HUMAN:CTNB1

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Species (Taxon ID)	Homo sapiens (Human). (taxon:9606)
Gene Name(s)	CTNNB1 ( synonyms: CTNNB )
Protein Name(s)	Catenin beta-1 Beta-catenin
External Links
UniProt Identifier	CTNB1_HUMAN
UniProt Accessions	P35222, A8K1L7, Q8NEW9, Q8NI94, Q9H391,
EMBL	X87838, Z19054, AF130085, AY463360, AK289932, AC104307, CH471055, BC058926, AY081165, AB062292,
PIR	A38973,
RefSeq	NP_001091679.1, NP_001091680.1, NP_001895.1,
PDB	1G3J, 1JDH, 1JPW, 1LUJ, 1P22, 1QZ7, 1T08, 1TH1, 2G57, 2GL7, 2Z6H, 3DIW, 3FQN, 3FQR,
IntAct	P35222,
Ensembl	ENST00000349496, ENST00000396183, ENST00000396185, ENST00000405570,
Pfam	PF00514,

Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes	Status
	GO:0034747	Axin-APC-beta-catenin-GSK3B complex		IDA: Inferred from Direct Assay		C	Source: UniProtKB
	GO:0030877	beta-catenin destruction complex		IDA: Inferred from Direct Assay		C	Source: UniProtKB
	GO:0070369	beta-catenin-TCF7L2 complex		IDA: Inferred from Direct Assay		C	Source: UniProtKB
	GO:0016342	catenin complex		IDA: Inferred from Direct Assay		C	Source: UniProtKB
	GO:0005813	centrosome		IDA: Inferred from Direct Assay		C	Source: UniProtKB
	GO:0016328	lateral plasma membrane		IDA: Inferred from Direct Assay		C	Source: MGI
	GO:0048471	perinuclear region of cytoplasm		IDA: Inferred from Direct Assay		C	Source: UniProtKB
	GO:0032993	protein-DNA complex		IDA: Inferred from Direct Assay		C	Source: UniProtKB
	GO:0045294	alpha-catenin binding		IPI: Inferred from Physical Interaction		F	Source: UniProtKB
	GO:0050681	androgen receptor binding		NAS: Non-traceable Author Statement		F	Source: UniProtKB
	GO:0045296	cadherin binding		IPI: Inferred from Physical Interaction		F	Source: UniProtKB
	GO:0070411	I-SMAD binding		IPI: Inferred from Physical Interaction		F	Source: UniProtKB
	GO:0019900	kinase binding		IPI: Inferred from Physical Interaction		F	Source: UniProtKB
	GO:0010843	promoter binding		IDA: Inferred from Direct Assay		F	Source: UniProtKB
	GO:0008022	protein C-terminus binding		IPI: Inferred from Physical Interaction		F	Source: UniProtKB
	GO:0019903	protein phosphatase binding		IPI: Inferred from Physical Interaction		F	Source: UniProtKB
	GO:0004871	signal transducer activity		NAS: Non-traceable Author Statement		F	Source: ProtInc
	GO:0003713	transcription coactivator activity		IDA: Inferred from Direct Assay		F	Source: UniProtKB
	GO:0030521	androgen receptor signaling pathway		NAS: Non-traceable Author Statement		P	Source: UniProtKB
	GO:0016337	cell-cell adhesion		IMP: Inferred from Mutant Phenotype		P	Source: UniProtKB
	GO:0071363	cellular response to growth factor stimulus		IMP: Inferred from Mutant Phenotype		P	Source: UniProtKB
	GO:0071681	cellular response to indole-3-methanol		IDA: Inferred from Direct Assay		P	Source: UniProtKB
	GO:0001837	epithelial to mesenchymal transition		TAS: Traceable Author Statement		P	Source: HGNC
	GO:0008285	negative regulation of cell proliferation		IDA: Inferred from Direct Assay		P	Source: UniProtKB
	GO:0043065	positive regulation of apoptosis		IDA: Inferred from Direct Assay		P	Source: UniProtKB
	GO:0010552	positive regulation of gene-specific transc...		IDA: Inferred from Direct Assay		P	Source: UniProtKB
	GO:0010909	positive regulation of heparan sulfate prot...		IMP: Inferred from Mutant Phenotype		P	Source: UniProtKB
	GO:0045765	regulation of angiogenesis		TAS: Traceable Author Statement		P	Source: UniProtKB
	GO:0030997	regulation of centriole-centriole cohesion		IDA: Inferred from Direct Assay		P	Source: UniProtKB
	GO:0048145	regulation of fibroblast proliferation		TAS: Traceable Author Statement		P	Source: UniProtKB
	GO:0042493	response to drug		IEP: Inferred from Expression Pattern		P	Source: UniProtKB
	GO:0006350	transcription		IEA: Inferred from Electronic Annotation		P	Source: UniProtKB-KW
	GO:0060070	Wnt receptor signaling pathway through beta...		IDA: Inferred from Direct Assay		P	Source: UniProtKB
	GO:0019900	kinase binding	PMID:20307497^[1]	IPI: Inferred from Physical Interaction	UniProtKB:Q9H2X6	F	figure S1	complete
	GO:0005634	nucleus	PMID:20307497^[1]	IDA: Inferred from Direct Assay		C	figure 1E	complete
	GO:0005737	cytoplasm	PMID:20307497^[1]	IDA: Inferred from Direct Assay		C	figure 1E	complete
	GO:0016310	phosphorylation	PMID:20307497^[1]	IMP: Inferred from Mutant Phenotype		P	figure 3C	complete
	GO:0000122	negative regulation of transcription from RNA polymerase II promoter	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0005737	cytoplasm	PMID:7806582^[2]	IDA: Inferred from Direct Assay		C	Fig 2B shows cytoplasmic localisation of B catenin through immunofluorescence	complete
	GO:0000122	negative regulation of transcription from RNA polymerase II promoter	GO_REF:0000033		PANTHER:PTHR23315_AN54	P
	GO:0000578	embryonic axis specification	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0000578	embryonic axis specification	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0000904	cell morphogenesis involved in differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0031334	positive regulation of protein complex assembly	PMID:7806582^[2]	IDA: Inferred from Direct Assay		P	Fig 6 shows B catenin mediates cadherin-catenin complex formation	complete
	GO:0001501	skeletal system development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:2000047	regulation of cell-cell adhesion mediated by cadherin	PMID:7806582^[2]	IDA: Inferred from Direct Assay		P	cumulative evidence. fig 6 and 5 show role beta catenin has to play in complex formation and alpha catenin binding. Alpha catenin is a known cell cell adhesion molecule therefore assumptions can be made that beta catenin regulates cell - cell adhesion	complete
