Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

HUMAN:FIBG

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) FGG
Protein Name(s) Fibrinogen gamma chain
External Links
UniProt P02679
EMBL M10014
M10014
AF118092
AF350254
AF350254
AK289422
AK290824
BT007081
CH471056
CH471056
BC007044
BC021674
X51473
X00086
K02569
K02569
IPI IPI00021891
IPI00219713
PIR A90470
A90494
RefSeq NP_000500.2
NP_068656.2
UniGene Hs.713625
PDB 1DUG
1FIB
1FIC
1FID
1FZA
1FZB
1FZC
1FZE
1FZF
1FZG
1LT9
1LTJ
1N86
1N8E
1RE3
1RE4
1RF0
1RF1
2A45
2FFD
2FIB
2H43
2HLO
2HOD
2HPC
2HWL
2OYH
2OYI
2Q9I
2VDO
2VDP
2VDQ
2VDR
2VR3
2XNX
2XNY
2Y7L
2Z4E
3BVH
3E1I
3FIB
3GHG
3H32
3HUS
PDBsum 1DUG
1FIB
1FIC
1FID
1FZA
1FZB
1FZC
1FZE
1FZF
1FZG
1LT9
1LTJ
1N86
1N8E
1RE3
1RE4
1RF0
1RF1
2A45
2FFD
2FIB
2H43
2HLO
2HOD
2HPC
2HWL
2OYH
2OYI
2Q9I
2VDO
2VDP
2VDQ
2VDR
2VR3
2XNX
2XNY
2Y7L
2Z4E
3BVH
3E1I
3FIB
3GHG
3H32
3HUS
ProteinModelPortal P02679
SMR P02679
DIP DIP-29644N
IntAct P02679
STRING P02679
DMDM 20178280
SWISS-2DPAGE P02679
Cornea-2DPAGE P02679
DOSAC-COBS-2DPAGE P02679
OGP P02679
REPRODUCTION-2DPAGE IPI00219713
P02679
Siena-2DPAGE P02679
PeptideAtlas P02679
PRIDE P02679
Ensembl ENST00000336098
GeneID 2266
KEGG hsa:2266
UCSC uc003ioj.1
CTD 2266
GeneCards GC04M155525
HGNC HGNC:3694
HPA HPA027529
MIM 134850
202400
neXtProt NX_P02679
Orphanet 98880
98881
248408
101041
PharmGKB PA430
eggNOG prNOG14762
GeneTree ENSGT00600000084261
HOVERGEN HBG099783
PhylomeDB P02679
Pathway_Interaction_DB il6_7pathway
Reactome REACT_111102
REACT_604
DrugBank DB00364
NextBio 9205
PMAP-CutDB P02679
ArrayExpress P02679
Bgee P02679
CleanEx HS_FGG
Genevestigator P02679
GermOnline ENSG00000171557
GO GO:0009897
GO:0005577
GO:0031093
GO:0043499
GO:0030674
GO:0005102
GO:0030168
GO:0002576
GO:0051258
GO:0051592
GO:0007165
InterPro IPR002181
IPR014716
IPR014715
IPR012290
IPR020837
Gene3D G3DSA:3.90.215.10
G3DSA:4.10.530.10
G3DSA:1.20.5.50
KO K03905
Pfam PF08702
PF00147
SMART SM00186
SUPFAM SSF56496
PROSITE PS00514
PS51406

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0002576

platelet degranulation

Reactome:REACT_318

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0005102

receptor binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002181

F

Seeded From UniProt

GO:0005102

receptor binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012290

F

Seeded From UniProt

GO:0005102

receptor binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR014715

F

Seeded From UniProt

GO:0005102

receptor binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR014716

F

Seeded From UniProt

GO:0005576

extracellular region

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0964

C

Seeded From UniProt

GO:0005576

extracellular region

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0243

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_1329

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_13612

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_13787

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_15323

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_15348

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_15349

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_15368

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_15371

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_15375

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_15397

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_15403

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_15405

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_15464

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_15500

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_15535

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_15545

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_1852

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_21351

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_214

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_23775

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_23931

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005576

extracellular region

Reactome:REACT_726

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005577

fibrinogen complex

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012290

C

Seeded From UniProt

GO:0005577

fibrinogen complex

PMID:8470043[1]

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005615

extracellular space

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020837

C

Seeded From UniProt

GO:0005615

extracellular space

PMID:6777381[2]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0005886

plasma membrane

Reactome:REACT_726

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005938

cell cortex

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000126900

C

Seeded From UniProt

GO:0007165

signal transduction

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002181

P

Seeded From UniProt

GO:0007165

signal transduction

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012290

P

Seeded From UniProt

GO:0007165

signal transduction

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR014715

P

Seeded From UniProt

GO:0007165

signal transduction

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR014716

P

Seeded From UniProt

GO:0007596

blood coagulation

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0094

P

Seeded From UniProt

GO:0007596

blood coagulation

Reactome:REACT_1439

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0007596

blood coagulation

Reactome:REACT_2051

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0007596

blood coagulation

Reactome:REACT_604

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0009897

external side of plasma membrane

PMID:6777381[2]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0030168

platelet activation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012290

P

Seeded From UniProt

GO:0030168

platelet activation

Reactome:REACT_798

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0030674

protein binding, bridging

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012290

F

Seeded From UniProt

GO:0031091

platelet alpha granule

PMID:6777381[2]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0031093

platelet alpha granule lumen

Reactome:REACT_21351

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0043499

eukaryotic cell surface binding

PMID:6777381[2]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

GO:0051258

protein polymerization

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012290

P

Seeded From UniProt

GO:0051592

response to calcium ion

PMID:6777381[2]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

GO:0005577

fibrinogen complex

PMID:6451630[3]

IDA: Inferred from Direct Assay

C

Figure 6. Shows the presence of two binding sites for the D1 peptide on the NH-2 terminal region of the fibrin monomer.

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ Rosenberg JB et al. (1993) Paris I dysfibrinogenemia: a point mutation in intron 8 results in insertion of a 15 amino acid sequence in the fibrinogen gamma-chain. Thromb Haemost 69: 217-20 PubMed GONUTS page
  2. ↑ 2.0 2.1 2.2 2.3 2.4 Phillips DR et al. (1980) Ca2+-mediated association of glycoprotein G (thrombinsensitive protein, thrombospondin) with human platelets. J Biol Chem 255: 11629-32 PubMed GONUTS page
  3. ↑ Olexa SA & Budzynski AZ (1981) Localization of a fibrin polymerization site. J Biol Chem 256: 3544-9 PubMed GONUTS page
Retrieved from "http://gowiki.tamu.edu/wiki/index.php/HUMAN:FIBG"
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox