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HUMAN:MCHR1

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Contents

Species (Taxon ID) Homo sapiens (Human). ([1])
Gene Name(s) MCHR1 (synonyms: GPR24, SLC1)
Protein Name(s) Melanin-concentrating hormone receptor 1

MCH receptor 1 MCH-R1 MCHR-1 G-protein coupled receptor 24 MCH-1R MCH1R MCHR SLC-1 Somatostatin receptor-like protein

External Links
EMBL AB063174
AF490537
CR456497
BT006725
AY562945
AK314857
Z86090
CH471095
BC001736
BC021146
U71092
IPI IPI00017705
PIR JC7080
RefSeq NP_005288.3
UniGene Hs.248122
ProteinModelPortal Q99705
SMR Q99705
STRING Q99705
PhosphoSite Q99705
PRIDE Q99705
Ensembl ENST00000249016
GeneID 2847
KEGG hsa:2847
UCSC uc003ayz.1
CTD 2847
GeneCards GC22P024040
H-InvDB HIX0016506
HGNC HGNC:4479
HPA HPA004149
MIM 601751
neXtProt NX_Q99705
PharmGKB PA28867
GeneTree ENSGT00600000084032
HOGENOM HBG715643
HOVERGEN HBG105726
InParanoid Q99705
OMA LYWFTLY
OrthoDB EOG43XV3F
PhylomeDB Q99705
Reactome REACT_14797
NextBio 11231
ArrayExpress Q99705
Bgee Q99705
CleanEx HS_MCHR1
Genevestigator Q99705
GermOnline ENSG00000128285
GO GO:0005887
GO:0031513
GO:0008188
GO:0007204
GO:0007631
GO:0006091
GO:0007193
InterPro IPR000276
IPR017452
IPR004047
IPR008361
Pfam PF00001
PRINTS PR00237
PR01507
PR01783
PROSITE PS00237
PS50262

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004871

signal transducer activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0807

F

Seeded From UniProt

GO:0004872

receptor activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0675

F

Seeded From UniProt

GO:0004930

G-protein coupled receptor activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0297

F

Seeded From UniProt

GO:0004930

G-protein coupled receptor activity

PMID:10421367[1]

TAS: Traceable Author Statement

F

Seeded From UniProt

GO:0005886

plasma membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded From UniProt

GO:0005886

plasma membrane

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000062329

C

Seeded From UniProt

GO:0005886

plasma membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0039

C

Seeded From UniProt

GO:0005886

plasma membrane

Reactome:REACT_15291

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005886

plasma membrane

Reactome:REACT_15538

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005886

plasma membrane

Reactome:REACT_22239

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005886

plasma membrane

Reactome:REACT_22263

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005886

plasma membrane

Reactome:REACT_22289

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005886

plasma membrane

Reactome:REACT_22436

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005886

plasma membrane

Reactome:REACT_25247

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005887

integral to plasma membrane

PMID:10421367[1]

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0006091

generation of precursor metabolites and energy

PMID:10421367[1]

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0007165

signal transduction

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0807

P

Seeded From UniProt

GO:0007166

cell surface receptor linked signaling pathway

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000025564

P

Seeded From UniProt

GO:0007186

G-protein coupled receptor protein signaling pathway

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000276

P

Seeded From UniProt

GO:0007186

G-protein coupled receptor protein signaling pathway

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008361

P

Seeded From UniProt

GO:0007186

G-protein coupled receptor protein signaling pathway

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0297

P

Seeded From UniProt

GO:0007186

G-protein coupled receptor protein signaling pathway

PMID:10421368[2]

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0007193

inhibition of adenylate cyclase activity by G-protein signaling pathway

PMID:10421367[1]

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0007204

elevation of cytosolic calcium ion concentration

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000025564

P

Seeded From UniProt

GO:0007204

elevation of cytosolic calcium ion concentration

PMID:10421367[1]

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0007218

neuropeptide signaling pathway

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004047

P

Seeded From UniProt

GO:0007218

neuropeptide signaling pathway

PMID:10860944[3]

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0007631

feeding behavior

PMID:10421367[1]

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0008022

protein C-terminus binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000025564

F

Seeded From UniProt

GO:0008188

neuropeptide receptor activity

PMID:10860944[3]

TAS: Traceable Author Statement

F

Seeded From UniProt

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded From UniProt

GO:0016021

integral to membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000276

C

Seeded From UniProt

GO:0016021

integral to membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004047

C

Seeded From UniProt

GO:0016021

integral to membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008361

C

Seeded From UniProt

GO:0016021

integral to membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded From UniProt

GO:0030273

melanin-concentrating hormone receptor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004047

F

Seeded From UniProt

GO:0030273

melanin-concentrating hormone receptor activity

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000025564

F

Seeded From UniProt

GO:0031513

nonmotile primary cilium

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000062329

C

Seeded From UniProt

GO:0031513

nonmotile primary cilium

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q8JZL2

C

Seeded From UniProt

GO:0042562

hormone binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000025564

F

Seeded From UniProt

GO:0051928

positive regulation of calcium ion transport

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000025564

P

Seeded From UniProt


Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Chambers J et al. (1999) Melanin-concentrating hormone is the cognate ligand for the orphan G-protein-coupled receptor SLC-1. Nature 400: 261-5 PubMed GONUTS page
  2. Saito Y et al. (1999) Molecular characterization of the melanin-concentrating-hormone receptor. Nature 400: 265-9 PubMed GONUTS page
  3. 3.0 3.1 Macdonald D et al. (2000) Molecular characterization of the melanin-concentrating hormone/receptor complex: identification of critical residues involved in binding and activation. Mol Pharmacol 58: 217-25 PubMed GONUTS page
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