HUMAN:FBW1A

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	BTRC (synonyms: BTRCP, FBW1A, FBXW1A)
Protein Name(s)	F-box/WD repeat-containing protein 1A E3RSIkappaB Epididymis tissue protein Li 2a F-box and WD repeats protein beta-TrCP pIkappaBalpha-E3 receptor subunit
External Links
UniProt	Q9Y297
EMBL	AF101784 Y14153 AF129530 GU727631 AK313353 AL133387 AL445463 AL627424 AL133387 AL445463 AL627424 AL445463 AL133387 AL627424 AL445463 AL133387 AL627424 AL627424 AL133387 AL445463 AL627424 AL133387 AL445463 CH471066 CH471066 BC027994
CCDS	CCDS7511.1 CCDS7512.1
RefSeq	NP_003930.1 NP_378663.1
UniGene	Hs.643802
PDB	1P22 2P64
PDBsum	1P22 2P64
ProteinModelPortal	Q9Y297
SMR	Q9Y297
BioGrid	114457
DIP	DIP-31607N
IntAct	Q9Y297
MINT	MINT-108636
STRING	9606.ENSP00000359206
PhosphoSite	Q9Y297
DMDM	13124271
MaxQB	Q9Y297
PaxDb	Q9Y297
PRIDE	Q9Y297
DNASU	8945
Ensembl	ENST00000370187 ENST00000408038
GeneID	8945
KEGG	hsa:8945
UCSC	uc001kta.4 uc001ktb.4
CTD	8945
GeneCards	GC10P103103
HGNC	HGNC:1144
HPA	CAB032986
MIM	603482
neXtProt	NX_Q9Y297
Orphanet	2440
PharmGKB	PA25465
eggNOG	COG2319
GeneTree	ENSGT00760000119106
HOGENOM	HOG000006638
HOVERGEN	HBG002521
InParanoid	Q9Y297
KO	K03362
OMA	NNDEPPR
OrthoDB	EOG76DTS5
PhylomeDB	Q9Y297
TreeFam	TF105679
Reactome	REACT_11063 REACT_115697 REACT_118656 REACT_160315 REACT_200731 REACT_206597 REACT_22442 REACT_231645 REACT_24941 REACT_267605 REACT_6821 REACT_75842 REACT_9031
SignaLink	Q9Y297
UniPathway	UPA00143
ChiTaRS	BTRC
EvolutionaryTrace	Q9Y297
GeneWiki	BTRC_(gene)
GenomeRNAi	8945
NextBio	33645
PRO	PR:Q9Y297
Proteomes	UP000005640
Bgee	Q9Y297
CleanEx	HS_BTRC
ExpressionAtlas	Q9Y297
Genevestigator	Q9Y297
GO	GO:0005829 GO:0005634 GO:0019005 GO:0016874 GO:0004842 GO:0031145 GO:0060444 GO:0071407 GO:0000086 GO:0033598 GO:0000278 GO:0043433 GO:0045879 GO:0045892 GO:0042753 GO:0045862 GO:0045893 GO:0051437 GO:0043161 GO:0006470 GO:0031648 GO:0000209 GO:0016567 GO:0051726 GO:0042752 GO:0043122 GO:0061136 GO:0051439 GO:0048511 GO:0031146 GO:0007165 GO:0006511 GO:0016032 GO:0016055
Gene3D	2.130.10.10
InterPro	IPR021977 IPR001810 IPR020472 IPR015943 IPR001680 IPR019775 IPR017986
Pfam	PF12125 PF12937 PF00400
PRINTS	PR00320
SMART	SM01028 SM00256 SM00320
SUPFAM	SSF50978 SSF81383
PROSITE	PS50181 PS00678 PS50082 PS50294

