HCVJF:POLG

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Species (Taxon ID)	Hepatitis C virus genotype 2a (isolate JFH-1) (HCV). ([1])
Gene Name(s)	No Information Provided.
Protein Name(s)	Genome polyprotein Core protein p21 Capsid protein C p21 Core protein p19 Envelope glycoprotein E1 gp32 gp35 Envelope glycoprotein E2 NS1 gp68 gp70 p7 Protease NS2-3 p23 Serine protease NS3 Hepacivirin NS3P p70 Non-structural protein 4A NS4A p8 Non-structural protein 4B NS4B p27 Non-structural protein 5A NS5A p56 RNA-directed RNA polymerase NS5B p68
External Links
EMBL	AB047639
PDB	2KZQ 2XXD 2XYM 3I5K
PDBsum	2KZQ 2XXD 2XYM 3I5K
ProteinModelPortal	Q99IB8
SMR	Q99IB8
DIP	DIP-48925N
euHCVdb	AB047639
GO	GO:0005789 GO:0044167 GO:0044186 GO:0044191 GO:0042025 GO:0044220 GO:0020002 GO:0016021 GO:0030529 GO:0019028 GO:0019031 GO:0055036 GO:0005524 GO:0008026 GO:0004197 GO:0005216 GO:0003723 GO:0003968 GO:0004252 GO:0070008 GO:0017124 GO:0005198 GO:0008270 GO:0006915 GO:0030683 GO:0006508 GO:0006355 GO:0006351 GO:0019087 GO:0019079
InterPro	IPR014001 IPR011492 IPR002521 IPR002522 IPR002519 IPR002531 IPR000745 IPR001490 IPR002868 IPR013193 IPR001650 IPR002518 IPR009003 IPR004109 IPR007094 IPR002166 IPR013192
Pfam	PF07652 PF01543 PF01542 PF01539 PF01560 PF01538 PF01006 PF01001 PF01506 PF08300 PF08301 PF02907 PF00998
ProDom	PD001388
SMART	SM00487
SUPFAM	SSF50494
PROSITE	PS51192 PS51194 PS50507

Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes
	GO:0000166	nucleotide binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0547	F	Seeded From UniProt
	GO:0003676	nucleic acid binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001650	F	Seeded From UniProt
	GO:0003676	nucleic acid binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0543	F	Seeded From UniProt
	GO:0003723	RNA binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002166	F	Seeded From UniProt
	GO:0003723	RNA binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0694	F	Seeded From UniProt
	GO:0003824	catalytic activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR009003	F	Seeded From UniProt
	GO:0003824	catalytic activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0511	F	Seeded From UniProt
	GO:0003968	RNA-directed RNA polymerase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001490	F	Seeded From UniProt
	GO:0003968	RNA-directed RNA polymerase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002166	F	Seeded From UniProt
	GO:0003968	RNA-directed RNA polymerase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002518	F	Seeded From UniProt
	GO:0003968	RNA-directed RNA polymerase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002868	F	Seeded From UniProt
	GO:0003968	RNA-directed RNA polymerase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007094	F	Seeded From UniProt
	GO:0003968	RNA-directed RNA polymerase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013192	F	Seeded From UniProt
	GO:0003968	RNA-directed RNA polymerase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013193	F	Seeded From UniProt
	GO:0003968	RNA-directed RNA polymerase activity	GO_REF:0000003	IEA: Inferred from Electronic Annotation	EC:2.7.7.48	F	Seeded From UniProt
	GO:0003968	RNA-directed RNA polymerase activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0696	F	Seeded From UniProt
	GO:0004197	cysteine-type endopeptidase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001490	F	Seeded From UniProt
	GO:0004197	cysteine-type endopeptidase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002518	F	Seeded From UniProt
	GO:0004197	cysteine-type endopeptidase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002868	F	Seeded From UniProt
	GO:0004197	cysteine-type endopeptidase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013193	F	Seeded From UniProt
	GO:0004252	serine-type endopeptidase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001490	F	Seeded From UniProt
	GO:0004252	serine-type endopeptidase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002518	F	Seeded From UniProt
	GO:0004252	serine-type endopeptidase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002868	F	Seeded From UniProt
	GO:0004252	serine-type endopeptidase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013192	F	Seeded From UniProt
	GO:0004252	serine-type endopeptidase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013193	F	Seeded From UniProt
	GO:0004386	helicase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001650	F	Seeded From UniProt
	GO:0004386	helicase activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0347	F	Seeded From UniProt
	GO:0005198	structural molecule activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002521	F	Seeded From UniProt
	GO:0005198	structural molecule activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002522	F	Seeded From UniProt
	GO:0005216	ion channel activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0407	F	Seeded From UniProt
	GO:0005524	ATP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001650	F	Seeded From UniProt
	GO:0005524	ATP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002166	F	Seeded From UniProt
	GO:0005524	ATP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011492	F	Seeded From UniProt
	GO:0005524	ATP binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0067	F	Seeded From UniProt
	GO:0005576	extracellular region	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013193	C	Seeded From UniProt
	GO:0005576	extracellular region	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0964	C	Seeded From UniProt
