![]()
GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
HUMAN:GSTO2
Contents |
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | GSTO2 | |
| Protein Name(s) | Glutathione S-transferase omega-2
GSTO-2 Glutathione S-transferase omega 2-2 GSTO 2-2 Glutathione-dependent dehydroascorbate reductase Monomethylarsonic acid reductase MMA(V) reductase | |
| External Links | ||
| UniProt | Q9H4Y5 | |
| EMBL | AY350731 AY209189 AK291886 AL162742 BC056918 AY191318 | |
| IPI | IPI00007512 | |
| RefSeq | NP_001177942.1 NP_001177943.1 NP_001177944.1 NP_899062.1 | |
| UniGene | Hs.203634 | |
| ProteinModelPortal | Q9H4Y5 | |
| SMR | Q9H4Y5 | |
| STRING | Q9H4Y5 | |
| DMDM | 34922124 | |
| PRIDE | Q9H4Y5 | |
| Ensembl | ENST00000338595 ENST00000369708 ENST00000401888 | |
| GeneID | 119391 | |
| KEGG | hsa:119391 | |
| UCSC | uc001kyb.1 | |
| CTD | 119391 | |
| GeneCards | GC10P106018 | |
| H-InvDB | HIX0018455 | |
| HGNC | HGNC:23064 | |
| MIM | 612314 | |
| neXtProt | NX_Q9H4Y5 | |
| PharmGKB | PA133787053 | |
| eggNOG | prNOG10020 | |
| GeneTree | ENSGT00390000005479 | |
| HOGENOM | HBG714248 | |
| HOVERGEN | HBG051853 | |
| InParanoid | Q9H4Y5 | |
| OMA | IACEYLD | |
| OrthoDB | EOG43TZW5 | |
| PhylomeDB | Q9H4Y5 | |
| BRENDA | 2.5.1.18 | |
| Reactome | REACT_111217 | |
| DrugBank | DB00143 | |
| NextBio | 80409 | |
| ArrayExpress | Q9H4Y5 | |
| Bgee | Q9H4Y5 | |
| CleanEx | HS_GSTO2 | |
| Genevestigator | Q9H4Y5 | |
| GermOnline | ENSG00000065621 | |
| GO | GO:0005829 GO:0004364 GO:0006767 GO:0006805 | |
| InterPro | IPR010987 IPR004045 IPR017933 IPR005442 IPR012336 | |
| Gene3D | G3DSA:1.20.1050.10 G3DSA:3.40.30.10 | |
| KO | K00799 | |
| Pfam | PF02798 | |
| PRINTS | PR01625 | |
| SUPFAM | SSF47616 SSF52833 | |
| PROSITE | PS50405 PS50404 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004364 |
glutathione transferase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004364 |
glutathione transferase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004364 |
glutathione transferase activity |
Reactome:REACT_6854 |
TAS: Traceable Author Statement |
|
F |
Seeded From UniProt |
||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005829 |
cytosol |
Reactome:REACT_11095 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0005829 |
cytosol |
Reactome:REACT_6854 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0006766 |
vitamin metabolic process |
Reactome:REACT_11193 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0006767 |
water-soluble vitamin metabolic process |
Reactome:REACT_11238 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0006805 |
xenobiotic metabolic process |
IDA: Inferred from Direct Assay |
|
P |
Seeded From UniProt |
|||
| GO:0006805 |
xenobiotic metabolic process |
Reactome:REACT_13433 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0006805 |
xenobiotic metabolic process |
Reactome:REACT_6959 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0008152 |
metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0016491 |
oxidoreductase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0016491 |
oxidoreductase activity |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0016740 |
transferase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0019852 |
L-ascorbic acid metabolic process |
IDA: Inferred from Direct Assay |
|
P |
Seeded From UniProt |
|||
| GO:0019852 |
L-ascorbic acid metabolic process |
Reactome:REACT_11202 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0044281 |
small molecule metabolic process |
Reactome:REACT_111217 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0045174 |
glutathione dehydrogenase (ascorbate) activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0045174 |
glutathione dehydrogenase (ascorbate) activity |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0050610 |
methylarsonate reductase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0055114 |
oxidation-reduction process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0055114 |
oxidation-reduction process |
IDA: Inferred from Direct Assay |
|
P |
Seeded From UniProt |
|||
| GO:0071243 |
cellular response to arsenic-containing substance |
IDA: Inferred from Direct Assay |
|
P |
Seeded From UniProt |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Schmuck EM et al. (2005) Characterization of the monomethylarsonate reductase and dehydroascorbate reductase activities of Omega class glutathione transferase variants: implications for arsenic metabolism and the age-at-onset of Alzheimer's and Parkinson's diseases. Pharmacogenet Genomics 15: 493-501 PubMed GONUTS page