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HUMAN:CD63

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Contents

Species (Taxon ID) Homo sapiens (Human). ([1])
Gene Name(s) CD63 (synonyms: MLA1, TSPAN30)
Protein Name(s) CD63 antigen

Granulophysin Lysosomal-associated membrane protein 3 LAMP-3 Melanoma-associated antigen ME491 OMA81H Ocular melanoma-associated antigen Tetraspanin-30 Tspan-30

External Links
EMBL X07982
M59907
M58485
S93788
X62654
AK311893
CR542096
BT007073
BT020137
BT020138
CH471054
BC002349
BC013017
IPI IPI00215998
PIR I38016
RefSeq NP_001771.1
UniGene Hs.445570
ProteinModelPortal P08962
IntAct P08962
MINT MINT-2981823
STRING P08962
PRIDE P08962
Ensembl ENST00000257857
GeneID 967
KEGG hsa:967
UCSC uc001shm.1
CTD 967
GeneCards GC12M053159
H-InvDB HIX0010704
HGNC HGNC:1692
HPA CAB026356
HPA010088
MIM 155740
neXtProt NX_P08962
eggNOG prNOG15980
HOGENOM HBG716506
HOVERGEN HBG107306
InParanoid P08962
OMA EFNKDFR
OrthoDB EOG4HX51Z
PhylomeDB P08962
Reactome REACT_604
NextBio 4044
ArrayExpress P08962
Bgee P08962
CleanEx HS_CD63
Genevestigator P08962
GermOnline ENSG00000135404
GO GO:0005887
GO:0031902
GO:0005765
GO:0031088
GO:0030168
GO:0002576
InterPro IPR018499
IPR018503
IPR008952
IPR000301
KO K06497
Pfam PF00335
PRINTS PR00259
SUPFAM SSF48652
PROSITE PS00421

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0002576

platelet degranulation

Reactome:REACT_318

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0005764

lysosome

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0458

C

Seeded From UniProt

GO:0005765

lysosomal membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0157

C

Seeded From UniProt

GO:0005765

lysosomal membrane

PMID:1993697[1]

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005768

endosome

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0967

C

Seeded From UniProt

GO:0005886

plasma membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded From UniProt

GO:0005886

plasma membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0039

C

Seeded From UniProt

GO:0005886

plasma membrane

PMID:8661157[2]

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005886

plasma membrane

PMID:9602068[3]

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005886

plasma membrane

Reactome:REACT_21266

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0005887

integral to plasma membrane

PMID:1993697[1]

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0007596

blood coagulation

Reactome:REACT_604

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0010008

endosome membrane

PMID:15229288[4]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded From UniProt

GO:0016021

integral to membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000301

C

Seeded From UniProt

GO:0016021

integral to membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008952

C

Seeded From UniProt

GO:0016021

integral to membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR018499

C

Seeded From UniProt

GO:0016021

integral to membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR018503

C

Seeded From UniProt

GO:0016021

integral to membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded From UniProt

GO:0030168

platelet activation

Reactome:REACT_798

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0031088

platelet dense granule membrane

Reactome:REACT_21266

TAS: Traceable Author Statement

C

Seeded From UniProt

GO:0031902

late endosome membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0151

C

Seeded From UniProt

GO:0005771

multivesicular body

PMID:22072966[5]

IMP: Inferred from Mutant Phenotype

C

Fig. 7B

complete

GO:0030139

endocytic vesicle

PMID:22072966[5]

IMP: Inferred from Mutant Phenotype

C

Fig. 6B and Fig. 7B

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Metzelaar MJ et al. (1991) CD63 antigen. A novel lysosomal membrane glycoprotein, cloned by a screening procedure for intracellular antigens in eukaryotic cells. J Biol Chem 266: 3239-45 PubMed GONUTS page
  2. Gwynn B et al. (1996) Genetic localization of Cd63, a member of the transmembrane 4 superfamily, reveals two distinct loci in the mouse genome. Genomics 35: 389-91 PubMed GONUTS page
  3. Fitter S et al. (1998) Characterisation of the mouse homologue of CD151 (PETA-3/SFA-1); genomic structure, chromosomal localisation and identification of 2 novel splice forms. Biochim Biophys Acta 1398: 75-85 PubMed GONUTS page
  4. Coumailleau F et al. (2004) Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment. Mol Biol Cell 15: 4444-56 PubMed GONUTS page
  5. 5.0 5.1 Caillet M et al. (2011) Rab7A is required for efficient production of infectious HIV-1. PLoS Pathog 7: e1002347 PubMed GONUTS page
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