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HUMAN:AIP
Contents |
| Species (Taxon ID) | Homo sapiens (Human). ([1]) | |
| Gene Name(s) | AIP (synonyms: XAP2) | |
| Protein Name(s) | AH receptor-interacting protein
AIP Aryl-hydrocarbon receptor-interacting protein HBV X-associated protein 2 XAP-2 Immunophilin homolog ARA9 | |
| External Links | ||
| EMBL | U31913 U78521 AM236341 EF066502 EF066504 EF066505 EF066510 BC104827 BC104797 | |
| IPI | IPI00953925 | |
| RefSeq | NP_003968.2 | |
| UniGene | Hs.412433 | |
| ProteinModelPortal | O00170 | |
| SMR | O00170 | |
| IntAct | O00170 | |
| MINT | MINT-5000425 | |
| STRING | O00170 | |
| PhosphoSite | O00170 | |
| PRIDE | O00170 | |
| Ensembl | ENST00000279146 | |
| GeneID | 9049 | |
| KEGG | hsa:9049 | |
| UCSC | uc001olv.1 | |
| CTD | 9049 | |
| GeneCards | GC11P063579 | |
| H-InvDB | HIX0036007 | |
| HGNC | HGNC:358 | |
| HPA | HPA004063 | |
| MIM | 102200 219090 600634 605555 | |
| neXtProt | NX_O00170 | |
| Orphanet | 963 96254 | |
| PharmGKB | PA24652 | |
| GeneTree | ENSGT00390000001289 | |
| HOVERGEN | HBG004198 | |
| InParanoid | O00170 | |
| OMA | DWIQLDL | |
| OrthoDB | EOG4B5P5R | |
| NextBio | 33903 | |
| ArrayExpress | O00170 | |
| Bgee | O00170 | |
| CleanEx | HS_AIP | |
| Genevestigator | O00170 | |
| GermOnline | ENSG00000110711 | |
| GO | GO:0005634 GO:0036004 GO:0004871 GO:0003713 GO:0008134 GO:0051082 GO:0022417 GO:0006626 | |
| InterPro | IPR001179 IPR013026 IPR011990 IPR019734 | |
| Gene3D | G3DSA:1.25.40.10 | |
| Pfam | PF00254 | |
| PROSITE | PS50059 PS50005 PS50293 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003712 |
transcription cofactor activity |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000113807 |
F |
Seeded From UniProt |
|||
| GO:0003713 |
transcription coactivator activity |
TAS: Traceable Author Statement |
|
F |
Seeded From UniProt |
|||
| GO:0004871 |
signal transducer activity |
TAS: Traceable Author Statement |
|
F |
Seeded From UniProt |
|||
| GO:0005488 |
binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded From UniProt |
||||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded From UniProt |
||||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded From UniProt |
||||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
Seeded From UniProt |
||||
| GO:0005624 |
membrane fraction |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000113807 |
C |
Seeded From UniProt |
|||
| GO:0005634 |
nucleus |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0086 |
C |
Seeded From UniProt |
|||
| GO:0005737 |
cytoplasm |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0005737 |
cytoplasm |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
|||
| GO:0005829 |
cytosol |
TAS: Traceable Author Statement |
|
C |
Seeded From UniProt |
|||
| GO:0005829 |
cytosol |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0006457 |
protein folding |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006626 |
protein targeting to mitochondrion |
IDA: Inferred from Direct Assay |
|
P |
Seeded From UniProt |
|||
| GO:0006805 |
xenobiotic metabolic process |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000113807 |
P |
Seeded From UniProt |
|||
| GO:0007165 |
signal transduction |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0008134 |
transcription factor binding |
TAS: Traceable Author Statement |
|
F |
Seeded From UniProt |
|||
| GO:0010738 |
regulation of protein kinase A signaling cascade |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000000599 |
P |
Seeded From UniProt |
|||
| GO:0022417 |
protein maturation by protein folding |
IDA: Inferred from Direct Assay |
|
P |
Seeded From UniProt |
|||
| GO:0036004 |
GAF domain binding |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0044445 |
cytosolic part |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000000599 |
C |
Seeded From UniProt |
|||
| GO:0051082 |
unfolded protein binding |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0051344 |
negative regulation of cyclic-nucleotide phosphodiesterase activity |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000000599 |
P |
Seeded From UniProt |
|||
| GO:0005730 |
nucleolus |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0005886 |
plasma membrane |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Meyer BK et al. (1998) Hepatitis B virus X-associated protein 2 is a subunit of the unliganded aryl hydrocarbon receptor core complex and exhibits transcriptional enhancer activity. Mol Cell Biol 18: 978-88 PubMed GONUTS page
- ↑ 2.0 2.1 Carver LA & Bradfield CA (1997) Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo. J Biol Chem 272: 11452-6 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Yano M et al. (2003) AIP is a mitochondrial import mediator that binds to both import receptor Tom20 and preproteins. J Cell Biol 163: 45-56 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 de Oliveira SK et al. (2007) Phosphodiesterase 2A forms a complex with the co-chaperone XAP2 and regulates nuclear translocation of the aryl hydrocarbon receptor. J Biol Chem 282: 13656-63 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Barbe L et al. (2008) Toward a confocal subcellular atlas of the human proteome. Mol Cell Proteomics 7: 499-508 PubMed GONUTS page
- ↑ Kuzhandaivelu N et al. (1996) XAP2, a novel hepatitis B virus X-associated protein that inhibits X transactivation. Nucleic Acids Res 24: 4741-50 PubMed GONUTS page