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0016567	protein ubiquitination	PMID:18354482^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0016567	protein ubiquitination	PMID:21258371^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	PMID:21911472^[3]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q3ULA2	P		Seeded From UniProt	complete
involved_in	GO:0060828	regulation of canonical Wnt signaling pathway	PMID:12820959^[4]	ECO:0000305	curator inference used in manual assertion	GO:0000209,GO:0008013	P		Seeded From UniProt	complete
contributes_to	GO:0061630	ubiquitin protein ligase activity	PMID:12820959^[4]	ECO:0000314	direct assay evidence used in manual assertion		F	has_direct_input:(UniProtKB:P35222)	Seeded From UniProt	complete
involved_in	GO:0000209	protein polyubiquitination	PMID:12820959^[4]	ECO:0000314	direct assay evidence used in manual assertion		P	has_direct_input:(UniProtKB:P35222)	Seeded From UniProt	complete
enables	GO:0008013	beta-catenin binding	PMID:12820959^[4]	ECO:0000314	direct assay evidence used in manual assertion		F	has_direct_input:(UniProtKB:P35222)	Seeded From UniProt	complete
involved_in	GO:0000209	protein polyubiquitination	PMID:12820959^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	has_direct_input:(UniProtKB:P25963)	Seeded From UniProt	complete
part_of	GO:0019005	SCF ubiquitin ligase complex	PMID:12820959^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q3ULA2	P		Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	PMID:19966869^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045862	positive regulation of proteolysis	PMID:16885022^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	PMID:15917222^[7]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0042753	positive regulation of circadian rhythm	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q3ULA2	P		Seeded From UniProt	complete
involved_in	GO:0042752	regulation of circadian rhythm	PMID:15917222^[7]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0031648	protein destabilization	PMID:16885022^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0019005	SCF ubiquitin ligase complex	PMID:19966869^[5]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0016567	protein ubiquitination	PMID:16885022^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006511	ubiquitin-dependent protein catabolic process	PMID:15448698^[8]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006470	protein dephosphorylation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q3ULA2	P		Seeded From UniProt	complete
contributes_to	GO:0004842	ubiquitin-protein transferase activity	PMID:15448698^[8]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome	PMID:21873635^[9]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000457905 SGD:S000004212	C		Seeded From UniProt	complete
part_of	GO:0032040	small-subunit processome	PMID:21873635^[9]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000457905 SGD:S000004212 UniProtKB:A0A1D8PNG5	C		Seeded From UniProt	complete
involved_in	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	PMID:21873635^[9]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000457905 SGD:S000004212	P		Seeded From UniProt	complete
involved_in	GO:0071407	cellular response to organic cyclic compound	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q3ULA2 ensembl:ENSMUSP00000070728	P		Seeded From UniProt	complete
enables	GO:0061630	ubiquitin protein ligase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q3ULA2 ensembl:ENSMUSP00000070728	F		Seeded From UniProt	complete
involved_in	GO:0061136	regulation of proteasomal protein catabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q3ULA2 ensembl:ENSMUSP00000070728	P		Seeded From UniProt	complete
involved_in	GO:0060828	regulation of canonical Wnt signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q3ULA2 ensembl:ENSMUSP00000070728	P		Seeded From UniProt	complete
involved_in	GO:0060444	branching involved in mammary gland duct morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q3ULA2 ensembl:ENSMUSP00000070728	P		Seeded From UniProt	complete
involved_in	GO:0051726	regulation of cell cycle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q3ULA2 ensembl:ENSMUSP00000070728	P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q3ULA2 ensembl:ENSMUSP00000070728	P		Seeded From UniProt	complete
enables	GO:0045309	protein phosphorylated amino acid binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q3ULA2 ensembl:ENSMUSP00000070728	F		Seeded From UniProt	complete
involved_in	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q3ULA2 ensembl:ENSMUSP00000070728	P		Seeded From UniProt	complete
involved_in	GO:0042753	positive regulation of circadian rhythm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q3ULA2 ensembl:ENSMUSP00000070728	P		Seeded From UniProt	complete
involved_in	GO:0033598	mammary gland epithelial cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q3ULA2 ensembl:ENSMUSP00000070728	P		Seeded From UniProt	complete
involved_in	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q3ULA2 ensembl:ENSMUSP00000070728	P		Seeded From UniProt	complete
involved_in	GO:0030163	protein catabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q3ULA2 ensembl:ENSMUSP00000070728	P		Seeded From UniProt	complete
enables	GO:0008013	beta-catenin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q3ULA2 ensembl:ENSMUSP00000070728	F		Seeded From UniProt	complete
involved_in	GO:0006470	protein dephosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q3ULA2 ensembl:ENSMUSP00000070728	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q3ULA2 ensembl:ENSMUSP00000070728	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q3ULA2 ensembl:ENSMUSP00000070728	C		Seeded From UniProt	complete
