GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
HUMAN:AOFA
Contents |
| Species (Taxon ID) | Homo sapiens (Human). ([1]) | |
| Gene Name(s) | MAOA | |
| Protein Name(s) | Amine oxidase [flavin-containing] A
Monoamine oxidase type A MAO-A | |
| External Links | ||
| EMBL | M69226 M68840 X60806 X60807 X60808 X60809 X60810 X60811 X60812 X60813 X60814 X60815 X60816 X60817 X60818 X60819 M68857 M68843 M68844 M68845 M68846 M68847 M68848 M68849 M68850 M68851 M68852 M68853 M68854 M68855 M68856 BC008064 M89636 S81371 S72704 | |
| IPI | IPI00008483 | |
| PIR | A36175 | |
| RefSeq | NP_000231.1 | |
| UniGene | Hs.183109 | |
| PDB | 1H8Q 2BXR 2BXS 2Z5X 2Z5Y | |
| PDBsum | 1H8Q 2BXR 2BXS 2Z5X 2Z5Y | |
| ProteinModelPortal | P21397 | |
| SMR | P21397 | |
| IntAct | P21397 | |
| MINT | MINT-4054607 | |
| STRING | P21397 | |
| PhosphoSite | P21397 | |
| PeptideAtlas | P21397 | |
| PRIDE | P21397 | |
| Ensembl | ENST00000338702 | |
| GeneID | 4128 | |
| KEGG | hsa:4128 | |
| UCSC | uc004dfy.1 | |
| CTD | 4128 | |
| GeneCards | GC0XP041246 | |
| H-InvDB | HIX0021483 | |
| HGNC | HGNC:6833 | |
| HPA | CAB009437 | |
| MIM | 300615 309850 | |
| neXtProt | NX_P21397 | |
| Orphanet | 3057 | |
| PharmGKB | PA236 | |
| eggNOG | prNOG13631 | |
| HOGENOM | HBG556224 | |
| HOVERGEN | HBG004255 | |
| InParanoid | P21397 | |
| OMA | YKEAFWK | |
| OrthoDB | EOG412M55 | |
| PhylomeDB | P21397 | |
| BioCyc | MetaCyc:ENSG00000094598-MONOMER | |
| BRENDA | 1.4.3.4 | |
| Reactome | REACT_111217 REACT_13685 | |
| DrugBank | DB00918 DB00190 DB01068 DB00988 DB00176 DB01381 DB00458 DB01247 DB01235 DB00601 DB00186 DB01171 DB00184 DB00368 DB00780 DB00830 DB00191 DB00388 DB00397 DB00852 DB01367 DB00140 DB00953 DB01037 DB00669 DB00624 DB00752 DB00315 | |
| NextBio | 16206 | |
| ArrayExpress | P21397 | |
| Bgee | P21397 | |
| CleanEx | HS_MAOA | |
| Genevestigator | P21397 | |
| GermOnline | ENSG00000189221 | |
| GO | GO:0016021 GO:0005741 GO:0008131 GO:0007610 GO:0042136 GO:0042135 GO:0007269 GO:0006805 | |
| InterPro | IPR002937 IPR001613 | |
| KO | K00274 | |
| Pfam | PF01593 | |
| PRINTS | PR00757 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005625 |
soluble fraction |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000003910 |
C |
Seeded From UniProt |
|||
| GO:0005739 |
mitochondrion |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005741 |
mitochondrial outer membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005741 |
mitochondrial outer membrane |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000003910 |
C |
Seeded From UniProt |
|||
| GO:0005741 |
mitochondrial outer membrane |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0172 |
C |
Seeded From UniProt |
|||
| GO:0005741 |
mitochondrial outer membrane |
Reactome:REACT_15390 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0005741 |
mitochondrial outer membrane |
Reactome:REACT_15434 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0005741 |
mitochondrial outer membrane |
Reactome:REACT_15485 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0005741 |
mitochondrial outer membrane |
Reactome:REACT_1795 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0005741 |
mitochondrial outer membrane |
Reactome:REACT_980 |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
||
| GO:0006576 |
cellular biogenic amine metabolic process |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0006584 |
catecholamine metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006805 |
xenobiotic metabolic process |
Reactome:REACT_13433 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0006805 |
xenobiotic metabolic process |
Reactome:REACT_13705 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0007268 |
synaptic transmission |
Reactome:REACT_13477 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0007268 |
synaptic transmission |
Reactome:REACT_13685 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0007269 |
neurotransmitter secretion |
Reactome:REACT_13723 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0007610 |
behavior |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0008131 |
primary amine oxidase activity |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000003910 |
F |
Seeded From UniProt |
|||
| GO:0008131 |
primary amine oxidase activity |
Reactome:REACT_15390 |
TAS: Traceable Author Statement |
|
F |
Seeded From UniProt |
||
| GO:0008131 |
primary amine oxidase activity |
Reactome:REACT_15434 |
TAS: Traceable Author Statement |
|
F |
Seeded From UniProt |
||
| GO:0008131 |
primary amine oxidase activity |
Reactome:REACT_15485 |
TAS: Traceable Author Statement |
|
F |
Seeded From UniProt |
||
| GO:0008131 |
primary amine oxidase activity |
Reactome:REACT_1795 |
TAS: Traceable Author Statement |
|
F |
Seeded From UniProt |
||
| GO:0008131 |
primary amine oxidase activity |
Reactome:REACT_980 |
TAS: Traceable Author Statement |
|
F |
Seeded From UniProt |
||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016491 |
oxidoreductase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0016491 |
oxidoreductase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0016491 |
oxidoreductase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0042135 |
neurotransmitter catabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0042136 |
neurotransmitter biosynthetic process |
Reactome:REACT_13583 |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
||
| GO:0042420 |
dopamine catabolic process |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000026013 |
P |
Seeded From UniProt |
|||
| GO:0042428 |
serotonin metabolic process |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000003910 |
P |
Seeded From UniProt |
|||
| GO:0042443 |
phenylethylamine metabolic process |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000003910 |
P |
Seeded From UniProt |
|||
| GO:0050660 |
flavin adenine dinucleotide binding |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000003910 |
F |
Seeded From UniProt |
|||
| GO:0051378 |
serotonin binding |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000003910 |
F |
Seeded From UniProt |
|||
| GO:0055114 |
oxidation-reduction process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0055114 |
oxidation-reduction process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0055114 |
oxidation-reduction process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
| |||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Brunner HG et al. (1993) Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A. Science 262: 578-80 PubMed GONUTS page
