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HUMAN:NEK3

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Contents

Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) NEK3
Protein Name(s) Serine/threonine-protein kinase Nek3

HSPK 36 Never in mitosis A-related kinase 3 NimA-related protein kinase 3

External Links
UniProt P51956
EMBL AB072828
AK290259
AL139082
CH471075
BC019916
Z29067
Z25434
IPI IPI00943072
IPI01020856
PIR I38224
RefSeq NP_001139571.1
NP_002489.1
NP_689933.1
UniGene Hs.409989
ProteinModelPortal P51956
SMR P51956
IntAct P51956
STRING P51956
PhosphoSite P51956
DMDM 20178297
PRIDE P51956
Ensembl ENST00000339406
ENST00000378101
GeneID 4752
KEGG hsa:4752
CTD 4752
GeneCards GC13M052706
H-InvDB HIX0011338
HGNC HGNC:7746
MIM 604044
neXtProt NX_P51956
PharmGKB PA31547
eggNOG prNOG09199
HOVERGEN HBG003063
PhylomeDB P51956
BRENDA 2.7.11.1
NextBio 18314
ArrayExpress P51956
Bgee P51956
CleanEx HS_NEK3
Genevestigator P51956
GermOnline ENSG00000136098
GO GO:0030424
GO:0005737
GO:0005634
GO:0005524
GO:0046872
GO:0005515
GO:0004674
GO:0051301
GO:0007067
InterPro IPR011009
IPR000719
IPR017441
IPR017442
IPR008271
IPR002290
KO K08857
Pfam PF00069
SMART SM00220
SUPFAM SSF56112
PROSITE PS00107
PS50011
PS00108

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

Seeded From UniProt

GO:0004672

protein kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

F

Seeded From UniProt

GO:0004672

protein kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002290

F

Seeded From UniProt

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008271

F

Seeded From UniProt

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0723

F

Seeded From UniProt

GO:0004674

protein serine/threonine kinase activity

PMID:7522034[1]

NAS: Non-traceable Author Statement

F

Seeded From UniProt

GO:0005515

protein binding

PMID:15618286[2]

IPI: Inferred from Physical Interaction

UniProtKB:P52735

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002290

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017441

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000029

NAS: Non-traceable Author Statement

F

Seeded From UniProt

GO:0005634

nucleus

PMID:7522034[1]

NAS: Non-traceable Author Statement

C

Seeded From UniProt

GO:0005737

cytoplasm

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded From UniProt

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

Seeded From UniProt

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

P

Seeded From UniProt

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002290

P

Seeded From UniProt

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008271

P

Seeded From UniProt

GO:0006468

protein phosphorylation

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q9R0A5

P

Seeded From UniProt

GO:0006468

protein phosphorylation

GO_REF:0000029

NAS: Non-traceable Author Statement

P

Seeded From UniProt

GO:0007049

cell cycle

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0131

P

Seeded From UniProt

GO:0007049

cell cycle

GO_REF:0000029

NAS: Non-traceable Author Statement

P

Seeded From UniProt

GO:0007067

mitosis

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0498

P

Seeded From UniProt

GO:0007067

mitosis

PMID:7522034[1]

NAS: Non-traceable Author Statement

P

Seeded From UniProt

GO:0016301

kinase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

F

Seeded From UniProt

GO:0016310

phosphorylation

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

P

Seeded From UniProt

GO:0016740

transferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded From UniProt

GO:0016772

transferase activity, transferring phosphorus-containing groups

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

Seeded From UniProt

GO:0030424

axon

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0279

C

Seeded From UniProt

GO:0042995

cell projection

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0966

C

Seeded From UniProt

GO:0046872

metal ion binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0479

F

Seeded From UniProt

GO:0051301

cell division

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0132

P

Seeded From UniProt


Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Schultz SJ et al. (1994) Cell cycle-dependent expression of Nek2, a novel human protein kinase related to the NIMA mitotic regulator of Aspergillus nidulans. Cell Growth Differ 5: 625-35 PubMed GONUTS page
  2. Miller SL et al. (2005) Novel association of Vav2 and Nek3 modulates signaling through the human prolactin receptor. Mol Endocrinol 19: 939-49 PubMed GONUTS page
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