	GO:0001569	patterning of blood vessels	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0001569	patterning of blood vessels	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0001569	patterning of blood vessels	PMID:20123964^[3]	IC: Inferred by Curator	GO:0061154	P
	GO:0001570	vasculogenesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0001658	branching involved in ureteric bud morphogenesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0001658	branching involved in ureteric bud morphogenesis	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0001701	in utero embryonic development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0001702	gastrulation with mouth forming second	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0001702	gastrulation with mouth forming second	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0001706	endoderm formation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0001708	cell fate specification	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0001709	cell fate determination	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0001711	endodermal cell fate commitment	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0001711	endodermal cell fate commitment	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0001822	kidney development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0001837	epithelial to mesenchymal transition	PMID:14679171^[4]	TAS: Traceable Author Statement		P
	GO:0001889	liver development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000026016	P
	GO:0001889	liver development	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0002053	positive regulation of mesenchymal cell proliferation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0002089	lens morphogenesis in camera-type eye	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0003136	negative regulation of heart induction by canonical Wnt receptor signaling pathway	GO_REF:0000033		PANTHER:PTHR23315_AN54	P
	GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0003338	metanephros morphogenesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0003677	DNA binding	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	F
	GO:0003682	chromatin binding	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	F
	GO:0003690	double-stranded DNA binding	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	F
	GO:0003700	sequence-specific DNA binding transcription factor activity	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	F
	GO:0003713	transcription coactivator activity	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	F
	GO:0003713	transcription coactivator activity	PMID:11751639^[5]	IDA: Inferred from Direct Assay		F
	GO:0003713	transcription coactivator activity	PMID:12949260^[6]	IMP: Inferred from Mutant Phenotype		F
	GO:0003713	transcription coactivator activity	PMID:9065402^[7]	IDA: Inferred from Direct Assay		F
	GO:0004871	signal transducer activity	PMID:10192393^[8]	NAS: Non-traceable Author Statement		F
	GO:0005198	structural molecule activity	GO_REF:0000033		PANTHER:PTHR23315_AN54	F
	GO:0005488	binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011989	F
	GO:0005488	binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR016024	F
	GO:0005515	protein binding	PMID:10773885^[9]	IPI: Inferred from Physical Interaction	UniProtKB:Q15691	F
	GO:0005515	protein binding	PMID:10825188^[10]	IPI: Inferred from Physical Interaction	UniProtKB:Q9UJU2	F
	GO:0005515	protein binding	PMID:10987273^[11]	IPI: Inferred from Physical Interaction	UniProtKB:P10275	F
	GO:0005515	protein binding	PMID:11401320^[12]	IPI: Inferred from Physical Interaction	UniProtKB:P11362	F
	GO:0005515	protein binding	PMID:11401320^[12]	IPI: Inferred from Physical Interaction	UniProtKB:P12830	F
	GO:0005515	protein binding	PMID:11533658^[13]	IPI: Inferred from Physical Interaction	UniProtKB:P25054	F
	GO:0005515	protein binding	PMID:11590244^[14]	IPI: Inferred from Physical Interaction	UniProtKB:Q9UI47	F
	GO:0005515	protein binding	PMID:11955446^[15]	IPI: Inferred from Physical Interaction	UniProtKB:O00512	F
	GO:0005515	protein binding	PMID:12927518^[16]	IPI: Inferred from Physical Interaction	UniProtKB:P18012	F
	GO:0005515	protein binding	PMID:14600025^[17]	IPI: Inferred from Physical Interaction	UniProtKB:Q9YGY0	F
	GO:0005515	protein binding	PMID:15843474^[18]	IPI: Inferred from Physical Interaction	UniProtKB:Q99966	F
	GO:0005515	protein binding	PMID:16204054^[19]	IPI: Inferred from Physical Interaction	UniProtKB:O43707	F
	GO:0005515	protein binding	PMID:16306047^[20]	IPI: Inferred from Physical Interaction	UniProtKB:P49768	F
	GO:0005515	protein binding	PMID:16306047^[20]	IPI: Inferred from Physical Interaction	UniProtKB:Q9NQB0	F
	GO:0005515	protein binding	PMID:16630820^[21]	IPI: Inferred from Physical Interaction	UniProtKB:Q6P1J9	F
	GO:0005515	protein binding	PMID:16630820^[21]	IPI: Inferred from Physical Interaction	UniProtKB:Q8WVC0	F
	GO:0005515	protein binding	PMID:16858403^[22]	IPI: Inferred from Physical Interaction	UniProtKB:P50402	F
	GO:0005515	protein binding	PMID:16890161^[23]	IPI: Inferred from Physical Interaction	UniProtKB:O15169	F
	GO:0005515	protein binding	PMID:17047063^[24]	IPI: Inferred from Physical Interaction	UniProtKB:Q8WY41	F
	GO:0005515	protein binding	PMID:17220478^[25]	IPI: Inferred from Physical Interaction	UniProtKB:Q92597	F
	GO:0005515	protein binding	PMID:17242191^[26]	IPI: Inferred from Physical Interaction	UniProtKB:O14745	F
	GO:0005515	protein binding	PMID:17242191^[26]	IPI: Inferred from Physical Interaction	UniProtKB:Q15599	F
