Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

HUMAN:NGF

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Homo sapiens (Human). ([1])
Gene Name(s) NGF (synonyms: NGFB)
Protein Name(s) Beta-nerve growth factor

Beta-NGF

External Links
EMBL V01511
M21062
AF150960
AB037517
AF411526
CR541855
BT019733
AL049825
CH471122
BC032517
BC126148
BC126150
X52599
IPI IPI00000076
PIR A01399
RefSeq NP_002497.2
UniGene Hs.2561
PDB 1SG1
1WWW
2IFG
PDBsum 1SG1
1WWW
2IFG
ProteinModelPortal P01138
SMR P01138
DIP DIP-5712N
MINT MINT-122414
STRING P01138
PRIDE P01138
Ensembl ENST00000369512
GeneID 4803
KEGG hsa:4803
UCSC uc001efu.1
CTD 4803
GeneCards GC01M113686
H-InvDB HIX0028607
HGNC HGNC:7808
MIM 162030
608654
neXtProt NX_P01138
Orphanet 64752
PharmGKB PA162397475
HOGENOM HBG713304
HOVERGEN HBG006494
InParanoid P01138
OMA CVLSRKA
OrthoDB EOG4BRWMZ
PhylomeDB P01138
Pathway_Interaction_DB trkrpathway
p75ntrpathway
pi3kplctrkpathway
Reactome REACT_11061
DrugBank DB01407
NextBio 18514
PMAP-CutDB P01138
ArrayExpress P01138
Bgee P01138
CleanEx HS_NGF
Genevestigator P01138
GermOnline ENSG00000134259
GO GO:0005768
GO:0005796
GO:0008083
GO:0005163
GO:0000186
GO:0007202
GO:0006916
GO:0006915
GO:0008624
GO:0045786
GO:0032455
GO:0048011
GO:0048015
GO:0007265
InterPro IPR020408
IPR002072
IPR020425
IPR020437
IPR019846
PANTHER PTHR11589
Pfam PF00243
PIRSF PIRSF001789
PRINTS PR01925
PR00268
PR01913
ProDom PD002052
SMART SM00140
PROSITE PS00248
PS50270

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000186

activation of MAPKK activity

Reactome:REACT_12005

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0004871

signal transducer activity

PMID:6688123[1]

TAS: Traceable Author Statement

F

Seeded From UniProt

GO:0005057

receptor signaling protein activity

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000102538

F

Seeded From UniProt

GO:0005102

receptor binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002072

F

Seeded From UniProt

GO:0005163

nerve growth factor receptor binding

PMID:14985763[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q99523

F

Seeded From UniProt

GO:0005576

extracellular region

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0964

C

Seeded From UniProt

GO:0005576

extracellular region

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000102538

C

Seeded From UniProt

GO:0005576

extracellular region

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000022200

C

Seeded From UniProt

GO:0005576

extracellular region

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0243

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_10014

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_10024

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_10033

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_10088

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_11995

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_11998

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_12000

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_12003

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_12017

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_12036

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_12037

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_12057

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_12059

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_12061

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_12066

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_12071

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_12384

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_12385

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_13404

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_13439

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_13502

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_13512

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_13533

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_13536

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_13555

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_13584

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_13586

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_13649

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_13657

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_13684

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_13710

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_13726

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_13753

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_13754

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_13785

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005615

extracellular space

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000022200

C

Seeded From UniProt

GO:0005768

endosome

Reactome:REACT_10033

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005768

endosome

Reactome:REACT_12010

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005768

endosome

Reactome:REACT_12015

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005768

endosome

Reactome:REACT_12023

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005768

endosome

Reactome:REACT_12059

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005768

endosome

Reactome:REACT_12063

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005788

endoplasmic reticulum lumen

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000102538

C

Seeded From UniProt

GO:0005788

endoplasmic reticulum lumen

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000022200

C

Seeded From UniProt

GO:0005796

Golgi lumen

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000022200

C

Seeded From UniProt

GO:0005796

Golgi lumen

Reactome:REACT_10024

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005796

Golgi lumen

Reactome:REACT_10058

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0006915

apoptosis

Reactome:REACT_13526

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0006915

apoptosis

Reactome:REACT_13638

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0006915

apoptosis

Reactome:REACT_13643

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0006916

anti-apoptosis

Reactome:REACT_13537

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0006954

inflammatory response

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000022200

P

Seeded From UniProt

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

Reactome:REACT_11064

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0007202

activation of phospholipase C activity

Reactome:REACT_12079

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0007264

small GTPase mediated signal transduction

Reactome:REACT_12077

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0007265

Ras protein signal transduction

Reactome:REACT_12033

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0007422

peripheral nervous system development

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000102538

P

Seeded From UniProt

GO:0007613

memory

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000022200

P

Seeded From UniProt

GO:0008083

growth factor activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0339

F

Seeded From UniProt

GO:0008284

positive regulation of cell proliferation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000022200

