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HUMAN:NSF

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Contents

Species (Taxon ID) Homo sapiens (Human). ([1])
Gene Name(s) NSF
Protein Name(s) Vesicle-fusing ATPase

N-ethylmaleimide-sensitive fusion protein NEM-sensitive fusion protein Vesicular-fusion protein NSF

External Links
EMBL U03985
AF135168
AF102846
AK290204
AC004098
AC138645
AC138688
AC217769
AC217778
AC217780
BC030613
IPI IPI00006451
PIR G01234
RefSeq NP_006169.2
UniGene Hs.431279
ProteinModelPortal P46459
SMR P46459
DIP DIP-389N
IntAct P46459
MINT MINT-1369243
STRING P46459
TCDB 1.F.1.1.1
PhosphoSite P46459
UCD-2DPAGE P46459
PRIDE P46459
Ensembl ENST00000398238
GeneID 4905
KEGG hsa:4905
UCSC uc002iku.2
CTD 4905
GeneCards GC17P040092
HGNC HGNC:8016
HPA CAB009324
CAB013645
HPA003154
MIM 601633
neXtProt NX_P46459
PharmGKB PA31793
eggNOG prNOG06329
HOGENOM HBG318848
HOVERGEN HBG000324
InParanoid P46459
OMA TMQAARC
OrthoDB EOG4DZ1TR
PhylomeDB P46459
Reactome REACT_13685
PMAP-CutDB P46459
ArrayExpress P46459
Bgee P46459
CleanEx HS_NSF
Genevestigator P46459
GermOnline ENSG00000073969
GO GO:0005829
GO:0005524
GO:0046872
GO:0015031
GO:0007268
InterPro IPR009010
IPR003593
IPR003959
IPR003960
IPR003338
IPR004201
Gene3D G3DSA:2.40.40.20
Pfam PF00004
PF02933
PF02359
SMART SM00382
SUPFAM SSF50692
PROSITE PS00674

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003593

F

Seeded From UniProt

GO:0000166

nucleotide binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

Seeded From UniProt

GO:0005488

binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR009010

F

Seeded From UniProt

GO:0005515

protein binding

PMID:16417406[1]

IPI: Inferred from Physical Interaction

UniProtKB:P55160

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003338

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003959

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003960

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004201

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

Seeded From UniProt

GO:0005737

cytoplasm

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded From UniProt

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

Seeded From UniProt

GO:0005737

cytoplasm

PMID:18029348[2]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0005795

Golgi stack

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000006361

C

Seeded From UniProt

GO:0005829

cytosol

Reactome:REACT_18320

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0006200

ATP catabolic process

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000006361

P

Seeded From UniProt

GO:0006810

transport

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0813

P

Seeded From UniProt

GO:0006813

potassium ion transport

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000099364

P

Seeded From UniProt

GO:0007268

synaptic transmission

Reactome:REACT_13477

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0007268

synaptic transmission

Reactome:REACT_13685

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0008022

protein C-terminus binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000006361

F

Seeded From UniProt

GO:0015031

protein transport

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0653

P

Seeded From UniProt

GO:0015031

protein transport

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000006361

P

Seeded From UniProt

GO:0016192

vesicle-mediated transport

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000006361

P

Seeded From UniProt

GO:0016787

hydrolase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0378

F

Seeded From UniProt

GO:0016887

ATPase activity

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000006361

F

Seeded From UniProt

GO:0017111

nucleoside-triphosphatase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003593

F

Seeded From UniProt

GO:0017137

Rab GTPase binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000006361

F

Seeded From UniProt

GO:0017157

regulation of exocytosis

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000006361

P

Seeded From UniProt

GO:0019905

syntaxin binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000099364

F

Seeded From UniProt

GO:0042623

ATPase activity, coupled

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000099364

F

Seeded From UniProt

GO:0043198

dendritic shaft

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000006361

C

Seeded From UniProt

GO:0046872

metal ion binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0479

F

Seeded From UniProt

GO:0006886

intracellular protein transport

PMID:22045810[3]

IMP: Inferred from Mutant Phenotype

P

Fig. 7BC

complete

GO:0045732

positive regulation of protein catabolic process

PMID:22045810[3]

IMP: Inferred from Mutant Phenotype

P

Fig. 7

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Weiner OD et al. (2006) Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxis. PLoS Biol 4: e38 PubMed GONUTS page
  2. Barbe L et al. (2008) Toward a confocal subcellular atlas of the human proteome. Mol Cell Proteomics 7: 499-508 PubMed GONUTS page
  3. 3.0 3.1 Sangwan V et al. (2011) Protein-tyrosine phosphatase 1B modulates early endosome fusion and trafficking of Met and epidermal growth factor receptors. J Biol Chem 286: 45000-13 PubMed GONUTS page
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