	GO:0005515	protein binding	PMID:17353931^[27]	IPI: Inferred from Physical Interaction	UniProtKB:Q99623	F
	GO:0005515	protein binding	PMID:17353931^[27]	IPI: Inferred from Physical Interaction	UniProtKB:Q9NSA3	F
	GO:0005515	protein binding	PMID:17513457^[28]	IPI: Inferred from Physical Interaction	UniProtKB:P49023	F
	GO:0005515	protein binding	PMID:17785436^[29]	IPI: Inferred from Physical Interaction	UniProtKB:P33724	F
	GO:0005515	protein binding	PMID:17875931^[30]	IPI: Inferred from Physical Interaction	UniProtKB:Q9H6I2	F
	GO:0005515	protein binding	PMID:18086858^[31]	IPI: Inferred from Physical Interaction	UniProtKB:P51955	F
	GO:0005515	protein binding	PMID:18086858^[31]	IPI: Inferred from Physical Interaction	UniProtKB:Q5TZA2	F
	GO:0005515	protein binding	PMID:18193033^[32]	IPI: Inferred from Physical Interaction	UniProtKB:O60907	F
	GO:0005515	protein binding	PMID:18193033^[32]	IPI: Inferred from Physical Interaction	UniProtKB:Q9BZK7	F
	GO:0005515	protein binding	PMID:18287330^[33]	IPI: Inferred from Physical Interaction	UniProtKB:Q9NSA3	F
	GO:0005515	protein binding	PMID:18456656^[34]	IPI: Inferred from Physical Interaction	UniProtKB:P48431	F
	GO:0005515	protein binding	PMID:18591935^[35]	IPI: Inferred from Physical Interaction	UniProtKB:P23508	F
	GO:0005515	protein binding	PMID:18772112^[36]	IPI: Inferred from Physical Interaction	UniProtKB:Q13761	F
	GO:0005515	protein binding	PMID:19167335^[37]	IPI: Inferred from Physical Interaction	UniProtKB:P08575	F
	GO:0005515	protein binding	PMID:19167335^[37]	IPI: Inferred from Physical Interaction	UniProtKB:P23467	F
	GO:0005515	protein binding	PMID:19167335^[37]	IPI: Inferred from Physical Interaction	UniProtKB:P23470	F
	GO:0005515	protein binding	PMID:19167335^[37]	IPI: Inferred from Physical Interaction	UniProtKB:Q05209	F
	GO:0005515	protein binding	PMID:19167335^[37]	IPI: Inferred from Physical Interaction	UniProtKB:Q12913	F
	GO:0005515	protein binding	PMID:19167335^[37]	IPI: Inferred from Physical Interaction	UniProtKB:Q16827	F
	GO:0005515	protein binding	PMID:19303846^[38]	IPI: Inferred from Physical Interaction	UniProtKB:P49841	F
	GO:0005515	protein binding	PMID:20164195^[39]	IPI: Inferred from Physical Interaction	UniProtKB:Q86VW0	F
	GO:0005515	protein binding	PMID:20360943^[40]	IPI: Inferred from Physical Interaction	UniProtKB:Q9UJU2	F
	GO:0005515	protein binding	PMID:21132015^[41]	IPI: Inferred from Physical Interaction	UniProtKB:Q13308	F
	GO:0005515	protein binding	PMID:7890674^[42]	IPI: Inferred from Physical Interaction	UniProtKB:P25054	F
	GO:0005515	protein binding	PMID:9601641^[43]	IPI: Inferred from Physical Interaction	UniProtKB:O15169	F
	GO:0005515	protein binding	PMID:9632714^[44]	IPI: Inferred from Physical Interaction	UniProtKB:P49768	F
	GO:0005515	protein binding	PMID:9707618^[45]	IPI: Inferred from Physical Interaction	UniProtKB:P25054	F
	GO:0005624	membrane fraction	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	C
	GO:0005634	nucleus	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0539	C
	GO:0005634	nucleus	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	C
	GO:0005634	nucleus	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000026016	C
	GO:0005634	nucleus	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0191	C
	GO:0005634	nucleus	PMID:10980594^[46]	IDA: Inferred from Direct Assay		C
	GO:0005634	nucleus	PMID:16858403^[22]	IDA: Inferred from Direct Assay		C
	GO:0005634	nucleus	PMID:17976063^[47]	IDA: Inferred from Direct Assay		C
	GO:0005634	nucleus	PMID:18029348^[48]	IDA: Inferred from Direct Assay		C
	GO:0005634	nucleus	PMID:18193033^[32]	IDA: Inferred from Direct Assay		C
	GO:0005634	nucleus	PMID:18756595^[49]	IDA: Inferred from Direct Assay		C
	GO:0005634	nucleus	PMID:18787224^[50]	IDA: Inferred from Direct Assay		C
	GO:0005634	nucleus	PMID:19095296^[51]	IDA: Inferred from Direct Assay		C
	GO:0005634	nucleus	PMID:19187541^[52]	IDA: Inferred from Direct Assay		C
	GO:0005634	nucleus	PMID:9707618^[45]	IDA: Inferred from Direct Assay		C
	GO:0005667	transcription factor complex	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	C
	GO:0005667	transcription factor complex	PMID:11751639^[5]	IDA: Inferred from Direct Assay		C
	GO:0005737	cytoplasm	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0963	C
	GO:0005737	cytoplasm	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	C
	GO:0005737	cytoplasm	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0086	C
	GO:0005737	cytoplasm	PMID:11793365^[53]	IDA: Inferred from Direct Assay		C
	GO:0005737	cytoplasm	PMID:12937339^[54]	IDA: Inferred from Direct Assay		C
	GO:0005737	cytoplasm	PMID:12970740^[55]	IDA: Inferred from Direct Assay		C
	GO:0005737	cytoplasm	PMID:17976063^[47]	IDA: Inferred from Direct Assay		C
	GO:0005737	cytoplasm	PMID:18029348^[48]	IDA: Inferred from Direct Assay		C
	GO:0005737	cytoplasm	PMID:18787224^[50]	IDA: Inferred from Direct Assay		C
	GO:0005737	cytoplasm	PMID:19095296^[51]	IDA: Inferred from Direct Assay		C
	GO:0005737	cytoplasm	PMID:9707618^[45]	IDA: Inferred from Direct Assay		C
	GO:0005813	centrosome	PMID:18086858^[31]	IDA: Inferred from Direct Assay		C
	GO:0005813	centrosome	PMID:20300119^[56]	IDA: Inferred from Direct Assay		C
	GO:0005829	cytosol	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	C
	GO:0005829	cytosol	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000026016	C
	GO:0005829	cytosol	PMID:10980594^[46]	IDA: Inferred from Direct Assay		C
	GO:0005829	cytosol	PMID:19187541^[52]	IDA: Inferred from Direct Assay		C
	GO:0005829	cytosol	Reactome:REACT_10017	TAS: Traceable Author Statement		C
