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HUMAN:CNEP1

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Contents

Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) CTDNEP1 (synonyms: DULLARD)
Protein Name(s) CTD nuclear envelope phosphatase 1

Serine/threonine-protein phosphatase dullard

External Links
UniProt O95476
EMBL AJ011916
AY364239
AC003688
AC120057
CH471108
CH471108
CH471108
BC009295
IPI IPI00383704
RefSeq NP_001137247.1
NP_056158.2
UniGene Hs.513913
HSSP Q9GZU7
ProteinModelPortal O95476
SMR O95476
STRING O95476
PhosphoSite O95476
PRIDE O95476
Ensembl ENST00000318988
ENST00000380825
GeneID 23399
KEGG hsa:23399
UCSC uc002gfd.1
CTD 23399
GeneCards GC17M007147
HGNC HGNC:19085
HPA HPA037439
MIM 610684
neXtProt NX_O95476
PharmGKB PA134937999
eggNOG prNOG18902
GeneTree ENSGT00550000075053
HOGENOM HBG603876
HOVERGEN HBG098153
InParanoid O95476
OMA SRNRLGQ
OrthoDB EOG4J6RRP
PhylomeDB O95476
NextBio 45549
ArrayExpress O95476
Bgee O95476
CleanEx HS_DULLARD
Genevestigator O95476
GO GO:0005789
GO:0016021
GO:0031965
GO:0004722
GO:0006998
GO:0006470
InterPro IPR011948
IPR023214
IPR004274
Gene3D G3DSA:3.40.50.1000
Pfam PF03031
SMART SM00577
SUPFAM SSF56784
TIGRFAMs TIGR02251
PROSITE PS50969

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004721

phosphoprotein phosphatase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:3.1.3.16

F

Seeded From UniProt

GO:0004721

phosphoprotein phosphatase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0904

F

Seeded From UniProt

GO:0004722

protein serine/threonine phosphatase activity

PMID:17420445[1]

IMP: Inferred from Mutant Phenotype

F

Seeded From UniProt

GO:0005634

nucleus

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0539

C

Seeded From UniProt

GO:0005635

nuclear envelope

PMID:17420445[1]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0005737

cytoplasm

PMID:22134922[2]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0005783

endoplasmic reticulum

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0256

C

Seeded From UniProt

GO:0005789

endoplasmic reticulum membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0097

C

Seeded From UniProt

GO:0005789

endoplasmic reticulum membrane

PMID:17420445[1]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0006470

protein dephosphorylation

PMID:17420445[1]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

GO:0006470

protein dephosphorylation

PMID:22134922[2]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

GO:0006998

nuclear envelope organization

PMID:17420445[1]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

GO:0010867

positive regulation of triglyceride biosynthetic process

PMID:22134922[2]

IGI: Inferred from Genetic Interaction

P

Seeded From UniProt

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded From UniProt

GO:0016021

integral to membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded From UniProt

GO:0016311

dephosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011948

P

Seeded From UniProt

GO:0016787

hydrolase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0378

F

Seeded From UniProt

GO:0016791

phosphatase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011948

F

Seeded From UniProt

GO:0031965

nuclear membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0182

C

Seeded From UniProt

GO:0031965

nuclear membrane

PMID:22134922[2]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0034504

protein localization to nucleus

PMID:22134922[2]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

GO:0071595

Nem1-Spo7 phosphatase complex

PMID:22134922[2]

IDA: Inferred from Direct Assay

C

Seeded From UniProt


Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Kim Y et al. (2007) A conserved phosphatase cascade that regulates nuclear membrane biogenesis. Proc Natl Acad Sci U S A 104: 6596-601 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Han S et al. (2012) Nuclear envelope phosphatase 1-regulatory subunit 1 (formerly TMEM188) is the metazoan Spo7p ortholog and functions in the lipin activation pathway. J Biol Chem 287: 3123-37 PubMed GONUTS page
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