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HUMAN:GSTO2

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Contents

Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) GSTO2
Protein Name(s) Glutathione S-transferase omega-2

GSTO-2 Glutathione S-transferase omega 2-2 GSTO 2-2 Glutathione-dependent dehydroascorbate reductase Monomethylarsonic acid reductase MMA(V) reductase

External Links
UniProt Q9H4Y5
EMBL AY350731
AY209189
AK291886
AL162742
BC056918
AY191318
IPI IPI00007512
RefSeq NP_001177942.1
NP_001177943.1
NP_001177944.1
NP_899062.1
UniGene Hs.203634
ProteinModelPortal Q9H4Y5
SMR Q9H4Y5
STRING Q9H4Y5
DMDM 34922124
PRIDE Q9H4Y5
Ensembl ENST00000338595
ENST00000369708
ENST00000401888
GeneID 119391
KEGG hsa:119391
UCSC uc001kyb.1
CTD 119391
GeneCards GC10P106018
H-InvDB HIX0018455
HGNC HGNC:23064
MIM 612314
neXtProt NX_Q9H4Y5
PharmGKB PA133787053
eggNOG prNOG10020
GeneTree ENSGT00390000005479
HOGENOM HBG714248
HOVERGEN HBG051853
InParanoid Q9H4Y5
OMA IACEYLD
OrthoDB EOG43TZW5
PhylomeDB Q9H4Y5
BRENDA 2.5.1.18
Reactome REACT_111217
DrugBank DB00143
NextBio 80409
ArrayExpress Q9H4Y5
Bgee Q9H4Y5
CleanEx HS_GSTO2
Genevestigator Q9H4Y5
GermOnline ENSG00000065621
GO GO:0005829
GO:0004364
GO:0006767
GO:0006805
InterPro IPR010987
IPR004045
IPR017933
IPR005442
IPR012336
Gene3D G3DSA:1.20.1050.10
G3DSA:3.40.30.10
KO K00799
Pfam PF02798
PRINTS PR01625
SUPFAM SSF47616
SSF52833
PROSITE PS50405
PS50404

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004364

glutathione transferase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005442

F

Seeded From UniProt

GO:0004364

glutathione transferase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.5.1.18

F

Seeded From UniProt

GO:0004364

glutathione transferase activity

Reactome:REACT_6854

TAS: Traceable Author Statement

F

Seeded From UniProt

GO:0005737

cytoplasm

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005442

C

Seeded From UniProt

GO:0005829

cytosol

Reactome:REACT_11095

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005829

cytosol

Reactome:REACT_6854

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0006766

vitamin metabolic process

Reactome:REACT_11193

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0006767

water-soluble vitamin metabolic process

Reactome:REACT_11238

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0006805

xenobiotic metabolic process

PMID:15970797[1]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

GO:0006805

xenobiotic metabolic process

Reactome:REACT_13433

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0006805

xenobiotic metabolic process

Reactome:REACT_6959

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0008152

metabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005442

P

Seeded From UniProt

GO:0016491

oxidoreductase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0560

F

Seeded From UniProt

GO:0016491

oxidoreductase activity

PMID:15970797[1]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

GO:0016740

transferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded From UniProt

GO:0019852

L-ascorbic acid metabolic process

PMID:15970797[1]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

GO:0019852

L-ascorbic acid metabolic process

Reactome:REACT_11202

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0044281

small molecule metabolic process

Reactome:REACT_111217

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0045174

glutathione dehydrogenase (ascorbate) activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:1.8.5.1

F

Seeded From UniProt

GO:0045174

glutathione dehydrogenase (ascorbate) activity

PMID:15970797[1]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

GO:0050610

methylarsonate reductase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:1.20.4.2

F

Seeded From UniProt

GO:0055114

oxidation-reduction process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0560

P

Seeded From UniProt

GO:0055114

oxidation-reduction process

PMID:15970797[1]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

GO:0071243

cellular response to arsenic-containing substance

PMID:15970797[1]

IDA: Inferred from Direct Assay

P

Seeded From UniProt


Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Schmuck EM et al. (2005) Characterization of the monomethylarsonate reductase and dehydroascorbate reductase activities of Omega class glutathione transferase variants: implications for arsenic metabolism and the age-at-onset of Alzheimer's and Parkinson's diseases. Pharmacogenet Genomics 15: 493-501 PubMed GONUTS page
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