	GO:0005829	cytosol	Reactome:REACT_10082	TAS: Traceable Author Statement		C
	GO:0005829	cytosol	Reactome:REACT_10127	TAS: Traceable Author Statement		C
	GO:0005829	cytosol	Reactome:REACT_12022	TAS: Traceable Author Statement		C
	GO:0005829	cytosol	Reactome:REACT_21288	TAS: Traceable Author Statement		C
	GO:0005829	cytosol	Reactome:REACT_21371	TAS: Traceable Author Statement		C
	GO:0005829	cytosol	Reactome:REACT_9955	TAS: Traceable Author Statement		C
	GO:0005829	cytosol	Reactome:REACT_9959	TAS: Traceable Author Statement		C
	GO:0005829	cytosol	Reactome:REACT_9977	TAS: Traceable Author Statement		C
	GO:0005829	cytosol	Reactome:REACT_9978	TAS: Traceable Author Statement		C
	GO:0005829	cytosol	Reactome:REACT_9983	TAS: Traceable Author Statement		C
	GO:0005829	cytosol	Reactome:REACT_9987	TAS: Traceable Author Statement		C
	GO:0005856	cytoskeleton	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0206	C
	GO:0005856	cytoskeleton	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0090	C
	GO:0005886	plasma membrane	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-1003	C
	GO:0005886	plasma membrane	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	C
	GO:0005886	plasma membrane	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0039	C
	GO:0005886	plasma membrane	PMID:12970740^[55]	IDA: Inferred from Direct Assay		C
	GO:0005886	plasma membrane	PMID:17976063^[47]	IDA: Inferred from Direct Assay		C
	GO:0005886	plasma membrane	PMID:18029348^[48]	IDA: Inferred from Direct Assay		C
	GO:0005911	cell-cell junction	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	C
	GO:0005911	cell-cell junction	PMID:19151727^[57]	IDA: Inferred from Direct Assay		C
	GO:0005911	cell-cell junction	PMID:19996314^[58]	IDA: Inferred from Direct Assay		C
	GO:0005912	adherens junction	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	C
	GO:0005912	adherens junction	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0009	C
	GO:0005912	adherens junction	PMID:16858403^[22]	IDA: Inferred from Direct Assay		C
	GO:0005913	cell-cell adherens junction	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	C
	GO:0005913	cell-cell adherens junction	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000026016	C
	GO:0005913	cell-cell adherens junction	PMID:10403777^[59]	IDA: Inferred from Direct Assay		C
	GO:0005913	cell-cell adherens junction	PMID:18086858^[31]	IDA: Inferred from Direct Assay		C
	GO:0005913	cell-cell adherens junction	PMID:19101069^[60]	IDA: Inferred from Direct Assay		C
	GO:0005913	cell-cell adherens junction	PMID:20086044^[61]	IDA: Inferred from Direct Assay		C
	GO:0005915	zonula adherens	GO_REF:0000033		PANTHER:PTHR23315_AN54	C
	GO:0005916	fascia adherens	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	C
	GO:0005916	fascia adherens	GO_REF:0000033		PANTHER:PTHR23315_AN54	C
	GO:0005924	cell-substrate adherens junction	PMID:20399743^[62]	IDA: Inferred from Direct Assay		C
	GO:0005938	cell cortex	PMID:19038973^[63]	IDA: Inferred from Direct Assay		C
	GO:0006351	transcription, DNA-dependent	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0804	P
	GO:0006351	transcription, DNA-dependent	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0006355	regulation of transcription, DNA-dependent	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0805	P
	GO:0006355	regulation of transcription, DNA-dependent	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0006915	apoptosis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0006915	apoptosis	Reactome:REACT_578	TAS: Traceable Author Statement		P
	GO:0006921	cellular component disassembly involved in apoptosis	Reactome:REACT_995	TAS: Traceable Author Statement		P
	GO:0007016	cytoskeletal anchoring at plasma membrane	GO_REF:0000033		PANTHER:PTHR23315_AN54	P
	GO:0007155	cell adhesion	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0130	P
	GO:0007155	cell adhesion	PMID:19101069^[60]	IMP: Inferred from Mutant Phenotype		P
	GO:0007160	cell-matrix adhesion	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0007160	cell-matrix adhesion	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0007268	synaptic transmission	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0007398	ectoderm development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0007398	ectoderm development	GO_REF:0000033		PANTHER:PTHR23315_AN57	P
	GO:0007403	glial cell fate determination	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0007403	glial cell fate determination	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0007494	midgut development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000026016	P
	GO:0007507	heart development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0008022	protein C-terminus binding	PMID:10773885^[9]	IPI: Inferred from Physical Interaction	UniProtKB:P25054	F
	GO:0008022	protein C-terminus binding	PMID:15843474^[18]	IPI: Inferred from Physical Interaction	UniProtKB:Q09472	F
	GO:0008134	transcription factor binding	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	F
	GO:0008134	transcription factor binding	PMID:16344550^[64]	TAS: Traceable Author Statement		F
	GO:0008134	transcription factor binding	PMID:20123964^[3]	IPI: Inferred from Physical Interaction	UniProtKB:Q9UJU2	F
	GO:0008283	cell proliferation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0008284	positive regulation of cell proliferation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0008285	negative regulation of cell proliferation	PMID:12970740^[55]	IDA: Inferred from Direct Assay		P
	GO:0009725	response to hormone stimulus	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000026016	P
