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HUMAN:AGRP
Contents |
| Species (Taxon ID) | Homo sapiens (Human). ([1]) | |
| Gene Name(s) | AGRP (synonyms: AGRT, ART) | |
| Protein Name(s) | Agouti-related protein | |
| External Links | ||
| EMBL | U88063 U89485 AF314194 AF281309 DQ374394 BC110443 | |
| IPI | IPI00010869 | |
| RefSeq | NP_001129.1 | |
| UniGene | Hs.104633 | |
| PDB | 1HYK 1MR0 2IQV | |
| PDBsum | 1HYK 1MR0 2IQV | |
| ProteinModelPortal | O00253 | |
| SMR | O00253 | |
| STRING | O00253 | |
| PRIDE | O00253 | |
| Ensembl | ENST00000290953 ENST00000393941 | |
| GeneID | 181 | |
| KEGG | hsa:181 | |
| UCSC | uc002etg.1 | |
| CTD | 181 | |
| GeneCards | GC16M053389 | |
| H-InvDB | HIX0202329 | |
| HGNC | HGNC:330 | |
| HPA | HPA041017 | |
| MIM | 601665 602311 | |
| neXtProt | NX_O00253 | |
| eggNOG | prNOG20473 | |
| GeneTree | ENSGT00510000048590 | |
| HOGENOM | HBG126983 | |
| HOVERGEN | HBG050467 | |
| InParanoid | O00253 | |
| OMA | HESCLGH | |
| OrthoDB | EOG4X3H2X | |
| PhylomeDB | O00253 | |
| Pathway_Interaction_DB | syndecan_3_pathway | |
| NextBio | 738 | |
| ArrayExpress | O00253 | |
| Bgee | O00253 | |
| CleanEx | HS_AGRP | |
| Genevestigator | O00253 | |
| GermOnline | ENSG00000159723 | |
| GO | GO:0005615 GO:0005796 GO:0005184 GO:0009755 GO:0007218 GO:0060259 | |
| InterPro | IPR007733 | |
| Gene3D | G3DSA:4.10.760.10 | |
| PANTHER | PTHR16551 | |
| Pfam | PF05039 | |
| SMART | SM00792 | |
| SUPFAM | SSF57055 | |
| PROSITE | PS60024 PS51150 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005102 |
receptor binding |
TAS: Traceable Author Statement |
|
F |
Seeded From UniProt |
|||
| GO:0005184 |
neuropeptide hormone activity |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0005184 |
neuropeptide hormone activity |
TAS: Traceable Author Statement |
|
F |
Seeded From UniProt |
|||
| GO:0005576 |
extracellular region |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005576 |
extracellular region |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005576 |
extracellular region |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0243 |
C |
Seeded From UniProt |
|||
| GO:0005615 |
extracellular space |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0005794 |
Golgi apparatus |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005796 |
Golgi lumen |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0133 |
C |
Seeded From UniProt |
|||
| GO:0005796 |
Golgi lumen |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0007218 |
neuropeptide signaling pathway |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000005849 |
P |
Seeded From UniProt |
|||
| GO:0007218 |
neuropeptide signaling pathway |
IDA: Inferred from Direct Assay |
|
P |
Seeded From UniProt |
|||
| GO:0007218 |
neuropeptide signaling pathway |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0007631 |
feeding behavior |
TAS: Traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0008343 |
adult feeding behavior |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000005849 |
P |
Seeded From UniProt |
|||
| GO:0009755 |
hormone-mediated signaling pathway |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0060259 |
regulation of feeding behavior |
IDA: Inferred from Direct Assay |
|
P |
Seeded From UniProt |
|||
| GO:0060259 |
regulation of feeding behavior |
IMP: Inferred from Mutant Phenotype |
P |
Based on Figure 4, which shows the difference in weight of mice with the gene and without. |
complete | |||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Yang YK et al. (1999) Contribution of melanocortin receptor exoloops to Agouti-related protein binding. J Biol Chem 274: 14100-6 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 de Rijke CE et al. (2005) Functional analysis of the Ala67Thr polymorphism in agouti related protein associated with anorexia nervosa and leanness. Biochem Pharmacol 70: 308-16 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Ollmann MM et al. (1997) Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein. Science 278: 135-8 PubMed GONUTS page
- ↑ Rossi M et al. (1998) A C-terminal fragment of Agouti-related protein increases feeding and antagonizes the effect of alpha-melanocyte stimulating hormone in vivo. Endocrinology 139: 4428-31 PubMed GONUTS page
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