involved_in	GO:0000209	protein polyubiquitination	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q3ULA2 ensembl:ENSMUSP00000070728	P		Seeded From UniProt	complete
enables	GO:0046983	protein dimerization activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR021977	F		Seeded From UniProt	complete
involved_in	GO:0007165	signal transduction	PMID:9990853^[10]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006511	ubiquitin-dependent protein catabolic process	PMID:9990853^[10]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045879	negative regulation of smoothened signaling pathway	PMID:11001584^[11]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0043433	negative regulation of DNA-binding transcription factor activity	PMID:11001584^[11]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	has_regulation_target:(UniProtKB:P08151)	Seeded From UniProt	complete
involved_in	GO:1901990	regulation of mitotic cell cycle phase transition	Reactome:R-HSA-174113	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0070498	interleukin-1-mediated signaling pathway	Reactome:R-HSA-9020702	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0051403	stress-activated MAPK cascade	Reactome:R-HSA-450294	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0050852	T cell receptor signaling pathway	Reactome:R-HSA-202403	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0043687	post-translational protein modification	Reactome:R-HSA-597592	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0038095	Fc-epsilon receptor signaling pathway	Reactome:R-HSA-2454202	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0038061	NIK/NF-kappaB signaling	Reactome:R-HSA-5676590	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0016055	Wnt signaling pathway	Reactome:R-HSA-195721	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	Reactome:R-HSA-983157 Reactome:R-HSA-983156 Reactome:R-HSA-983147 Reactome:R-HSA-983140 Reactome:R-HSA-8956200 Reactome:R-HSA-8956040 Reactome:R-HSA-8955289 Reactome:R-HSA-8955241 Reactome:R-HSA-8952620 Reactome:R-HSA-8952618 Reactome:R-HSA-5684250 Reactome:R-HSA-5684248 Reactome:R-HSA-5610746 Reactome:R-HSA-5610742 Reactome:R-HSA-5607728 Reactome:R-HSA-5607725 Reactome:R-HSA-5607723 Reactome:R-HSA-3000339 Reactome:R-HSA-3000335 Reactome:R-HSA-2130286 Reactome:R-HSA-2130282 Reactome:R-HSA-2130279 Reactome:R-HSA-209125 Reactome:R-HSA-209063 Reactome:R-HSA-180599 Reactome:R-HSA-180597 Reactome:R-HSA-180591 Reactome:R-HSA-180573 Reactome:R-HSA-174209 Reactome:R-HSA-174203 Reactome:R-HSA-174159 Reactome:R-HSA-1370500 Reactome:R-HSA-1170539 Reactome:R-HSA-1168643 Reactome:R-HSA-1168642	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	Reactome:R-HSA-3364042 Reactome:R-HSA-3361751	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0002223	stimulatory C-type lectin receptor signaling pathway	Reactome:R-HSA-5621481	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0000209	protein polyubiquitination	Reactome:R-HSA-983168	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0000086	G2/M transition of mitotic cell cycle	Reactome:R-HSA-69275	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
involved_in	GO:0016032	viral process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0945	P		Seeded From UniProt	complete
involved_in	GO:0048511	rhythmic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0090	P		Seeded From UniProt	complete
enables	GO:0016874	ligase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0436	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
involved_in	GO:0016055	Wnt signaling pathway	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0879	P		Seeded From UniProt	complete
involved_in	GO:0016567	protein ubiquitination	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00143	P		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Guardavaccaro, D et al. (2008) Control of chromosome stability by the beta-TrCP-REST-Mad2 axis. Nature 452 365-9 PubMed GONUTS page
↑ Huang, Z et al. (2011) Deubiquitylase HAUSP stabilizes REST and promotes maintenance of neural progenitor cells. Nat. Cell Biol. 13 142-52 PubMed GONUTS page
↑ Tsuchiya, Y et al. (2011) Dual regulation of the transcriptional activity of Nrf1 by β-TrCP- and Hrd1-dependent degradation mechanisms. Mol. Cell. Biol. 31 4500-12 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 Wu, G et al. (2003) Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase. Mol. Cell 11 1445-56 PubMed GONUTS page
↑ ^5.0 ^5.1 Peschiaroli, A et al. (2010) The ubiquitin-specific protease USP47 is a novel beta-TRCP interactor regulating cell survival. Oncogene 29 1384-93 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 Peschiaroli, A et al. (2006) SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response. Mol. Cell 23 319-29 PubMed GONUTS page
↑ ^7.0 ^7.1 Shirogane, T et al. (2005) SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein. J. Biol. Chem. 280 26863-72 PubMed GONUTS page
↑ ^8.0 ^8.1 Zhou, BP et al. (2004) Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition. Nat. Cell Biol. 6 931-40 PubMed GONUTS page
↑ ^9.0 ^9.1 ^9.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^10.0 ^10.1 Spencer, E et al. (1999) Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP. Genes Dev. 13 284-94 PubMed GONUTS page
↑ ^11.0 ^11.1 Villavicencio, EH et al. (2000) The sonic hedgehog-patched-gli pathway in human development and disease. Am. J. Hum. Genet. 67 1047-54 PubMed GONUTS page