	GO:0009898	internal side of plasma membrane	GO_REF:0000033		PANTHER:PTHR23315_AN54	C
	GO:0009948	anterior/posterior axis specification	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0009950	dorsal/ventral axis specification	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0009950	dorsal/ventral axis specification	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0009953	dorsal/ventral pattern formation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0009954	proximal/distal pattern formation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0009954	proximal/distal pattern formation	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0009987	cellular process	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0010628	positive regulation of gene expression	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0010909	positive regulation of heparan sulfate proteoglycan biosynthetic process	PMID:15853773^[65]	IMP: Inferred from Mutant Phenotype		P
	GO:0014010	Schwann cell proliferation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000026016	P
	GO:0014010	Schwann cell proliferation	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0014070	response to organic cyclic compound	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000026016	P
	GO:0016020	membrane	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0472	C
	GO:0016020	membrane	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	C
	GO:0016020	membrane	GO_REF:0000024	ISS: Inferred from Sequence or Structural Similarity	UniProtKB:Q9WU82	C
	GO:0016055	Wnt receptor signaling pathway	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0879	P
	GO:0016055	Wnt receptor signaling pathway	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0016055	Wnt receptor signaling pathway	PMID:10644691^[66]	IDA: Inferred from Direct Assay		P
	GO:0016323	basolateral plasma membrane	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	C
	GO:0016328	lateral plasma membrane	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	C
	GO:0016328	lateral plasma membrane	PMID:12072559^[67]	IDA: Inferred from Direct Assay		C
	GO:0016331	morphogenesis of embryonic epithelium	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0016337	cell-cell adhesion	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0016337	cell-cell adhesion	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000026016	P
	GO:0016337	cell-cell adhesion	PMID:18593713^[68]	IMP: Inferred from Mutant Phenotype		P
	GO:0016342	catenin complex	PMID:18593713^[68]	IDA: Inferred from Direct Assay		C
	GO:0016342	catenin complex	PMID:20302655^[69]	IDA: Inferred from Direct Assay		C
	GO:0016342	catenin complex	PMID:7650039^[70]	IDA: Inferred from Direct Assay		C
	GO:0019899	enzyme binding	PMID:18356165^[71]	IPI: Inferred from Physical Interaction	UniProtKB:Q9UBN7	F
	GO:0019900	kinase binding	PMID:8638126^[72]	IPI: Inferred from Physical Interaction	UniProtKB:P49841	F
	GO:0019901	protein kinase binding	GO_REF:0000033		PANTHER:PTHR23315_AN54	F
	GO:0019903	protein phosphatase binding	PMID:16574648^[73]	IPI: Inferred from Physical Interaction	UniProtKB:Q92729	F
	GO:0019903	protein phosphatase binding	PMID:8663237^[74]	IPI: Inferred from Physical Interaction	UniProtKB:Q15262	F
	GO:0022009	central nervous system vasculogenesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0022009	central nervous system vasculogenesis	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0022405	hair cycle process	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0030018	Z disc	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	C
	GO:0030018	Z disc	GO_REF:0000033		PANTHER:PTHR23315_AN54	C
	GO:0030027	lamellipodium	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	C
	GO:0030027	lamellipodium	GO_REF:0000033		PANTHER:PTHR23315_AN85	C
	GO:0030054	cell junction	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0965	C
	GO:0030054	cell junction	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0038	C
	GO:0030054	cell junction	PMID:17047063^[24]	TAS: Traceable Author Statement		C
	GO:0030054	cell junction	PMID:19038973^[63]	IDA: Inferred from Direct Assay		C
	GO:0030054	cell junction	PMID:20412773^[75]	IDA: Inferred from Direct Assay		C
	GO:0030057	desmosome	GO_REF:0000033		PANTHER:PTHR23315_AN54	C
	GO:0030097	hemopoiesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0030154	cell differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0030217	T cell differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0030316	osteoclast differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0030324	lung development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0030326	embryonic limb morphogenesis	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0030331	estrogen receptor binding	PMID:15304487^[76]	IPI: Inferred from Physical Interaction	UniProtKB:P03372	F
	GO:0030521	androgen receptor signaling pathway	PMID:15572661^[77]	NAS: Non-traceable Author Statement		P
	GO:0030539	male genitalia development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0030539	male genitalia development	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0030856	regulation of epithelial cell differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0030858	positive regulation of epithelial cell differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0030900	forebrain development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0030902	hindbrain development	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0030997	regulation of centriole-centriole cohesion	PMID:18086858^[31]	IDA: Inferred from Direct Assay		P
