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HUMAN:MCHR1
Contents |
| Species (Taxon ID) | Homo sapiens (Human). ([1]) | |
| Gene Name(s) | MCHR1 (synonyms: GPR24, SLC1) | |
| Protein Name(s) | Melanin-concentrating hormone receptor 1
MCH receptor 1 MCH-R1 MCHR-1 G-protein coupled receptor 24 MCH-1R MCH1R MCHR SLC-1 Somatostatin receptor-like protein | |
| External Links | ||
| EMBL | AB063174 AF490537 CR456497 BT006725 AY562945 AK314857 Z86090 CH471095 BC001736 BC021146 U71092 | |
| IPI | IPI00017705 | |
| PIR | JC7080 | |
| RefSeq | NP_005288.3 | |
| UniGene | Hs.248122 | |
| ProteinModelPortal | Q99705 | |
| SMR | Q99705 | |
| STRING | Q99705 | |
| PhosphoSite | Q99705 | |
| PRIDE | Q99705 | |
| Ensembl | ENST00000249016 | |
| GeneID | 2847 | |
| KEGG | hsa:2847 | |
| UCSC | uc003ayz.1 | |
| CTD | 2847 | |
| GeneCards | GC22P024040 | |
| H-InvDB | HIX0016506 | |
| HGNC | HGNC:4479 | |
| HPA | HPA004149 | |
| MIM | 601751 | |
| neXtProt | NX_Q99705 | |
| PharmGKB | PA28867 | |
| GeneTree | ENSGT00600000084032 | |
| HOGENOM | HBG715643 | |
| HOVERGEN | HBG105726 | |
| InParanoid | Q99705 | |
| OMA | LYWFTLY | |
| OrthoDB | EOG43XV3F | |
| PhylomeDB | Q99705 | |
| Reactome | REACT_14797 | |
| NextBio | 11231 | |
| ArrayExpress | Q99705 | |
| Bgee | Q99705 | |
| CleanEx | HS_MCHR1 | |
| Genevestigator | Q99705 | |
| GermOnline | ENSG00000128285 | |
| GO | GO:0005887 GO:0031513 GO:0008188 GO:0007204 GO:0007631 GO:0006091 GO:0007193 | |
| InterPro | IPR000276 IPR017452 IPR004047 IPR008361 | |
| Pfam | PF00001 | |
| PRINTS | PR00237 PR01507 PR01783 | |
| PROSITE | PS00237 PS50262 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004871 |
signal transducer activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004872 |
receptor activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004930 |
G-protein coupled receptor activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004930 |
G-protein coupled receptor activity |
TAS: Traceable Author Statement |
|
F |
Seeded From UniProt |
|||
| GO:0005886 |
plasma membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005886 |
plasma membrane |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000062329 |
C |
Seeded From UniProt |
|||
| GO:0005886 |
plasma membrane |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0039 |
C |
Seeded From UniProt |
|||
| GO:0005886 |
plasma membrane |
Reactome:REACT_15291 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0005886 |
plasma membrane |
Reactome:REACT_15538 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0005886 |
plasma membrane |
Reactome:REACT_22239 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0005886 |
plasma membrane |
Reactome:REACT_22263 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0005886 |
plasma membrane |
Reactome:REACT_22289 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0005886 |
plasma membrane |
Reactome:REACT_22436 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0005886 |
plasma membrane |
Reactome:REACT_25247 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0005887 |
integral to plasma membrane |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
|||
| GO:0006091 |
generation of precursor metabolites and energy |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0007165 |
signal transduction |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007166 |
cell surface receptor linked signaling pathway |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025564 |
P |
Seeded From UniProt |
|||
| GO:0007186 |
G-protein coupled receptor protein signaling pathway |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007186 |
G-protein coupled receptor protein signaling pathway |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007186 |
G-protein coupled receptor protein signaling pathway |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007186 |
G-protein coupled receptor protein signaling pathway |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0007193 |
inhibition of adenylate cyclase activity by G-protein signaling pathway |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0007204 |
elevation of cytosolic calcium ion concentration |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025564 |
P |
Seeded From UniProt |
|||
| GO:0007204 |
elevation of cytosolic calcium ion concentration |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0007218 |
neuropeptide signaling pathway |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007218 |
neuropeptide signaling pathway |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0007631 |
feeding behavior |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0008022 |
protein C-terminus binding |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025564 |
F |
Seeded From UniProt |
|||
| GO:0008188 |
neuropeptide receptor activity |
TAS: Traceable Author Statement |
|
F |
Seeded From UniProt |
|||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0030273 |
melanin-concentrating hormone receptor activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0030273 |
melanin-concentrating hormone receptor activity |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025564 |
F |
Seeded From UniProt |
|||
| GO:0031513 |
nonmotile primary cilium |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000062329 |
C |
Seeded From UniProt |
|||
| GO:0031513 |
nonmotile primary cilium |
ISS: Inferred from Sequence or Structural Similarity |
C |
Seeded From UniProt |
||||
| GO:0042562 |
hormone binding |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025564 |
F |
Seeded From UniProt |
|||
| GO:0051928 |
positive regulation of calcium ion transport |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000025564 |
P |
Seeded From UniProt |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Chambers J et al. (1999) Melanin-concentrating hormone is the cognate ligand for the orphan G-protein-coupled receptor SLC-1. Nature 400: 261-5 PubMed GONUTS page
- ↑ Saito Y et al. (1999) Molecular characterization of the melanin-concentrating-hormone receptor. Nature 400: 265-9 PubMed GONUTS page
- ↑ 3.0 3.1 Macdonald D et al. (2000) Molecular characterization of the melanin-concentrating hormone/receptor complex: identification of critical residues involved in binding and activation. Mol Pharmacol 58: 217-25 PubMed GONUTS page