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HUMAN:OBFC1
Contents |
| Species (Taxon ID) | Homo sapiens (Human). (taxon:9606) | |
| Gene Name(s) | OBFC1 | |
| Protein Name(s) |
| |
| External Links | ||
| UniProt Identifier | OBFC1_HUMAN | |
| UniProt Accessions | Q9H668, Q5TCZ0, | |
| EMBL | AK026212, AL133355, BC017400, | |
| RefSeq | NP_079204.2, | |
| IntAct | Q9H668, | |
| Ensembl | ENST00000224950, ENST00000369764, | |
| Pfam | PF09170, PF01336, | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000723 |
telomere maintenance |
IMP: Inferred from Mutant Phenotype |
P |
|||||
| GO:0000781 |
chromosome, telomeric region |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0000781 |
chromosome, telomeric region |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0276 |
C |
||||
| GO:0000784 |
nuclear chromosome, telomeric region |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000040944 |
C |
||||
| GO:0000784 |
nuclear chromosome, telomeric region |
IDA: Inferred from Direct Assay |
C |
|||||
| GO:0000784 |
nuclear chromosome, telomeric region |
IDA: Inferred from Direct Assay |
C |
|||||
| GO:0003676 |
nucleic acid binding |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0003677 |
DNA binding |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0003697 |
single-stranded DNA binding |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000040944 |
F |
||||
| GO:0003697 |
single-stranded DNA binding |
ISS: Inferred from Sequence or Structural Similarity |
F |
|||||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
|||||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
|||||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
|||||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000040944 |
C |
||||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0191 |
C |
||||
| GO:0005634 |
nucleus |
ISS: Inferred from Sequence or Structural Similarity |
C |
|||||
| GO:0005634 |
nucleus |
IDA: Inferred from Direct Assay |
C |
|||||
| GO:0005694 |
chromosome |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0010833 |
telomere maintenance via telomere lengthening |
IMP: Inferred from Mutant Phenotype |
P |
|||||
| GO:0043047 |
single-stranded telomeric DNA binding |
IDA: Inferred from Direct Assay |
F |
|||||
| GO:0045740 |
positive regulation of DNA replication |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000040944 |
P |
||||
| GO:0045740 |
positive regulation of DNA replication |
ISS: Inferred from Sequence or Structural Similarity |
P |
|||||
| GO:0070188 |
Stn1-Ten1 complex |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000040944 |
C |
| |||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Miyake Y et al. (2009) RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway. Mol Cell 36: 193-206 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Wan M et al. (2009) OB fold-containing protein 1 (OBFC1), a human homolog of yeast Stn1, associates with TPP1 and is implicated in telomere length regulation. J Biol Chem 284: 26725-31 PubMed GONUTS page