	GO:0031016	pancreas development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0031016	pancreas development	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0031069	hair follicle morphogenesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0031069	hair follicle morphogenesis	GO_REF:0000033		PANTHER:PTHR23315_AN88	P
	GO:0031253	cell projection membrane	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	C
	GO:0031528	microvillus membrane	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	C
	GO:0031528	microvillus membrane	GO_REF:0000033		PANTHER:PTHR23315_AN85	C
	GO:0031641	regulation of myelination	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0032331	negative regulation of chondrocyte differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0032331	negative regulation of chondrocyte differentiation	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0032355	response to estradiol stimulus	PMID:15304487^[76]	IDA: Inferred from Direct Assay		P
	GO:0032993	protein-DNA complex	PMID:10825188^[10]	IDA: Inferred from Direct Assay		C
	GO:0033077	T cell differentiation in thymus	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0033077	T cell differentiation in thymus	GO_REF:0000033		PANTHER:PTHR23315_AN88	P
	GO:0034097	response to cytokine stimulus	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000026016	P
	GO:0034333	adherens junction assembly	PMID:20086044^[61]	IMP: Inferred from Mutant Phenotype		P
	GO:0034333	adherens junction assembly	PMID:20123964^[3]	IMP: Inferred from Mutant Phenotype		P
	GO:0034394	protein localization at cell surface	PMID:20086044^[61]	IMP: Inferred from Mutant Phenotype		P
	GO:0034613	cellular protein localization	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0034742	APC-Axin-1-beta-catenin complex	PMID:16188939^[78]	IDA: Inferred from Direct Assay		C
	GO:0034747	Axin-APC-beta-catenin-GSK3B complex	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	C
	GO:0034747	Axin-APC-beta-catenin-GSK3B complex	PMID:8638126^[72]	IDA: Inferred from Direct Assay		C
	GO:0035050	embryonic heart tube development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0035112	genitalia morphogenesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0035116	embryonic hindlimb morphogenesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0035117	embryonic arm morphogenesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0035255	ionotropic glutamate receptor binding	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000026016	F
	GO:0035257	nuclear hormone receptor binding	PMID:12799378^[79]	IPI: Inferred from Physical Interaction	UniProtKB:P10275	F
	GO:0035257	nuclear hormone receptor binding	PMID:16344550^[64]	TAS: Traceable Author Statement		F
	GO:0042127	regulation of cell proliferation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0042129	regulation of T cell proliferation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0042129	regulation of T cell proliferation	GO_REF:0000033		PANTHER:PTHR23315_AN88	P
	GO:0042153	RPTP-like protein binding	GO_REF:0000033		PANTHER:PTHR23315_AN54	F
	GO:0042475	odontogenesis of dentine-containing tooth	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0042475	odontogenesis of dentine-containing tooth	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000026016	P
	GO:0042475	odontogenesis of dentine-containing tooth	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0042493	response to drug	PMID:18291362^[80]	IEP: Inferred from Expression Pattern		P
	GO:0042692	muscle cell differentiation	Reactome:REACT_21303	TAS: Traceable Author Statement		P
	GO:0042733	embryonic digit morphogenesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0042981	regulation of apoptosis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0043005	neuron projection	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000026016	C
	GO:0043065	positive regulation of apoptosis	PMID:12970740^[55]	IDA: Inferred from Direct Assay		P
	GO:0043066	negative regulation of apoptosis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0043198	dendritic shaft	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000026016	C
	GO:0043198	dendritic shaft	GO_REF:0000033		PANTHER:PTHR23315_AN85	C
	GO:0043234	protein complex	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000026016	C
	GO:0043296	apical junction complex	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	C
	GO:0043410	positive regulation of MAPKKK cascade	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0043410	positive regulation of MAPKKK cascade	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0043587	tongue morphogenesis	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0043588	skin development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0043627	response to estrogen stimulus	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000026016	P
	GO:0044212	transcription regulatory region DNA binding	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	F
	GO:0044212	transcription regulatory region DNA binding	PMID:18193033^[32]	IDA: Inferred from Direct Assay		F
	GO:0044212	transcription regulatory region DNA binding	PMID:18579517^[81]	IDA: Inferred from Direct Assay		F
	GO:0044325	ion channel binding	PMID:19996314^[58]	IPI: Inferred from Physical Interaction	UniProtKB:Q9UBN4	F
	GO:0044334	canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition	PMID:17072303^[82]	IMP: Inferred from Mutant Phenotype		P
	GO:0044336	canonical Wnt receptor signaling pathway involved in negative regulation of apoptosis	PMID:12154096^[83]	IMP: Inferred from Mutant Phenotype		P
