HUMAN:MA2B1

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Species (Taxon ID)	Homo sapiens (Human). (taxon:9606)
Gene Name(s)	MAN2B1 ( synonyms: LAMAN, MANB )
Protein Name(s)	Lysosomal alpha-mannosidase Laman Lysosomal acid alpha-mannosidase Mannosidase alpha class 2B member 1 Mannosidase alpha-B Lysosomal alpha-mannosidase A peptide Lysosomal alpha-mannosidase B peptide Lysosomal alpha-mannosidase C peptide Lysosomal alpha-mannosidase D peptide Lysosomal alpha-mannosidase E peptide
External Links
UniProt Identifier	MA2B1_HUMAN
UniProt Accessions	O00754, O15330, Q16680, Q93094, Q9BW13,
EMBL	U05572, U60266, U60899, U60885, U60886, U60887, U60888, U60889, U60890, U60891, U60892, U60893, U60894, U60895, U60896, U60897, U60898, BC000736, U68567,
RefSeq	NP_000519.2, NP_001166969.1,
Ensembl	ENST00000456935,
Pfam	PF09261, PF01074, PF07748,

Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect
	GO:0003824	catalytic activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011013	F
	GO:0003824	catalytic activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011330	F
	GO:0003824	catalytic activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013780	F
	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR015341	F
	GO:0004559	alpha-mannosidase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000602	F
	GO:0004559	alpha-mannosidase activity	GO_REF:0000003	IEA: Inferred from Electronic Annotation	EC:3.2.1.24	F
	GO:0004559	alpha-mannosidase activity	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000034121	F
	GO:0004559	alpha-mannosidase activity	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000030766	F
	GO:0004559	alpha-mannosidase activity	PMID:8910458^[1]	TAS: Traceable Author Statement		F
	GO:0005537	mannose binding	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000030766	F
	GO:0005625	soluble fraction	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000030766	C
	GO:0005764	lysosome		IEA: Inferred from Electronic Annotation	SP_KW:KW-0458	C
	GO:0005764	lysosome	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000030766	C
	GO:0005764	lysosome	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0158	C
	GO:0005975	carbohydrate metabolic process	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000602	P
	GO:0005975	carbohydrate metabolic process	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011013	P
	GO:0005975	carbohydrate metabolic process	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011330	P
	GO:0005975	carbohydrate metabolic process	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013780	P
	GO:0006013	mannose metabolic process	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011682	P
	GO:0006013	mannose metabolic process	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000034121	P
	GO:0006464	protein modification process	PMID:8910458^[1]	IDA: Inferred from Direct Assay		P
	GO:0006517	protein deglycosylation	PMID:8910458^[1]	TAS: Traceable Author Statement		P
	GO:0007611	learning or memory	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000034121	P
	GO:0008152	metabolic process		IEA: Inferred from Electronic Annotation	SP_KW:KW-0326	P
	GO:0008270	zinc ion binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR015341	F
	GO:0015923	mannosidase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011682	F
	GO:0016787	hydrolase activity		IEA: Inferred from Electronic Annotation	SP_KW:KW-0378	F
	GO:0016798	hydrolase activity, acting on glycosyl bonds		IEA: Inferred from Electronic Annotation	SP_KW:KW-0326	F
	GO:0030246	carbohydrate binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011013	F
	GO:0043169	cation binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013780	F
	GO:0046872	metal ion binding		IEA: Inferred from Electronic Annotation	SP_KW:KW-0479	F
	GO:0003824	catalytic activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011013	F
	GO:0003824	catalytic activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011330	F
	GO:0003824	catalytic activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013780	F
	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR015341	F
	GO:0004559	alpha-mannosidase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000602	F
	GO:0004559	alpha-mannosidase activity	GO_REF:0000003	IEA: Inferred from Electronic Annotation	EC:3.2.1.24	F
	GO:0004559	alpha-mannosidase activity	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000030766	F
	GO:0004559	alpha-mannosidase activity	PMID:8910458^[1]	TAS: Traceable Author Statement		F
	GO:0005537	mannose binding	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000030766	F
	GO:0005625	soluble fraction	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000030766	C
	GO:0005764	lysosome	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0458	C
	GO:0005764	lysosome	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000030766	C
	GO:0005764	lysosome	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0158	C
	GO:0005975	carbohydrate metabolic process	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000602	P
	GO:0005975	carbohydrate metabolic process	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011013	P
	GO:0005975	carbohydrate metabolic process	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011330	P
	GO:0005975	carbohydrate metabolic process	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013780	P
	GO:0006013	mannose metabolic process	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011682	P
	GO:0006464	protein modification process	PMID:8910458^[1]	IDA: Inferred from Direct Assay		P
	GO:0006517	protein deglycosylation	PMID:8910458^[1]	TAS: Traceable Author Statement		P
	GO:0008152	metabolic process	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0326	P
	GO:0008270	zinc ion binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR015341	F
	GO:0015923	mannosidase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011682	F
	GO:0016787	hydrolase activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0378	F
	GO:0016798	hydrolase activity, acting on glycosyl bonds	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0326	F
	GO:0030246	carbohydrate binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011013	F
	GO:0043169	cation binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013780	F
	GO:0046872	metal ion binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0479	F
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 Liao YF et al. (1996) Cloning, expression, purification, and characterization of the human broad specificity lysosomal acid alpha-mannosidase. J Biol Chem 271: 28348-58 PubMed GONUTS page

[PMID:8910458-0] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 Liao YF et al. (1996) Cloning, expression, purification, and characterization of the human broad specificity lysosomal acid alpha-mannosidase. J Biol Chem 271: 28348-58 PubMed GONUTS page

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HUMAN:MA2B1

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