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HUMAN:CDC5L

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Contents

Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) CDC5L (synonyms: KIAA0432, PCDC5RP)
Protein Name(s) Cell division cycle 5-like protein

Cdc5-like protein Pombe cdc5-related protein

External Links
UniProt Q99459
EMBL U86753
AB007892
AY518540
AL133262
AL353588
AL353588
AL133262
BC001568
D85423
IPI IPI00465294
RefSeq NP_001244.1
UniGene Hs.485471
PDB 2DIM
2DIN
PDBsum 2DIM
2DIN
ProteinModelPortal Q99459
SMR Q99459
IntAct Q99459
MINT MINT-133723
STRING Q99459
PhosphoSite Q99459
DMDM 73619933
PeptideAtlas Q99459
PRIDE Q99459
Ensembl ENST00000371477
GeneID 988
KEGG hsa:988
UCSC uc003oxl.1
CTD 988
GeneCards GC06P044402
H-InvDB HIX0005928
HGNC HGNC:1743
HPA CAB012275
HPA006302
HPA011361
MIM 602868
neXtProt NX_Q99459
PharmGKB PA26270
eggNOG prNOG18711
GeneTree ENSGT00550000074922
HOGENOM HBG630413
HOVERGEN HBG052766
InParanoid Q99459
OMA PRNDYEI
OrthoDB EOG48GW2S
PhylomeDB Q99459
NextBio 4146
PMAP-CutDB Q99459
ArrayExpress Q99459
Bgee Q99459
CleanEx HS_CDC5L
Genevestigator Q99459
GermOnline ENSG00000096401
GO GO:0071013
GO:0005737
GO:0016607
GO:0005730
GO:0003677
GO:0003723
GO:0007049
GO:0000398
GO:0006355
GO:0006351
InterPro IPR021786
IPR009057
IPR012287
IPR014778
IPR015495
IPR001005
IPR017930
Gene3D G3DSA:1.10.10.60
KO K12860
PANTHER PTHR10641
Pfam PF11831
PF00249
SMART SM00717
SUPFAM SSF46689
PROSITE PS51294

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000398

nuclear mRNA splicing, via spliceosome

PMID:11991638[1]

IC: Inferred by Curator

GO:0071013

P

Seeded From UniProt

GO:0003677

DNA binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001005

F

Seeded From UniProt

GO:0003677

DNA binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012287

F

Seeded From UniProt

GO:0003677

DNA binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0238

F

Seeded From UniProt

GO:0003677

DNA binding

PMID:8917598[2]

NAS: Non-traceable Author Statement

F

Seeded From UniProt

GO:0003723

RNA binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0694

F

Seeded From UniProt

GO:0005515

protein binding

PMID:18722174[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q8WYA6

F

Seeded From UniProt

GO:0005634

nucleus

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0539

C

Seeded From UniProt

GO:0005634

nucleus

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000027264

C

Seeded From UniProt

GO:0005634

nucleus

GO_REF:0000029

NAS: Non-traceable Author Statement

C

Seeded From UniProt

GO:0005634

nucleus

PMID:18029348[4]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0005681

spliceosomal complex

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0747

C

Seeded From UniProt

GO:0005730

nucleolus

PMID:18029348[4]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0005737

cytoplasm

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded From UniProt

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

Seeded From UniProt

GO:0006351

transcription, DNA-dependent

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0804

P

Seeded From UniProt

GO:0006355

regulation of transcription, DNA-dependent

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012287

P

Seeded From UniProt

GO:0006355

regulation of transcription, DNA-dependent

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0805

P

Seeded From UniProt

GO:0006355

regulation of transcription, DNA-dependent

GO_REF:0000029

NAS: Non-traceable Author Statement

P

Seeded From UniProt

GO:0006397

mRNA processing

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0507

P

Seeded From UniProt

GO:0007049

cell cycle

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0131

P

Seeded From UniProt

GO:0008380

RNA splicing

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0508

P

Seeded From UniProt

GO:0016607

nuclear speck

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000027264

C

Seeded From UniProt

GO:0016607

nuclear speck

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0186

C

Seeded From UniProt

GO:0016607

nuclear speck

PMID:16332694[5]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0019904

protein domain specific binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSRNOP00000027264

F

Seeded From UniProt

GO:0071013

catalytic step 2 spliceosome

PMID:11991638[1]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0005730

nucleolus

PMID:18029348[4]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0005737

cytoplasm

PMID:9038199[6]

IDA: Inferred from Direct Assay

C

Figure 4a found that PCDC5RP was exclusively in the cytoplasm in transfected CV-1 cells.

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Jurica MS et al. (2002) Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. RNA 8: 426-39 PubMed GONUTS page
  2. Hirayama T & Shinozaki K (1996) A cdc5+ homolog of a higher plant, Arabidopsis thaliana. Proc Natl Acad Sci U S A 93: 13371-6 PubMed GONUTS page
  3. Conticello SG et al. (2008) Interaction between antibody-diversification enzyme AID and spliceosome-associated factor CTNNBL1. Mol Cell 31: 474-84 PubMed GONUTS page
  4. 4.0 4.1 4.2 Barbe L et al. (2008) Toward a confocal subcellular atlas of the human proteome. Mol Cell Proteomics 7: 499-508 PubMed GONUTS page
  5. Grillari J et al. (2005) SNEV is an evolutionarily conserved splicing factor whose oligomerization is necessary for spliceosome assembly. Nucleic Acids Res 33: 6868-83 PubMed GONUTS page
  6. Bernstein HS & Coughlin SR (1997) Pombe Cdc5-related protein. A putative human transcription factor implicated in mitogen-activated signaling. J Biol Chem 272: 5833-7 PubMed GONUTS page
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