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HORSE:EDNRB

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Contents

Species (Taxon ID) Equus caballus (Horse). ([1])
Gene Name(s) EDNRB
Protein Name(s) Endothelin B receptor

ET-B ET-BR Endothelin receptor non-selective type

External Links
EMBL AF019072
AF038900
RefSeq NP_001075306.1
UniGene Eca.13045
ProteinModelPortal O62709
STRING O62709
GeneID 100033875
KEGG ecb:100033875
CTD 1910
GeneTree ENSGT00550000074261
HOVERGEN HBG051443
InParanoid O62709
OrthoDB EOG45HRX3
GO GO:0016021
GO:0005886
InterPro IPR000276
IPR000499
IPR001112
IPR017452
KO K04198
Pfam PF00001
PRINTS PR00571
PR00366
PR00237
PROSITE PS00237
PS50262

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000022718

P

Seeded From UniProt

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000335311

P

Seeded From UniProt

GO:0001755

neural crest cell migration

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000022718

P

Seeded From UniProt

GO:0004871

signal transducer activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0807

F

Seeded From UniProt

GO:0004872

receptor activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0675

F

Seeded From UniProt

GO:0004930

G-protein coupled receptor activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0297

F

Seeded From UniProt

GO:0004962

endothelin receptor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000499

F

Seeded From UniProt

GO:0004962

endothelin receptor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001112

F

Seeded From UniProt

GO:0004962

endothelin receptor activity

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000022718

F

Seeded From UniProt

GO:0005886

plasma membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded From UniProt

GO:0005886

plasma membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0039

C

Seeded From UniProt

GO:0006885

regulation of pH

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000022718

P

Seeded From UniProt

GO:0007165

signal transduction

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0807

P

Seeded From UniProt

GO:0007186

G-protein coupled receptor signaling pathway

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000276

P

Seeded From UniProt

GO:0007186

G-protein coupled receptor signaling pathway

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000499

P

Seeded From UniProt

GO:0007186

G-protein coupled receptor signaling pathway

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001112

P

Seeded From UniProt

GO:0007186

G-protein coupled receptor signaling pathway

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0297

P

Seeded From UniProt

GO:0007186

G-protein coupled receptor signaling pathway

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000022718

P

Seeded From UniProt

GO:0007422

peripheral nervous system development

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000022718

P

Seeded From UniProt

GO:0007497

posterior midgut development

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000022718

P

Seeded From UniProt

GO:0008217

regulation of blood pressure

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000022718

P

Seeded From UniProt

GO:0014043

negative regulation of neuron maturation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000022718

P

Seeded From UniProt

GO:0014826

vein smooth muscle contraction

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000335311

P

Seeded From UniProt

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded From UniProt

GO:0016021

integral to membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000276

C

Seeded From UniProt

GO:0016021

integral to membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000499

C

Seeded From UniProt

GO:0016021

integral to membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001112

C

Seeded From UniProt

GO:0016021

integral to membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded From UniProt

GO:0017046

peptide hormone binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000335311

F

Seeded From UniProt

GO:0030318

melanocyte differentiation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000022718

P

Seeded From UniProt

GO:0032269

negative regulation of cellular protein metabolic process

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000335311

P

Seeded From UniProt

GO:0035645

enteric smooth muscle cell differentiation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000022718

P

Seeded From UniProt

GO:0042310

vasoconstriction

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000335311

P

Seeded From UniProt

GO:0043473

pigmentation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000022718

P

Seeded From UniProt

GO:0048066

developmental pigmentation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000022718

P

Seeded From UniProt

GO:0048246

macrophage chemotaxis

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000335311

P

Seeded From UniProt

Contributes to

GO:0090301

negative regulation of neural crest formation

PMID:9585428[1]

IMP: Inferred from Mutant Phenotype

P

A certain mutation to the EDNRB causes the Neural crest to develop improperly, causing an absence of submucosal and myenteric neuronal plexi from the jejunum to the rectum (aganglionosis).

complete

GO:0048484

enteric nervous system development

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000022718

P

Seeded From UniProt

Contributes to

GO:0043473

pigmentation

PMID:9585428[1]

IMP: Inferred from Mutant Phenotype

P

A specific mutation of EDNRB leads to white coat color in horses.

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Metallinos DL et al. (1998) A missense mutation in the endothelin-B receptor gene is associated with Lethal White Foal Syndrome: an equine version of Hirschsprung disease. Mamm Genome 9: 426-31 PubMed GONUTS page
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