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HUMAN:EFNB1
Contents |
| Species (Taxon ID) | Homo sapiens (Human). ([1]) | |
| Gene Name(s) | EFNB1 (synonyms: EFL3, EPLG2, LERK2) | |
| Protein Name(s) | Ephrin-B1
EFL-3 ELK ligand ELK-L EPH-related receptor tyrosine kinase ligand 2 LERK-2 | |
| External Links | ||
| EMBL | U09304 L37361 U09303 AL136092 CH471132 CH471132 BC016649 BC052979 | |
| IPI | IPI00024307 | |
| PIR | S46993 | |
| RefSeq | NP_004420.1 | |
| UniGene | Hs.144700 | |
| ProteinModelPortal | P98172 | |
| SMR | P98172 | |
| IntAct | P98172 | |
| STRING | P98172 | |
| PhosphoSite | P98172 | |
| PeptideAtlas | P98172 | |
| PRIDE | P98172 | |
| Ensembl | ENST00000204961 | |
| GeneID | 1947 | |
| KEGG | hsa:1947 | |
| UCSC | uc004dxd.2 | |
| CTD | 1947 | |
| GeneCards | GC0XP061874 | |
| H-InvDB | HIX0016846 | |
| HGNC | HGNC:3226 | |
| HPA | CAB031489 | |
| MIM | 300035 304110 | |
| neXtProt | NX_P98172 | |
| Orphanet | 1520 | |
| PharmGKB | PA27661 | |
| eggNOG | prNOG10511 | |
| GeneTree | ENSGT00390000005839 | |
| HOGENOM | HBG443543 | |
| HOVERGEN | HBG051448 | |
| InParanoid | P98172 | |
| OMA | MATQAPG | |
| OrthoDB | EOG4W3SNT | |
| PhylomeDB | P98172 | |
| Pathway_Interaction_DB | ephbfwdpathway ephrinbrevpathway ephrinb_ephbpathway | |
| NextBio | 7891 | |
| PMAP-CutDB | P98172 | |
| ArrayExpress | P98172 | |
| Bgee | P98172 | |
| CleanEx | HS_EFNB1 | |
| Genevestigator | P98172 | |
| GermOnline | ENSG00000090776 | |
| GO | GO:0005887 GO:0005625 GO:0045202 GO:0046875 GO:0007155 GO:0007267 | |
| InterPro | IPR008972 IPR001799 IPR019765 | |
| Gene3D | G3DSA:2.60.40.420 | |
| KO | K05463 | |
| PANTHER | PTHR11304 | |
| Pfam | PF00812 | |
| PRINTS | PR01347 | |
| ProDom | PD002533 | |
| SUPFAM | SSF49503 | |
| PROSITE | PS01299 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001755 |
neural crest cell migration |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000050716 |
P |
Seeded From UniProt |
|||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded From UniProt |
||||
| GO:0005625 |
soluble fraction |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
|||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000050716 |
C |
Seeded From UniProt |
|||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000050716 |
C |
Seeded From UniProt |
|||
| GO:0005887 |
integral to plasma membrane |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
|||
| GO:0007155 |
cell adhesion |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0007267 |
cell-cell signaling |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0007275 |
multicellular organismal development |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007399 |
nervous system development |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007399 |
nervous system development |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000009635 |
P |
Seeded From UniProt |
|||
| GO:0007411 |
axon guidance |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000050716 |
P |
Seeded From UniProt |
|||
| GO:0009880 |
embryonic pattern specification |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000050716 |
P |
Seeded From UniProt |
|||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0162 |
C |
Seeded From UniProt |
|||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0030154 |
cell differentiation |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0042102 |
positive regulation of T cell proliferation |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000050716 |
P |
Seeded From UniProt |
|||
| GO:0045121 |
membrane raft |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000050716 |
C |
Seeded From UniProt |
|||
| GO:0045202 |
synapse |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000009635 |
C |
Seeded From UniProt |
|||
| GO:0045202 |
synapse |
ISS: Inferred from Sequence or Structural Similarity |
C |
Seeded From UniProt |
||||
| GO:0046875 |
ephrin receptor binding |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000050716 |
F |
Seeded From UniProt |
|||
| GO:0046875 |
ephrin receptor binding |
TAS: Traceable Author Statement |
|
F |
Seeded From UniProt |
|||
| GO:0046875 |
IDA: Inferred from Direct Assay |
Figure 3 |
complete | |||||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Torres R et al. (1998) PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands. Neuron 21: 1453-63 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Böhme B et al. (1996) Cell-cell adhesion mediated by binding of membrane-anchored ligand LERK-2 to the EPH-related receptor human embryonal kinase 2 promotes tyrosine kinase activity. J Biol Chem 271: 24747-52 PubMed GONUTS page
- ↑ Cerretti DP et al. (1996) The genes encoding the eph-related receptor tyrosine kinase ligands LERK-1 (EPLG1, Epl1), LERK-3 (EPLG3, Epl3), and LERK-4 (EPLG4, Epl4) are clustered on human chromosome 1 and mouse chromosome 3. Genomics 33: 277-82 PubMed GONUTS page
- ↑ Beckmann MP et al. (1994) Molecular characterization of a family of ligands for eph-related tyrosine kinase receptors. EMBO J 13: 3757-62 PubMed GONUTS page
