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HUMAN:NIN

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Contents

Species (Taxon ID) Homo sapiens (Human). (taxon:9606)
Gene Name(s) NIN ( synonyms: KIAA1565 )
Protein Name(s)
  • Ninein
  • hNinein
  • Glycogen synthase kinase 3 beta-interacting protein
  • GSK3B-interacting protein
External Links
UniProt Identifier NIN_HUMAN
UniProt Accessions Q8N4C6, A6NDB8, B7WPA3, C9JSB6, C9JSG2, C9JXL2, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61,
EMBL AF212162, AF302773, AF223937, AF223938, AF223939, AB046785, AL133485, AL606834, BC034708, BC065521, AY027794, AY027795, AY027796, AF186776, AK027054,
RefSeq NP_057434.4, NP_065972.3, NP_891989.2, NP_891991.1,
IntAct Q8N4C6,
Ensembl ENST00000382041,

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005813

centrosome

PMID:17139249[1]

IDA: Inferred from Direct Assay

C

Fig.8A

complete

GO:0005515

protein binding

PMID:17139249[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q96G01


F

Fig.8C

complete

GO:0000166

nucleotide binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

GO:0005509

calcium ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011992

F

GO:0005515

protein binding

PMID:12927815[2]

IPI: Inferred from Physical Interaction

UniProtKB:P49841

F

GO:0005515

protein binding

PMID:15147888[3]

IPI: Inferred from Physical Interaction

UniProtKB:P49841

F

GO:0005515

protein binding

PMID:15147888[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q9Y224

F

GO:0005515

protein binding

PMID:16154161[4]

IPI: Inferred from Physical Interaction

UniProtKB:O75925

F

GO:0005515

protein binding

PMID:16154161[4]

IPI: Inferred from Physical Interaction

UniProtKB:O75928

F

GO:0005515

protein binding

PMID:16154161[4]

IPI: Inferred from Physical Interaction

UniProtKB:P63165

F

GO:0005515

protein binding

PMID:16154161[4]

IPI: Inferred from Physical Interaction

UniProtKB:P63279

F

GO:0005525

GTP binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0342

F

GO:0005737

cytoplasm

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

GO:0005813

centrosome

PMID:12927815[2]

IDA: Inferred from Direct Assay

C

GO:0005813

centrosome

PMID:21399614[5]

IDA: Inferred from Direct Assay

C

GO:0005815

microtubule organizing center

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0048

C

GO:0005856

cytoskeleton

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0206

C

GO:0005874

microtubule

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0493

C

GO:0051642

centrosome localization

PMID:16154161[4]

TAS: Traceable Author Statement

P


Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Fumoto K et al. (2006) GSK-3beta-regulated interaction of BICD with dynein is involved in microtubule anchorage at centrosome. EMBO J 25: 5670-82 PubMed GONUTS page
  2. 2.0 2.1 Chen CH et al. (2003) Molecular characterization of human ninein protein: two distinct subdomains required for centrosomal targeting and regulating signals in cell cycle. Biochem Biophys Res Commun 308: 975-83 PubMed GONUTS page
  3. 3.0 3.1 Howng SL et al. (2004) A novel ninein-interaction protein, CGI-99, blocks ninein phosphorylation by GSK3beta and is highly expressed in brain tumors. FEBS Lett 566: 162-8 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 Cheng TS et al. (2006) SUMO-1 modification of centrosomal protein hNinein promotes hNinein nuclear localization. Life Sci 78: 1114-20 PubMed GONUTS page
  5. Jakobsen L et al. (2011) Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. EMBO J 30: 1520-35 PubMed GONUTS page
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