[PMID:18354482-1] Guardavaccaro, D et al. (2008) Control of chromosome stability by the beta-TrCP-REST-Mad2 axis. Nature 452 365-9 PubMed GONUTS page

[PMID:21258371-2] Huang, Z et al. (2011) Deubiquitylase HAUSP stabilizes REST and promotes maintenance of neural progenitor cells. Nat. Cell Biol. 13 142-52 PubMed GONUTS page

[PMID:21911472-3] Tsuchiya, Y et al. (2011) Dual regulation of the transcriptional activity of Nrf1 by β-TrCP- and Hrd1-dependent degradation mechanisms. Mol. Cell. Biol. 31 4500-12 PubMed GONUTS page

[PMID:12820959-4] 4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 Wu, G et al. (2003) Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase. Mol. Cell 11 1445-56 PubMed GONUTS page

[PMID:19966869-5] 5.0 ^5.1 Peschiaroli, A et al. (2010) The ubiquitin-specific protease USP47 is a novel beta-TRCP interactor regulating cell survival. Oncogene 29 1384-93 PubMed GONUTS page

[PMID:16885022-6] 6.0 ^6.1 ^6.2 Peschiaroli, A et al. (2006) SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response. Mol. Cell 23 319-29 PubMed GONUTS page

[PMID:15917222-7] 7.0 ^7.1 Shirogane, T et al. (2005) SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein. J. Biol. Chem. 280 26863-72 PubMed GONUTS page

[PMID:15448698-8] 8.0 ^8.1 Zhou, BP et al. (2004) Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition. Nat. Cell Biol. 6 931-40 PubMed GONUTS page

[PMID:21873635-9] 9.0 ^9.1 ^9.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:9990853-10] 10.0 ^10.1 Spencer, E et al. (1999) Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP. Genes Dev. 13 284-94 PubMed GONUTS page

[PMID:11001584-11] 11.0 ^11.1 Villavicencio, EH et al. (2000) The sonic hedgehog-patched-gli pathway in human development and disease. Am. J. Hum. Genet. 67 1047-54 PubMed GONUTS page

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HUMAN:FBW1A

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