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HUMAN:CH3L1
Contents |
| Species (Taxon ID) | Homo sapiens (Human). ([1]) | |
| Gene Name(s) | CHI3L1 | |
| Protein Name(s) | Chitinase-3-like protein 1
39 kDa synovial protein Cartilage glycoprotein 39 CGP-39 GP-39 hCGP-39 YKL-40 | |
| External Links | ||
| EMBL | M80927 Y08374 Y08375 Y08376 Y08377 Y08378 BT007223 AK312911 CH471067 BC008568 BC038354 BC039132 | |
| IPI | IPI00002147 | |
| PIR | A49562 | |
| RefSeq | NP_001267.2 | |
| UniGene | Hs.382202 | |
| PDB | 1HJV 1HJW 1HJX 1LA7 1NWR 1NWS 1NWT 1NWU | |
| PDBsum | 1HJV 1HJW 1HJX 1LA7 1NWR 1NWS 1NWT 1NWU | |
| ProteinModelPortal | P36222 | |
| SMR | P36222 | |
| STRING | P36222 | |
| CAZy | GH18 | |
| PhosphoSite | P36222 | |
| PeptideAtlas | P36222 | |
| PRIDE | P36222 | |
| Ensembl | ENST00000255409 | |
| GeneID | 1116 | |
| KEGG | hsa:1116 | |
| UCSC | uc001gzi.2 | |
| CTD | 1116 | |
| GeneCards | GC01M174313 | |
| H-InvDB | HIX0001487 | |
| HGNC | HGNC:1932 | |
| MIM | 601525 611960 | |
| neXtProt | NX_P36222 | |
| PharmGKB | PA26463 | |
| eggNOG | prNOG13745 | |
| HOGENOM | HBG443716 | |
| HOVERGEN | HBG011684 | |
| InParanoid | P36222 | |
| OMA | TQSRRTF | |
| OrthoDB | EOG40K7ZX | |
| PhylomeDB | P36222 | |
| NextBio | 4626 | |
| ArrayExpress | P36222 | |
| Bgee | P36222 | |
| CleanEx | HS_CHI3L1 | |
| Genevestigator | P36222 | |
| GermOnline | ENSG00000133048 | |
| GO | GO:0005615 GO:0005578 GO:0043169 GO:0004568 GO:0005201 GO:0005529 GO:0006032 | |
| InterPro | IPR011583 IPR001223 IPR013781 IPR017853 | |
| Gene3D | G3DSA:3.20.20.80 | |
| Pfam | PF00704 | |
| SMART | SM00636 | |
| SUPFAM | SSF51445 | |
| PROSITE | PS01095 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003824 |
catalytic activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004553 |
hydrolase activity, hydrolyzing O-glycosyl compounds |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004568 |
chitinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005201 |
extracellular matrix structural constituent |
TAS: Traceable Author Statement |
|
F |
Seeded From UniProt |
|||
| GO:0005529 |
sugar binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005576 |
extracellular region |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005578 |
proteinaceous extracellular matrix |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
|||
| GO:0005615 |
extracellular space |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000057440 |
C |
Seeded From UniProt |
|||
| GO:0005615 |
extracellular space |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0112 |
C |
Seeded From UniProt |
|||
| GO:0005615 |
extracellular space |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
|||
| GO:0005975 |
carbohydrate metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0005975 |
carbohydrate metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006032 |
chitin catabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0043169 |
cation binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0071347 |
cellular response to interleukin-1 |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000057440 |
P |
Seeded From UniProt |
|||
| GO:0071356 |
cellular response to tumor necrosis factor |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000057440 |
P |
Seeded From UniProt |
|||
| GO:0003674 |
molecular function |
IDA: Inferred from Direct Assay |
F |
Figure 2: The ratio of invading cells decreased significantly in both Res- and siRNA-pretreated U87 cells. |
complete | |||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Hakala BE et al. (1993) Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family. J Biol Chem 268: 25803-10 PubMed GONUTS page
- ↑ Zhang W et al. (2010) Resveratrol represses YKL-40 expression in human glioma U87 cells. BMC Cancer 10: 593 PubMed GONUTS page
c |
c cont.e |
hmps |
