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HUMAN:H2AY
Contents |
| Species (Taxon ID) | Homo sapiens (Human). ([1]) | |
| Gene Name(s) | H2AFY (synonyms: MACROH2A1) | |
| Protein Name(s) | Core histone macro-H2A.1
Histone macroH2A1 mH2A1 Histone H2A.y H2A/y Medulloblastoma antigen MU-MB-50.205 | |
| External Links | ||
| EMBL | AF041483 AF044286 AF054174 AK023409 AC026691 BC013331 BC095406 AY134746 | |
| IPI | IPI00059366 IPI00304171 IPI00744148 | |
| RefSeq | NP_001035248.1 NP_004884.1 NP_613075.1 NP_613258.2 | |
| UniGene | Hs.420272 Hs.599225 | |
| PDB | 1U35 1ZR3 1ZR5 2F8N 2FXK 3HSV 3IID 3IIF 3IVB | |
| PDBsum | 1U35 1ZR3 1ZR5 2F8N 2FXK 3HSV 3IID 3IIF 3IVB | |
| ProteinModelPortal | O75367 | |
| SMR | O75367 | |
| DIP | DIP-44283N | |
| IntAct | O75367 | |
| MINT | MINT-2866965 | |
| STRING | O75367 | |
| PhosphoSite | O75367 | |
| SWISS-2DPAGE | O75367 | |
| PRIDE | O75367 | |
| Ensembl | ENST00000510038 ENST00000511689 | |
| GeneID | 9555 | |
| KEGG | hsa:9555 | |
| UCSC | uc003lam.1 uc003lan.1 | |
| CTD | 9555 | |
| GeneCards | GC05M129857 | |
| HGNC | HGNC:4740 | |
| MIM | 610054 | |
| neXtProt | NX_O75367 | |
| PharmGKB | PA29117 | |
| eggNOG | prNOG11347 | |
| HOVERGEN | HBG009342 | |
| InParanoid | O75367 | |
| OMA | ANDEELH | |
| OrthoDB | EOG4XH00N | |
| PhylomeDB | O75367 | |
| NextBio | 35835 | |
| PMAP-CutDB | O75367 | |
| ArrayExpress | O75367 | |
| Bgee | O75367 | |
| CleanEx | HS_H2AFY | |
| Genevestigator | O75367 | |
| GermOnline | ENSG00000113648 | |
| GO | GO:0001740 GO:0000786 GO:0003677 GO:0016568 GO:0007549 GO:0006334 | |
| InterPro | IPR002589 IPR021171 IPR009072 IPR007125 IPR002119 | |
| Gene3D | G3DSA:1.10.20.10 | |
| Pfam | PF00125 PF01661 | |
| PIRSF | PIRSF037942 | |
| PRINTS | PR00620 | |
| SMART | SM00506 SM00414 | |
| SUPFAM | SSF47113 | |
| PROSITE | PS51154 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000786 |
nucleosome |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0000786 |
nucleosome |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0000786 |
nucleosome |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0000786 |
nucleosome |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000049143 |
C |
Seeded From UniProt |
|||
| GO:0000786 |
nucleosome |
NAS: Non-traceable Author Statement |
|
C |
Seeded From UniProt |
|||
| GO:0000793 |
condensed chromosome |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000016081 |
C |
Seeded From UniProt |
|||
| GO:0001740 |
Barr body |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0003677 |
DNA binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0003677 |
DNA binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0003677 |
DNA binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0003677 |
DNA binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0003677 |
DNA binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0003677 |
DNA binding |
NAS: Non-traceable Author Statement |
|
F |
Seeded From UniProt |
|||
| GO:0003682 |
chromatin binding |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000016081 |
F |
Seeded From UniProt |
|||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000016081 |
C |
Seeded From UniProt |
|||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0191 |
C |
Seeded From UniProt |
|||
| GO:0005694 |
chromosome |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005694 |
chromosome |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0468 |
C |
Seeded From UniProt |
|||
| GO:0006334 |
nucleosome assembly |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006334 |
nucleosome assembly |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006334 |
nucleosome assembly |
NAS: Non-traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0007549 |
dosage compensation |
IDA: Inferred from Direct Assay |
|
P |
Seeded From UniProt |
|||
| GO:0016568 |
chromatin modification |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0000786 |
IDA: Inferred from Direct Assay |
Figure 3 shows that mH2A regulates the gene CDK8 |
complete | |||||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Lee Y et al. (1998) Isolation of cDNA clones encoding human histone macroH2A1 subtypes. Biochim Biophys Acta 1399: 73-7 PubMed GONUTS page
- ↑ Chadwick BP & Willard HF (2001) Histone H2A variants and the inactive X chromosome: identification of a second macroH2A variant. Hum Mol Genet 10: 1101-13 PubMed GONUTS page
- ↑ Acín-Pérez R et al. (2004) Respiratory complex III is required to maintain complex I in mammalian mitochondria. Mol Cell 13: 805-15 PubMed GONUTS page
- ↑ Kapoor A et al. (2010) The histone variant macroH2A suppresses melanoma progression through regulation of CDK8. Nature 468: 1105-9 PubMed GONUTS page
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