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HUMAN:ATX7
Contents |
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | ATXN7 (synonyms: SCA7) | |
| Protein Name(s) | Ataxin-7
Spinocerebellar ataxia type 7 protein | |
| External Links | ||
| UniProt | O15265 | |
| EMBL | AJ000517 AF032102 AF032103 AF032105 AA398030 | |
| IPI | IPI00005743 IPI00332082 | |
| PIR | T09193 | |
| RefSeq | NP_000324.1 NP_001170858.1 | |
| UniGene | Hs.729041 | |
| PDB | 2KKR | |
| PDBsum | 2KKR | |
| ProteinModelPortal | O15265 | |
| SMR | O15265 | |
| IntAct | O15265 | |
| MINT | MINT-2862470 | |
| STRING | O15265 | |
| PhosphoSite | O15265 | |
| PRIDE | O15265 | |
| Ensembl | ENST00000295900 ENST00000487717 | |
| GeneID | 6314 | |
| KEGG | hsa:6314 | |
| UCSC | uc003dlv.2 uc010hnv.1 | |
| CTD | 6314 | |
| GeneCards | GC03P063825 | |
| H-InvDB | HIX0030703 | |
| HGNC | HGNC:10560 | |
| HPA | HPA034989 | |
| MIM | 164500 607640 | |
| neXtProt | NX_O15265 | |
| Orphanet | 94147 | |
| eggNOG | prNOG19056 | |
| HOVERGEN | HBG004320 | |
| OMA | GAMDPVC | |
| OrthoDB | EOG4DV5KV | |
| NextBio | 24505 | |
| PMAP-CutDB | O15265 | |
| ArrayExpress | O15265 | |
| Bgee | O15265 | |
| CleanEx | HS_ATXN7 | |
| Genevestigator | O15265 | |
| GermOnline | ENSG00000163635 | |
| GO | GO:0005737 GO:0016363 GO:0005730 GO:0005515 GO:0008270 GO:0008219 GO:0016578 GO:0006997 GO:0006355 GO:0006351 GO:0007601 | |
| InterPro | IPR013243 IPR015880 | |
| KO | K11318 | |
| Pfam | PF08313 | |
| SMART | SM00355 | |
| PROSITE | PS51505 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded From UniProt |
||||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded From UniProt |
||||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded From UniProt |
||||
| GO:0005622 |
intracellular |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0191 |
C |
Seeded From UniProt |
|||
| GO:0005634 |
nucleus |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
|||
| GO:0005634 |
nucleus |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0005730 |
nucleolus |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0188 |
C |
Seeded From UniProt |
|||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0086 |
C |
Seeded From UniProt |
|||
| GO:0005737 |
cytoplasm |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0006351 |
transcription, DNA-dependent |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006355 |
regulation of transcription, DNA-dependent |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006997 |
nucleus organization |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0007601 |
visual perception |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0008219 |
cell death |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0008270 |
zinc ion binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0016363 |
nuclear matrix |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0181 |
C |
Seeded From UniProt |
|||
| GO:0016578 |
histone deubiquitination |
IDA: Inferred from Direct Assay |
|
P |
Seeded From UniProt |
|||
| GO:0005730 |
nucleolus |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Lebre AS et al. (2001) Ataxin-7 interacts with a Cbl-associated protein that it recruits into neuronal intranuclear inclusions. Hum Mol Genet 10: 1201-13 PubMed GONUTS page
- ↑ 2.0 2.1 Helmlinger D et al. (2004) Ataxin-7 is a subunit of GCN5 histone acetyltransferase-containing complexes. Hum Mol Genet 13: 1257-65 PubMed GONUTS page
- ↑ 3.0 3.1 Kaytor MD et al. (1999) Nuclear localization of the spinocerebellar ataxia type 7 protein, ataxin-7. Hum Mol Genet 8: 1657-64 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Barbe L et al. (2008) Toward a confocal subcellular atlas of the human proteome. Mol Cell Proteomics 7: 499-508 PubMed GONUTS page
- ↑ David G et al. (1997) Cloning of the SCA7 gene reveals a highly unstable CAG repeat expansion. Nat Genet 17: 65-70 PubMed GONUTS page
- ↑ Zhao Y et al. (2008) A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing. Mol Cell 29: 92-101 PubMed GONUTS page
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