01111
SMR P01111
DIP DIP-1058N
IntAct P01111
MINT MINT-131535
STRING P01111
PhosphoSite P01111
OGP P01111
PeptideAtlas P01111
PRIDE P01111
Ensembl ENST00000369535
GeneID 4893
KEGG hsa:4893
UCSC uc009wgu.1
CTD 4893
GeneCards GC01M113105
HGNC HGNC:7989
HPA CAB010157
MIM 164790
607785
613224
neXtProt NX_P01111
Orphanet 3261
648
PharmGKB PA31768
HOGENOM HBG745225
HOVERGEN HBG009351
InParanoid P01111
OMA DIGTYRE
OrthoDB EOG4BRWMX
PhylomeDB P01111
Pathway_Interaction_DB pi3kcipathway
cd8tcrdownstreampathway
ephbfwdpathway
il2_1pathway
trkrpathway
er_nongenomic_pathway
tcrraspathway
tcrpathway
cd8tcrpathway
pi3kplctrkpathway
mapktrkpathway
Reactome REACT_11061
REACT_16888
REACT_18266
REACT_498
REACT_604
REACT_6900
REACT_9417
NextBio 18835
ArrayExpress P01111
Bgee P01111
CleanEx HS_NRAS
Genevestigator P01111
GermOnline ENSG00000009307
GO GO:0000139
GO:0005886
GO:0005525
GO:0003924
GO:0000186
GO:0007411
GO:0007596
GO:0007173
GO:0008286
GO:0050900
GO:0048011
GO:0007265
InterPro IPR005225
IPR001806
IPR020849
PANTHER PTHR24070
Pfam PF00071
PRINTS PR00449
SMART SM00173
TIGRFAMs TIGR00231
PROSITE PS51421

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000139

Golgi membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0134

C

Seeded From UniProt

GO:0000165

MAPKKK cascade

Reactome:REACT_634

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0000166

nucleotide binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

Seeded From UniProt

GO:0000186

activation of MAPKK activity

Reactome:REACT_12005

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0000186

activation of MAPKK activity

Reactome:REACT_962

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0003924

GTPase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020849

F

Seeded From UniProt

GO:0003924

GTPase activity

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000029445

F

Seeded From UniProt

GO:0005525

GTP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001806

F

Seeded From UniProt

GO:0005525

GTP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005225

F

Seeded From UniProt

GO:0005525

GTP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020849

F

Seeded From UniProt

GO:0005525

GTP binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0342

F

Seeded From UniProt

GO:0005624

membrane fraction

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000029445

C

Seeded From UniProt

GO:0005794

Golgi apparatus

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0333

C

Seeded From UniProt

GO:0005886

plasma membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded From UniProt

GO:0005886

plasma membrane

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000036381

C

Seeded From UniProt

GO:0005886

plasma membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0039

C

Seeded From UniProt

GO:0005886

plasma membrane

Reactome:REACT_12001

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005886

plasma membrane

Reactome:REACT_12041

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005886

plasma membrane

Reactome:REACT_12386

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005886

plasma membrane

Reactome:REACT_12402

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005886

plasma membrane

Reactome:REACT_12516

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005886

plasma membrane

Reactome:REACT_16923

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005886

plasma membrane

Reactome:REACT_18366

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005886

plasma membrane

Reactome:REACT_2010

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005886

plasma membrane

Reactome:REACT_359

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005886

plasma membrane

Reactome:REACT_525

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005886

plasma membrane

Reactome:REACT_996

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0006184

GTP catabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020849

P

Seeded From UniProt

GO:0007165

signal transduction

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020849

P

Seeded From UniProt

GO:0007173

epidermal growth factor receptor signaling pathway

Reactome:REACT_9417

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0007264

small GTPase mediated signal transduction

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001806

P

Seeded From UniProt

GO:0007264

small GTPase mediated signal transduction

Reactome:REACT_12077

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0007265

Ras protein signal transduction

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000029445

P

Seeded From UniProt

GO:0007265

Ras protein signal transduction

Reactome:REACT_12033

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0007411

axon guidance

Reactome:REACT_18266

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0007596

blood coagulation

Reactome:REACT_604

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0008284

positive regulation of cell proliferation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000029445

P

Seeded From UniProt

GO:0008286

insulin receptor signaling pathway

Reactome:REACT_498

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0008321

Ral guanyl-nucleotide exchange factor activity

Reactome:REACT_12041

TAS: Traceable Author Statement

F

Seeded From UniProt

GO:0008542

visual learning

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000029445

P

Seeded From UniProt

GO:0016020

membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020849

C

Seeded From UniProt

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded From UniProt

GO:0030036

actin cytoskeleton organization

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000029445

P

Seeded From UniProt

GO:0032228

regulation of synaptic transmission, GABAergic

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000029445

P

Seeded From UniProt

GO:0035022

positive regulation of Rac protein signal transduction

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000029445

P

Seeded From UniProt

GO:0048011

nerve growth factor receptor signaling pathway

Reactome:REACT_11061

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0048169

regulation of long-term neuronal synaptic plasticity

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000029445

P

Seeded From UniProt

GO:0050900

leukocyte migration

Reactome:REACT_12051

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0051146

striated muscle cell differentiation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000029445

P

Seeded From UniProt

GO:0005794

Golgi apparatus

PMID:21968647[1]

IDA: Inferred from Direct Assay

C

Overexpression of PAQR10/PAQR11 also markedly increased Golgi localization of NRas and KRas4A (Figure2B and 2C), (summarized in Figure 2E).

complete

GO:0072600

establishment of protein localization in Golgi

PMID:21968647[1]

IMP: Inferred from Mutant Phenotype

P

Figure 2B

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Jin T et al. (2012) PAQR10 and PAQR11 mediate Ras signaling in the Golgi apparatus. Cell Res 22: 661-76 PubMed GONUTS page
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