HUMAN:B7ZLG1

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Species (Taxon ID)	Homo sapiens (Human). ([1])
Gene Name(s)	FOXP3
Protein Name(s)	FOXP3 protein
External Links
EMBL	BC143786
IPI	IPI00922760
UniGene	Hs.247700
STRING	B7ZLG1
HOVERGEN	HBG051656
Bgee	B7ZLG1
GO	GO:0008270
InterPro	IPR001766 IPR018122 IPR011991 IPR007087 IPR015880 IPR013087
Gene3D	G3DSA:1.10.10.10 G3DSA:3.30.160.60
Pfam	PF00250
PRINTS	PR00053
SMART	SM00339 SM00355
PROSITE	PS00658 PS50039 PS00028

Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes	Status
	GO:0000122	negative regulation of transcription from RNA polymerase II promoter	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0001782	B cell homeostasis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0001816	cytokine production	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0002262	myeloid cell homeostasis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0002456	T cell mediated immunity	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0002507	tolerance induction	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0002513	tolerance induction to self antigen	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0002637	regulation of immunoglobulin production	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0002666	positive regulation of T cell tolerance induction	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0002669	positive regulation of T cell anergy	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0002677	negative regulation of chronic inflammatory response	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0002851	positive regulation of peripheral T cell tolerance induction	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0003676	nucleic acid binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013087	F	Seeded From UniProt
	GO:0003677	DNA binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0238	F	Seeded From UniProt
	GO:0003700	sequence-specific DNA binding transcription factor activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001766	F	Seeded From UniProt
	GO:0003700	sequence-specific DNA binding transcription factor activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR018122	F	Seeded From UniProt
	GO:0003700	sequence-specific DNA binding transcription factor activity	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	F	Seeded From UniProt
	GO:0003705	sequence-specific distal enhancer binding RNA polymerase II transcription factor activity	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	F	Seeded From UniProt
	GO:0003714	transcription corepressor activity	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	F	Seeded From UniProt
	GO:0005622	intracellular	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007087	C	Seeded From UniProt
	GO:0005622	intracellular	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR015880	C	Seeded From UniProt
	GO:0005622	intracellular	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	C	Seeded From UniProt
	GO:0005634	nucleus	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	C	Seeded From UniProt
	GO:0005737	cytoplasm	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	C	Seeded From UniProt
	GO:0006351	transcription, DNA-dependent	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0006355	regulation of transcription, DNA-dependent	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001766	P	Seeded From UniProt
	GO:0006355	regulation of transcription, DNA-dependent	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR018122	P	Seeded From UniProt
	GO:0008270	zinc ion binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007087	F	Seeded From UniProt
	GO:0008270	zinc ion binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR015880	F	Seeded From UniProt
	GO:0032689	negative regulation of interferon-gamma production	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0032693	negative regulation of interleukin-10 production	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0032703	negative regulation of interleukin-2 production	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0032713	negative regulation of interleukin-4 production	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0032714	negative regulation of interleukin-5 production	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0032715	negative regulation of interleukin-6 production	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0032720	negative regulation of tumor necrosis factor production	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0032831	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0032914	positive regulation of transforming growth factor beta1 production	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0033092	positive regulation of immature T cell proliferation in thymus	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0035066	positive regulation of histone acetylation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0035067	negative regulation of histone acetylation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0042130	negative regulation of T cell proliferation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0042803	protein homodimerization activity	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	F	Seeded From UniProt
	GO:0043565	sequence-specific DNA binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001766	F	Seeded From UniProt
	GO:0043565	sequence-specific DNA binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR018122	F	Seeded From UniProt
	GO:0043565	sequence-specific DNA binding	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	F	Seeded From UniProt
	GO:0045066	regulatory T cell differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0045077	negative regulation of interferon-gamma biosynthetic process	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0045085	negative regulation of interleukin-2 biosynthetic process	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0045591	positive regulation of regulatory T cell differentiation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0045892	negative regulation of transcription, DNA-dependent	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0045893	positive regulation of transcription, DNA-dependent	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0048294	negative regulation of isotype switching to IgE isotypes	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0048302	regulation of isotype switching to IgG isotypes	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0050672	negative regulation of lymphocyte proliferation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0050728	negative regulation of inflammatory response	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0050852	T cell receptor signaling pathway	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000111405	P	Seeded From UniProt
	GO:0001819	positive regulation of cytokine production	PMID:22079196^[1]	IMP: Inferred from Mutant Phenotype		P	Fig. 5	complete
	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	PMID:22079196^[1]	IMP: Inferred from Mutant Phenotype		P	Fig. 2	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Sun L et al. (2012) Foxp3 is critical for human natural CD4+CD25+ regulatory T cells to suppress alloimmune response. Transpl Immunol 26: 71-80 PubMed GONUTS page

[PMID:22079196-0] 1.0 ^1.1 Sun L et al. (2012) Foxp3 is critical for human natural CD4+CD25+ regulatory T cells to suppress alloimmune response. Transpl Immunol 26: 71-80 PubMed GONUTS page

[1]

HUMAN:B7ZLG1

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