	GO:0045177	apical part of cell	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	C
	GO:0045202	synapse	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000026016	C
	GO:0045202	synapse	GO_REF:0000033		PANTHER:PTHR23315_AN85	C
	GO:0045294	alpha-catenin binding	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	F
	GO:0045294	alpha-catenin binding	PMID:7650039^[70]	IPI: Inferred from Physical Interaction	UniProtKB:P35221	F
	GO:0045294	alpha-catenin binding	PMID:7890674^[42]	IPI: Inferred from Physical Interaction	UniProtKB:P35221	F
	GO:0045296	cadherin binding	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	F
	GO:0045296	cadherin binding	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000026016	F
	GO:0045296	cadherin binding	PMID:12734196^[84]	IPI: Inferred from Physical Interaction	UniProtKB:Q86UP0-1	F
	GO:0045296	cadherin binding	PMID:12734196^[84]	IPI: Inferred from Physical Interaction	UniProtKB:Q86UP0-2	F
	GO:0045296	cadherin binding	PMID:18287330^[33]	IPI: Inferred from Physical Interaction	UniProtKB:P33151	F
	GO:0045296	cadherin binding	PMID:19038973^[63]	IPI: Inferred from Physical Interaction	UniProtKB:P12830	F
	GO:0045445	myoblast differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000026016	P
	GO:0045453	bone resorption	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0045595	regulation of cell differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0045596	negative regulation of cell differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0045603	positive regulation of endothelial cell differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0045667	regulation of osteoblast differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0045669	positive regulation of osteoblast differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0045669	positive regulation of osteoblast differentiation	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0045670	regulation of osteoclast differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0045671	negative regulation of osteoclast differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0045671	negative regulation of osteoclast differentiation	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0045765	regulation of angiogenesis	PMID:18756595^[49]	TAS: Traceable Author Statement		P
	GO:0045768	positive regulation of anti-apoptosis	PMID:18787224^[50]	IMP: Inferred from Mutant Phenotype		P
	GO:0045892	negative regulation of transcription, DNA-dependent	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0045892	negative regulation of transcription, DNA-dependent	PMID:19653274^[85]	IMP: Inferred from Mutant Phenotype		P
	GO:0045893	positive regulation of transcription, DNA-dependent	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0045893	positive regulation of transcription, DNA-dependent	PMID:12949260^[6]	IMP: Inferred from Mutant Phenotype		P
	GO:0045893	positive regulation of transcription, DNA-dependent	PMID:12970740^[55]	IDA: Inferred from Direct Assay		P
	GO:0045893	positive regulation of transcription, DNA-dependent	PMID:18787224^[50]	IDA: Inferred from Direct Assay		P
	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	PMID:11751639^[5]	IDA: Inferred from Direct Assay		P
	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	PMID:14660579^[86]	IDA: Inferred from Direct Assay		P
	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	PMID:15592430^[87]	IMP: Inferred from Mutant Phenotype		P
	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	PMID:19328798^[88]	IMP: Inferred from Mutant Phenotype		P
	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	PMID:9065402^[7]	IDA: Inferred from Direct Assay		P
	GO:0046332	SMAD binding	PMID:18593713^[68]	IPI: Inferred from Physical Interaction	UniProtKB:O15105	F
	GO:0046591	embryonic leg joint morphogenesis	GO_REF:0000024	ISS: Inferred from Sequence or Structural Similarity	UniProtKB:Q02248	P
	GO:0046686	response to cadmium ion	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSRNOP00000026016	P
	GO:0048145	regulation of fibroblast proliferation	PMID:16858403^[22]	TAS: Traceable Author Statement		P
	GO:0048262	determination of dorsal/ventral asymmetry	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0048469	cell maturation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0048471	perinuclear region of cytoplasm	PMID:19038973^[63]	IDA: Inferred from Direct Assay		C
	GO:0048471	perinuclear region of cytoplasm	PMID:19038973^[63]	IDA: Inferred from Direct Assay		C
	GO:0048489	synaptic vesicle transport	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0048489	synaptic vesicle transport	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0048513	organ development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0048538	thymus development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0048538	thymus development	GO_REF:0000033		PANTHER:PTHR23315_AN88	P
	GO:0048599	oocyte development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0048599	oocyte development	GO_REF:0000033		PANTHER:PTHR23315_AN54	P
	GO:0048617	embryonic foregut morphogenesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0048617	embryonic foregut morphogenesis	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0048660	regulation of smooth muscle cell proliferation	PMID:17122440^[89]	IMP: Inferred from Mutant Phenotype		P
	GO:0048715	negative regulation of oligodendrocyte differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0050681	androgen receptor binding	PMID:15572661^[77]	NAS: Non-traceable Author Statement		F