P

Seeded From UniProt

GO:0008344

adult locomotory behavior

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000022200

P

Seeded From UniProt

GO:0008624

induction of apoptosis by extracellular signals

Reactome:REACT_13720

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0008624

induction of apoptosis by extracellular signals

Reactome:REACT_13806

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0009314

response to radiation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000022200

P

Seeded From UniProt

GO:0009612

response to mechanical stimulus

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000022200

P

Seeded From UniProt

GO:0010033

response to organic substance

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000022200

P

Seeded From UniProt

GO:0014070

response to organic cyclic compound

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000022200

P

Seeded From UniProt

GO:0019233

sensory perception of pain

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000102538

P

Seeded From UniProt

GO:0030307

positive regulation of cell growth

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000022200

P

Seeded From UniProt

GO:0031175

neuron projection development

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000022200

P

Seeded From UniProt

GO:0031954

positive regulation of protein autophosphorylation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000022200

P

Seeded From UniProt

GO:0032455

nerve growth factor processing

Reactome:REACT_11062

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0032496

response to lipopolysaccharide

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000022200

P

Seeded From UniProt

GO:0035094

response to nicotine

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000022200

P

Seeded From UniProt

GO:0042493

response to drug

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000022200

P

Seeded From UniProt

GO:0043434

response to peptide hormone stimulus

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000022200

P

Seeded From UniProt

GO:0043524

negative regulation of neuron apoptosis

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000102538

P

Seeded From UniProt

GO:0045664

regulation of neuron differentiation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000102538

P

Seeded From UniProt

GO:0045773

positive regulation of axon extension

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000102538

P

Seeded From UniProt

GO:0045786

negative regulation of cell cycle

Reactome:REACT_13695

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0046928

regulation of neurotransmitter secretion

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000102538

P

Seeded From UniProt

GO:0048011

nerve growth factor receptor signaling pathway

Reactome:REACT_11060

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0048011

nerve growth factor receptor signaling pathway

Reactome:REACT_11061

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0048011

nerve growth factor receptor signaling pathway

Reactome:REACT_13724

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0048011

nerve growth factor receptor signaling pathway

Reactome:REACT_13776

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0048015

phosphatidylinositol-mediated signaling

Reactome:REACT_12464

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0050770

regulation of axonogenesis

Reactome:REACT_13620

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0050772

positive regulation of axonogenesis

Reactome:REACT_13779

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0051091

positive regulation of sequence-specific DNA binding transcription factor activity

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000022200

P

Seeded From UniProt

GO:0051384

response to glucocorticoid stimulus

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000022200

P

Seeded From UniProt

GO:0051388

positive regulation of nerve growth factor receptor signaling pathway

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000022200

P

Seeded From UniProt

GO:0051602

response to electrical stimulus

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000022200

P

Seeded From UniProt

GO:0014056

regulation of acetylcholine secretion

PMID:21702000[3]

IDA: Inferred from Direct Assay

P

Fig 1

complete

GO:0050908

detection of light stimulus involved in visual perception

PMID:21702000[3]

IDA: Inferred from Direct Assay

P

Fig 2

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ Ullrich A et al. (1983) Human beta-nerve growth factor gene sequence highly homologous to that of mouse. Nature 303: 821-5 PubMed GONUTS page
  2. ↑ Nykjaer A et al. (2004) Sortilin is essential for proNGF-induced neuronal cell death. Nature 427: 843-8 PubMed GONUTS page
  3. ↑ 3.0 3.1 Chiaretti A et al. (2011) Neuroprotective role of nerve growth factor in hypoxicischemic injury. From brain to skin. Arch Ital Biol 149: 275-82 PubMed GONUTS page
Retrieved from "http://gowiki.tamu.edu/wiki/index.php/HUMAN:NGF"
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox