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HUMAN:CLC4M
Contents |
| Species (Taxon ID) | Homo sapiens (Human). ([1]) | |
| Gene Name(s) | CLEC4M (synonyms: CD209L, CD209L1, CD299) | |
| Protein Name(s) | C-type lectin domain family 4 member M
CD209 antigen-like protein 1 DC-SIGN-related protein DC-SIGNR Dendritic cell-specific ICAM-3-grabbing non-integrin 2 DC-SIGN2 Liver/lymph node-specific ICAM-3-grabbing non-integrin L-SIGN | |
| External Links | ||
| EMBL | AB015629 AF245219 AF209481 AF209480 AY042234 AY042235 AY042236 AY042237 AY042238 AY042239 AY042240 AF290887 AY343913 AK023750 AK292278 AC008812 BC038851 | |
| IPI | IPI00003402 IPI00156091 IPI00290003 IPI00382671 IPI00385903 IPI00409772 IPI00410004 IPI00410005 IPI00410009 IPI00642143 IPI00874038 | |
| RefSeq | NP_001138377.1 NP_001138378.1 NP_001138379.1 NP_001138380.1 NP_001138381.1 NP_001138382.1 NP_001138383.1 NP_055072.3 | |
| UniGene | Hs.421437 | |
| PDB | 1K9J 1SL6 1XAR 1XPH 1Z0Y 3JQH | |
| PDBsum | 1K9J 1SL6 1XAR 1XPH 1Z0Y 3JQH | |
| ProteinModelPortal | Q9H2X3 | |
| SMR | Q9H2X3 | |
| IntAct | Q9H2X3 | |
| MINT | MINT-1489134 | |
| STRING | Q9H2X3 | |
| PRIDE | Q9H2X3 | |
| Ensembl | ENST00000327325 | |
| GeneID | 10332 | |
| KEGG | hsa:10332 | |
| UCSC | uc002mhy.1 uc002mhz.1 uc002mia.1 uc002mib.1 uc002mic.1 uc002mie.1 uc002mig.1 uc002mih.1 | |
| CTD | 10332 | |
| GeneCards | GC19P007498 | |
| HGNC | HGNC:13523 | |
| MIM | 605872 | |
| neXtProt | NX_Q9H2X3 | |
| eggNOG | prNOG19369 | |
| GeneTree | ENSGT00580000081277 | |
| HOVERGEN | HBG050992 | |
| InParanoid | Q9H2X3 | |
| OMA | NRFSWMG | |
| OrthoDB | EOG40K7ZZ | |
| PhylomeDB | Q9H2X3 | |
| NextBio | 39173 | |
| ArrayExpress | Q9H2X3 | |
| Bgee | Q9H2X3 | |
| Genevestigator | Q9H2X3 | |
| GermOnline | ENSG00000104938 | |
| GO | GO:0005737 GO:0005576 GO:0005887 GO:0030369 GO:0005537 GO:0046872 GO:0042605 GO:0046790 GO:0009988 GO:0006897 GO:0045087 GO:0035556 GO:0046795 GO:0007159 GO:0046968 GO:0019079 GO:0019062 | |
| InterPro | IPR002353 IPR001304 IPR016186 IPR018378 IPR016187 | |
| Gene3D | G3DSA:3.10.100.10 | |
| Pfam | PF00059 | |
| PRINTS | PR00356 | |
| SMART | SM00034 | |
| SUPFAM | SSF56436 | |
| PROSITE | PS00615 PS50041 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004872 |
receptor activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004872 |
receptor activity |
NAS: Non-traceable Author Statement |
|
F |
Seeded From UniProt |
|||
| GO:0005488 |
binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005488 |
binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005488 |
binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005488 |
binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005529 |
sugar binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005529 |
sugar binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005529 |
sugar binding |
NAS: Non-traceable Author Statement |
|
F |
Seeded From UniProt |
|||
| GO:0005537 |
mannose binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005576 |
extracellular region |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005576 |
extracellular region |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0243 |
C |
Seeded From UniProt |
|||
| GO:0005622 |
intracellular |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
|||
| GO:0005737 |
cytoplasm |
NAS: Non-traceable Author Statement |
|
C |
Seeded From UniProt |
|||
| GO:0005886 |
plasma membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005886 |
plasma membrane |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0039 |
C |
Seeded From UniProt |
|||
| GO:0005887 |
integral to plasma membrane |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
|||
| GO:0006897 |
endocytosis |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007159 |
leukocyte cell-cell adhesion |
NAS: Non-traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0009988 |
cell-cell recognition |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016020 |
membrane |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
|||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0019048 |
virus-host interaction |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0019062 |
virion attachment to host cell surface receptor |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0019079 |
viral genome replication |
NAS: Non-traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0019882 |
antigen processing and presentation |
NAS: Non-traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0030369 |
ICAM-3 receptor activity |
NAS: Non-traceable Author Statement |
|
F |
Seeded From UniProt |
|||
| GO:0035556 |
intracellular signal transduction |
NAS: Non-traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0042605 |
peptide antigen binding |
NAS: Non-traceable Author Statement |
|
F |
Seeded From UniProt |
|||
| GO:0044419 |
interspecies interaction between organisms |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0045087 |
innate immune response |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0046790 |
virion binding |
TAS: Traceable Author Statement |
|
F |
Seeded From UniProt |
|||
| GO:0046795 |
intracellular virion transport |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0046872 |
metal ion binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0046968 |
peptide antigen transport |
NAS: Non-traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0001618 |
viral receptor activity |
IMP: Inferred from Mutant Phenotype |
F |
Fig. 2A |
complete | |||
| GO:0001618 |
viral receptor activity |
IDA: Inferred from Direct Assay |
F |
Fig. 4 |
complete | |||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Bashirova AA et al. (2001) A dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN)-related protein is highly expressed on human liver sinusoidal endothelial cells and promotes HIV-1 infection. J Exp Med 193: 671-8 PubMed GONUTS page
- ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 Mummidi S et al. (2001) Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts. J Biol Chem 276: 33196-212 PubMed GONUTS page
- ↑ Yokoyama-Kobayashi M et al. (1999) Selection of cDNAs encoding putative type II membrane proteins on the cell surface from a human full-length cDNA bank. Gene 228: 161-7 PubMed GONUTS page
- ↑ 4.0 4.1 Jeffers SA et al. (2004) CD209L (L-SIGN) is a receptor for severe acute respiratory syndrome coronavirus. Proc Natl Acad Sci U S A 101: 15748-53 PubMed GONUTS page