	GO:0050808	synapse organization	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0050808	synapse organization	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0051145	smooth muscle cell differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0051145	smooth muscle cell differentiation	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0051149	positive regulation of muscle cell differentiation	Reactome:REACT_21402	TAS: Traceable Author Statement		P
	GO:0060066	oviduct development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0060070	canonical Wnt receptor signaling pathway	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0060070	canonical Wnt receptor signaling pathway	PMID:12937339^[54]	IDA: Inferred from Direct Assay		P
	GO:0060070	canonical Wnt receptor signaling pathway	PMID:19187541^[52]	IDA: Inferred from Direct Assay		P
	GO:0060173	limb development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0060439	trachea morphogenesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0060440	trachea formation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0060440	trachea formation	GO_REF:0000033		PANTHER:PTHR23315_AN86	P
	GO:0060441	epithelial tube branching involved in lung morphogenesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0060479	lung cell differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0060479	lung cell differentiation	GO_REF:0000033		PANTHER:PTHR23315_AN86	P
	GO:0060484	lung-associated mesenchyme development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0060484	lung-associated mesenchyme development	GO_REF:0000033		PANTHER:PTHR23315_AN86	P
	GO:0060492	lung induction	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0060492	lung induction	GO_REF:0000033		PANTHER:PTHR23315_AN86	P
	GO:0060742	epithelial cell differentiation involved in prostate gland development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0060769	positive regulation of epithelial cell proliferation involved in prostate gland development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0060769	positive regulation of epithelial cell proliferation involved in prostate gland development	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0060789	hair follicle placode formation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0060789	hair follicle placode formation	GO_REF:0000033		PANTHER:PTHR23315_AN88	P
	GO:0060916	mesenchymal cell proliferation involved in lung development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0060916	mesenchymal cell proliferation involved in lung development	GO_REF:0000033		PANTHER:PTHR23315_AN86	P
	GO:0061047	positive regulation of branching involved in lung morphogenesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0061047	positive regulation of branching involved in lung morphogenesis	GO_REF:0000033		PANTHER:PTHR23315_AN86	P
	GO:0061154	endothelial tube morphogenesis	PMID:20123964^[3]	IMP: Inferred from Mutant Phenotype		P
	GO:0061198	fungiform papilla formation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0070369	beta-catenin-TCF7L2 complex	PMID:9065401^[90]	IDA: Inferred from Direct Assay		C
	GO:0070369	beta-catenin-TCF7L2 complex	PMID:9065402^[7]	IDA: Inferred from Direct Assay		C
	GO:0070411	I-SMAD binding	PMID:18593713^[68]	IPI: Inferred from Physical Interaction	UniProtKB:O15105	F
	GO:0070412	R-SMAD binding	PMID:20097766^[91]	IPI: Inferred from Physical Interaction	UniProtKB:P84022	F
	GO:0070602	regulation of centromeric sister chromatid cohesion	PMID:20300119^[56]	IMP: Inferred from Mutant Phenotype		P
	GO:0071363	cellular response to growth factor stimulus	PMID:16858403^[22]	IMP: Inferred from Mutant Phenotype		P
	GO:0071407	cellular response to organic cyclic compound	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0071681	cellular response to indole-3-methanol	PMID:10868478^[92]	IDA: Inferred from Direct Assay		P
	GO:0071944	cell periphery	PMID:19038973^[63]	IDA: Inferred from Direct Assay		C
	GO:0072001	renal system development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0072033	renal vesicle formation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0072033	renal vesicle formation	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0072053	renal inner medulla development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0072053	renal inner medulla development	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0072054	renal outer medulla development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0072054	renal outer medulla development	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0072079	nephron tubule formation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
	GO:0072079	nephron tubule formation	GO_REF:0000033		PANTHER:PTHR23315_AN85	P
	GO:0072182	regulation of nephron tubule epithelial cell differentiation	GO_REF:0000024	ISS: Inferred from Sequence or Structural Similarity	UniProtKB:Q02248	P
	GO:0090279	regulation of calcium ion import	PMID:19996314^[58]	IDA: Inferred from Direct Assay		P
	GO:2000008	regulation of protein localization at cell surface	PMID:19996314^[58]	IDA: Inferred from Direct Assay		P
	GO:2000017	positive regulation of determination of dorsal identity	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000007130	P
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

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[PMID:20307497-0] 1.0 ^1.1 ^1.2 ^1.3 Kim EA et al. (2010) Homeodomain-interacting protein kinase 2 (HIPK2) targets beta-catenin for phosphorylation and proteasomal degradation. Biochem Biophys Res Commun 394: 966-71 PubMed GONUTS page

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HUMAN:CTNB1

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