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HUMAN:HEM6
Contents |
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | CPOX (synonyms: CPO, CPX) | |
| Protein Name(s) | Coproporphyrinogen-III oxidase, mitochondrial
COX Coprogen oxidase Coproporphyrinogenase | |
| External Links | ||
| UniProt | P36551 | |
| EMBL | Z34531 Z34803 Z34804 Z34805 Z34806 Z34807 Z34808 AK290140 AK223481 CH471052 BC017210 BC023551 BC023554 D16611 Z28409 | |
| IPI | IPI00093057 | |
| PIR | I52444 | |
| RefSeq | NP_000088.3 | |
| UniGene | Hs.476982 | |
| PDB | 2AEX | |
| PDBsum | 2AEX | |
| ProteinModelPortal | P36551 | |
| SMR | P36551 | |
| IntAct | P36551 | |
| STRING | P36551 | |
| PhosphoSite | P36551 | |
| DMDM | 67476671 | |
| PeptideAtlas | P36551 | |
| PRIDE | P36551 | |
| Ensembl | ENST00000264193 | |
| GeneID | 1371 | |
| KEGG | hsa:1371 | |
| NMPDR | fig|9606.3.peg.22874 | |
| UCSC | uc003dsx.1 | |
| CTD | 1371 | |
| GeneCards | GC03M098239 | |
| H-InvDB | HIX0003491 | |
| HGNC | HGNC:2321 | |
| HPA | HPA015736 | |
| MIM | 121300 612732 | |
| neXtProt | NX_P36551 | |
| Orphanet | 79273 | |
| PharmGKB | PA134979958 | |
| eggNOG | prNOG10857 | |
| GeneTree | ENSGT00390000017311 | |
| HOGENOM | HBG631180 | |
| HOVERGEN | HBG051897 | |
| InParanoid | P36551 | |
| OMA | VFKPWCD | |
| PhylomeDB | P36551 | |
| BRENDA | 1.3.3.3 | |
| Reactome | REACT_111217 | |
| NextBio | 5561 | |
| ArrayExpress | P36551 | |
| Bgee | P36551 | |
| CleanEx | HS_CPO HS_CPOX | |
| Genevestigator | P36551 | |
| GermOnline | ENSG00000080819 | |
| GO | GO:0005758 GO:0004109 GO:0042803 | |
| InterPro | IPR001260 IPR018375 | |
| Gene3D | G3DSA:3.40.1500.10 | |
| KO | K00228 | |
| PANTHER | PTHR10755 | |
| Pfam | PF01218 | |
| PRINTS | PR00073 | |
| SUPFAM | SSF102886 | |
| PROSITE | PS01021 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004109 |
coproporphyrinogen oxidase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004109 |
coproporphyrinogen oxidase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004109 |
coproporphyrinogen oxidase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004109 |
coproporphyrinogen oxidase activity |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000055455 |
F |
Seeded From UniProt |
|||
| GO:0004109 |
coproporphyrinogen oxidase activity |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000002257 |
F |
Seeded From UniProt |
|||
| GO:0004109 |
coproporphyrinogen oxidase activity |
TAS: Traceable Author Statement |
|
F |
Seeded From UniProt |
|||
| GO:0004109 |
coproporphyrinogen oxidase activity |
Reactome:REACT_9421 |
TAS: Traceable Author Statement |
|
F |
Seeded From UniProt |
||
| GO:0005737 |
cytoplasm |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0005739 |
mitochondrion |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005739 |
mitochondrion |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000055455 |
C |
Seeded From UniProt |
|||
| GO:0005739 |
mitochondrion |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000002257 |
C |
Seeded From UniProt |
|||
| GO:0005739 |
mitochondrion |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0005739 |
mitochondrion |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
|||
| GO:0005743 |
mitochondrial inner membrane |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000002257 |
C |
Seeded From UniProt |
|||
| GO:0005758 |
mitochondrial intermembrane space |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000002257 |
C |
Seeded From UniProt |
|||
| GO:0005758 |
mitochondrial intermembrane space |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0169 |
C |
Seeded From UniProt |
|||
| GO:0005758 |
mitochondrial intermembrane space |
Reactome:REACT_9421 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0006778 |
porphyrin-containing compound metabolic process |
Reactome:REACT_9431 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0006779 |
porphyrin-containing compound biosynthetic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006779 |
porphyrin-containing compound biosynthetic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006779 |
porphyrin-containing compound biosynthetic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006782 |
protoporphyrinogen IX biosynthetic process |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000002257 |
P |
Seeded From UniProt |
|||
| GO:0006783 |
heme biosynthetic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006783 |
heme biosynthetic process |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000055455 |
P |
Seeded From UniProt |
|||
| GO:0006783 |
heme biosynthetic process |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000002257 |
P |
Seeded From UniProt |
|||
| GO:0006783 |
heme biosynthetic process |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0006783 |
heme biosynthetic process |
Reactome:REACT_9465 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0010035 |
response to inorganic substance |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000002257 |
P |
Seeded From UniProt |
|||
| GO:0010039 |
response to iron ion |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000002257 |
P |
Seeded From UniProt |
|||
| GO:0010288 |
response to lead ion |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000002257 |
P |
Seeded From UniProt |
|||
| GO:0016491 |
oxidoreductase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0017085 |
response to insecticide |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000002257 |
P |
Seeded From UniProt |
|||
| GO:0042802 |
identical protein binding |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000002257 |
F |
Seeded From UniProt |
|||
| GO:0042803 |
protein homodimerization activity |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0044281 |
small molecule metabolic process |
Reactome:REACT_111217 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0046685 |
response to arsenic-containing substance |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000002257 |
P |
Seeded From UniProt |
|||
| GO:0051597 |
response to methylmercury |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000002257 |
P |
Seeded From UniProt |
|||
| GO:0055114 |
oxidation-reduction process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0055114 |
oxidation-reduction process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0055114 |
oxidation-reduction process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
| |||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Rosipal R et al. (1999) Systematic analysis of coproporphyrinogen oxidase gene defects in hereditary coproporphyria and mutation update. Hum Mutat 13: 44-53 PubMed GONUTS page
- ↑ 2.0 2.1 Barbe L et al. (2008) Toward a confocal subcellular atlas of the human proteome. Mol Cell Proteomics 7: 499-508 PubMed GONUTS page
- ↑ Kohno H et al. (1993) Coproporphyrinogen oxidase. Purification, molecular cloning, and induction of mRNA during erythroid differentiation. J Biol Chem 268: 21359-63 PubMed GONUTS page
- ↑ Martasek P et al. (1994) Molecular cloning, sequencing, and functional expression of a cDNA encoding human coproporphyrinogen oxidase. Proc Natl Acad Sci U S A 91: 3024-8 PubMed GONUTS page
- ↑ Lee DS et al. (2005) Structural basis of hereditary coproporphyria. Proc Natl Acad Sci U S A 102: 14232-7 PubMed GONUTS page
