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HUMAN:DAP1

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Contents

Species (Taxon ID) Homo sapiens (Human). (taxon:9606)
Gene Name(s) DAP ( synonyms: DAP1 )
Protein Name(s)
  • Death-associated protein 1
  • DAP-1
External Links
UniProt Identifier DAP1_HUMAN
UniProt Accessions P51397, Q6FGC3, Q9BUC9,
EMBL X76105, CR542184, AY266680, BC002726,
PIR I37274,
RefSeq NP_004385.1,
IntAct P51397,
Ensembl ENST00000230895,

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0006915

apoptosis

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0053

P

GO:0006919

activation of caspase activity

PMID:1087798[1]

IMP: Inferred from Mutant Phenotype

P

GO:0008624

induction of apoptosis by extracellular signals

PMID:1087798[1]

IMP: Inferred from Mutant Phenotype

P

GO:0008624

induction of apoptosis by extracellular signals

PMID:7828849[2]

IMP: Inferred from Mutant Phenotype

P

GO:0010507

negative regulation of autophagy

PMID:20537536[3]

IMP: Inferred from Mutant Phenotype

P

GO:0016564

transcription repressor activity

PMID:1087798[1]

IMP: Inferred from Mutant Phenotype

F

GO:0032088

negative regulation of NF-kappaB transcription factor activity

PMID:1087798[1]

IMP: Inferred from Mutant Phenotype

P

GO:0034198

cellular response to amino acid starvation

PMID:20537536[3]

IDA: Inferred from Direct Assay

P

GO:0070513

death domain binding

PMID:1087798[1]

IPI: Inferred from Physical Interaction

UniProtKB:P19438

F

GO:0006915

apoptosis

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0053

P

GO:0006919

activation of caspase activity

PMID:1087798[1]

IMP: Inferred from Mutant Phenotype

P

GO:0008624

induction of apoptosis by extracellular signals

PMID:1087798[1]

IMP: Inferred from Mutant Phenotype

P

GO:0008624

induction of apoptosis by extracellular signals

PMID:7828849[2]

IMP: Inferred from Mutant Phenotype

P

GO:0010507

negative regulation of autophagy

PMID:20537536[3]

IMP: Inferred from Mutant Phenotype

P

GO:0032088

negative regulation of NF-kappaB transcription factor activity

PMID:1087798[1]

IMP: Inferred from Mutant Phenotype

P

GO:0034198

cellular response to amino acid starvation

PMID:20537536[3]

IDA: Inferred from Direct Assay

P

GO:0045892

negative regulation of transcription, DNA-dependent

PMID:1087798[1]

IMP: Inferred from Mutant Phenotype

P

GO:0070513

death domain binding

PMID:1087798[1]

IPI: Inferred from Physical Interaction

UniProtKB:P19438

F


Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Belokrylov GA & Zhitnukhin IuL (1976) [Effect of antibodies to rat and human cerebral cortex and white matter on heterologous T- and B-cells]. Zh Mikrobiol Epidemiol Immunobiol 66-70 PubMed GONUTS page
  2. 2.0 2.1 Deiss LP et al. (1995) Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death. Genes Dev 9: 15-30 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Koren I et al. (2010) DAP1, a novel substrate of mTOR, negatively regulates autophagy. Curr Biol 20: 1093-8 PubMed GONUTS page
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