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HUMAN:APBB2
Contents |
| Species (Taxon ID) | Homo sapiens (Human). ([1]) | |
| Gene Name(s) | APBB2 (synonyms: FE65L, FE65L1) | |
| Protein Name(s) | Amyloid beta A4 precursor protein-binding family B member 2
Protein Fe65-like 1 | |
| External Links | ||
| EMBL | AC093804 AC096712 AC108937 AC131953 BC027946 U62325 | |
| IPI | IPI00470455 IPI00470456 | |
| RefSeq | NP_001159522.1 NP_775098.2 | |
| UniGene | Hs.479602 | |
| ProteinModelPortal | Q92870 | |
| SMR | Q92870 | |
| IntAct | Q92870 | |
| MINT | MINT-1493142 | |
| STRING | Q92870 | |
| PhosphoSite | Q92870 | |
| PRIDE | Q92870 | |
| Ensembl | ENST00000316212 | |
| GeneID | 323 | |
| KEGG | hsa:323 | |
| UCSC | uc003gvl.1 uc003gvm.1 | |
| CTD | 323 | |
| GeneCards | GC04M040134 | |
| H-InvDB | HIX0020340 | |
| HGNC | HGNC:582 | |
| HPA | HPA023542 | |
| MIM | 602710 | |
| neXtProt | NX_Q92870 | |
| GeneTree | ENSGT00390000000002 | |
| HOGENOM | HBG443527 | |
| HOVERGEN | HBG050524 | |
| InParanoid | Q92870 | |
| NextBio | 1325 | |
| ArrayExpress | Q92870 | |
| Bgee | Q92870 | |
| CleanEx | HS_APBB2 | |
| Genevestigator | Q92870 | |
| GermOnline | ENSG00000163697 | |
| GO | GO:0030426 GO:0030027 GO:0016020 GO:0005634 GO:0045202 GO:0001540 GO:0008134 GO:0007050 GO:0035556 GO:0030308 GO:0045749 GO:0006355 | |
| InterPro | IPR011993 IPR006020 IPR001202 | |
| Gene3D | G3DSA:2.20.70.10 G3DSA:2.30.29.30 | |
| KO | K04530 | |
| Pfam | PF00640 PF00397 | |
| SMART | SM00462 SM00456 | |
| SUPFAM | SSF51045 | |
| PROSITE | PS01179 PS01159 PS50020 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001540 |
beta-amyloid binding |
ISS: Inferred from Sequence or Structural Similarity |
F |
Seeded From UniProt |
||||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded From UniProt |
||||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded From UniProt |
||||
| GO:0005622 |
intracellular |
NAS: Non-traceable Author Statement |
|
C |
Seeded From UniProt |
|||
| GO:0005634 |
nucleus |
ISS: Inferred from Sequence or Structural Similarity |
C |
Seeded From UniProt |
||||
| GO:0006355 |
regulation of transcription, DNA-dependent |
ISS: Inferred from Sequence or Structural Similarity |
P |
Seeded From UniProt |
||||
| GO:0007050 |
cell cycle arrest |
ISS: Inferred from Sequence or Structural Similarity |
P |
Seeded From UniProt |
||||
| GO:0008134 |
transcription factor binding |
ISS: Inferred from Sequence or Structural Similarity |
F |
Seeded From UniProt |
||||
| GO:0016020 |
membrane |
NAS: Non-traceable Author Statement |
|
C |
Seeded From UniProt |
|||
| GO:0030027 |
lamellipodium |
ISS: Inferred from Sequence or Structural Similarity |
C |
Seeded From UniProt |
||||
| GO:0030308 |
negative regulation of cell growth |
ISS: Inferred from Sequence or Structural Similarity |
P |
Seeded From UniProt |
||||
| GO:0030426 |
growth cone |
ISS: Inferred from Sequence or Structural Similarity |
C |
Seeded From UniProt |
||||
| GO:0035556 |
intracellular signal transduction |
NAS: Non-traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0045202 |
synapse |
ISS: Inferred from Sequence or Structural Similarity |
C |
Seeded From UniProt |
||||
| GO:0045749 |
negative regulation of S phase of mitotic cell cycle |
ISS: Inferred from Sequence or Structural Similarity |
P |
Seeded From UniProt |
||||
| GO:0031175 |
neuron projection development |
IDA: Inferred from Direct Assay |
P |
sAPP-Beta induces axon elongation. Fig.2 |
complete | |||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Guénette SY et al. (1996) Association of a novel human FE65-like protein with the cytoplasmic domain of the beta-amyloid precursor protein. Proc Natl Acad Sci U S A 93: 10832-7 PubMed GONUTS page
- ↑ Chasseigneaux S et al. (2011) Secreted amyloid precursor protein β and secreted amyloid precursor protein α induce axon outgrowth in vitro through Egr1 signaling pathway. PLoS One 6: e16301 PubMed GONUTS page
bcgi |
lmn |
n cont.prst |
