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HUMAN:NGLY1
Contents |
| Species (Taxon ID) | Homo sapiens (Human). (taxon:9606) | |
| Gene Name(s) | NGLY1 ( synonyms: PNG1 ) | |
| Protein Name(s) |
| |
| External Links | ||
| UniProt Identifier | NGLY1_HUMAN | |
| UniProt Accessions | Q96IV0, Q59FB1, Q6PJD8, Q9BVR8, Q9NR70, | |
| EMBL | AF250924, AB209549, BC000963, BC007226, BC017220, | |
| RefSeq | NP_001138765.1, NP_001138767.1, NP_060767.2, | |
| PDB | 2CCQ, 2CM0, | |
| Ensembl | ENST00000280700, | |
| Pfam | PF04721, PF09409, PF01841, | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005737 |
cytoplasm |
IDA: Inferred from Direct Assay |
C |
Source: UniProtKB |
||||
| GO:0046872 |
metal ion binding |
IEA: Inferred from Electronic Annotation |
F |
Source: UniProtKB-KW |
||||
| GO:0000224 |
peptide-N4-(N-acetyl-beta-glucosaminyl)aspa... |
IEA: Inferred from Electronic Annotation |
F |
Source: EC |
||||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Source: UniProtKB |
||||
|
incorrect (CACAO) |
GO:0006516 |
glycoprotein catabolic process |
IMP: Inferred from Mutant Phenotype |
P |
FIg 2.B. Does not play a role in glycoprotein catabolic process. Failure to detect activity in the soluble fractions prepared for the larval homogenate. Source: UniProtKB |
complete | ||
| GO:0000224 |
peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
|||||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000022310 |
C |
||||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0086 |
C |
||||
| GO:0005737 |
cytoplasm |
IDA: Inferred from Direct Assay |
C |
|||||
| GO:0006516 |
glycoprotein catabolic process |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0006516 |
glycoprotein catabolic process |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000022310 |
P |
||||
| GO:0006516 |
glycoprotein catabolic process |
IDA: Inferred from Direct Assay |
P |
|||||
| GO:0016787 |
hydrolase activity |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0046872 |
metal ion binding |
IEA: Inferred from Electronic Annotation |
F |
| ||||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Funakoshi Y et al. (2010) Evidence for an essential deglycosylation-independent activity of PNGase in Drosophila melanogaster. PLoS One 5: e10545 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Katiyar S et al. (2004) A complex between peptide:N-glycanase and two proteasome-linked proteins suggests a mechanism for the degradation of misfolded glycoproteins. Proc Natl Acad Sci U S A 101: 13774-9 PubMed GONUTS page
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