	GO:0005576	extracellular region	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0243	C	Seeded From UniProt
	GO:0005789	endoplasmic reticulum membrane	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013192	C	Seeded From UniProt
	GO:0005789	endoplasmic reticulum membrane	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013193	C	Seeded From UniProt
	GO:0006351	transcription, DNA-dependent	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002166	P	Seeded From UniProt
	GO:0006351	transcription, DNA-dependent	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0804	P	Seeded From UniProt
	GO:0006355	regulation of transcription, DNA-dependent	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013192	P	Seeded From UniProt
	GO:0006355	regulation of transcription, DNA-dependent	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013193	P	Seeded From UniProt
	GO:0006355	regulation of transcription, DNA-dependent	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0805	P	Seeded From UniProt
	GO:0006508	proteolysis	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004109	P	Seeded From UniProt
	GO:0006810	transport	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0813	P	Seeded From UniProt
	GO:0006811	ion transport	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0406	P	Seeded From UniProt
	GO:0006915	apoptosis	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013192	P	Seeded From UniProt
	GO:0006915	apoptosis	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013193	P	Seeded From UniProt
	GO:0006915	apoptosis	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0053	P	Seeded From UniProt
	GO:0008026	ATP-dependent helicase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011492	F	Seeded From UniProt
	GO:0008152	metabolic process	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0511	P	Seeded From UniProt
	GO:0008233	peptidase activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0645	F	Seeded From UniProt
	GO:0008234	cysteine-type peptidase activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0788	F	Seeded From UniProt
	GO:0008236	serine-type peptidase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004109	F	Seeded From UniProt
	GO:0008236	serine-type peptidase activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0720	F	Seeded From UniProt
	GO:0008270	zinc ion binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013192	F	Seeded From UniProt
	GO:0008270	zinc ion binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013193	F	Seeded From UniProt
	GO:0016020	membrane	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0472	C	Seeded From UniProt
	GO:0016021	integral to membrane	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013192	C	Seeded From UniProt
	GO:0016021	integral to membrane	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013193	C	Seeded From UniProt
	GO:0016021	integral to membrane	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0812	C	Seeded From UniProt
	GO:0016032	viral reproduction	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000745	P	Seeded From UniProt
	GO:0016740	transferase activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0808	F	Seeded From UniProt
	GO:0016779	nucleotidyltransferase activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0548	F	Seeded From UniProt
	GO:0016787	hydrolase activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0378	F	Seeded From UniProt
	GO:0016817	hydrolase activity, acting on acid anhydrides	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002518	F	Seeded From UniProt
	GO:0017111	nucleoside-triphosphatase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001490	F	Seeded From UniProt
	GO:0017111	nucleoside-triphosphatase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002518	F	Seeded From UniProt
	GO:0017111	nucleoside-triphosphatase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002868	F	Seeded From UniProt
	GO:0017111	nucleoside-triphosphatase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013192	F	Seeded From UniProt
	GO:0017111	nucleoside-triphosphatase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013193	F	Seeded From UniProt
	GO:0017111	nucleoside-triphosphatase activity	GO_REF:0000003	IEA: Inferred from Electronic Annotation	EC:3.6.1.15	F	Seeded From UniProt
	GO:0017124	SH3 domain binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0729	F	Seeded From UniProt
	GO:0019012	virion	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0946	C	Seeded From UniProt
	GO:0019012	virion	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0274	C	Seeded From UniProt
	GO:0019028	viral capsid	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002522	C	Seeded From UniProt
	GO:0019028	viral capsid	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0167	C	Seeded From UniProt
	GO:0019031	viral envelope	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002519	C	Seeded From UniProt
	GO:0019079	viral genome replication	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002166	P	Seeded From UniProt
	GO:0019079	viral genome replication	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR007094	P	Seeded From UniProt
	GO:0019079	viral genome replication	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011492	P	Seeded From UniProt
	GO:0019087	transformation of host cell by virus	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004109	P	Seeded From UniProt
	GO:0020002	host cell plasma membrane	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-1032	C	Seeded From UniProt
	GO:0020002	host cell plasma membrane	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0375	C	Seeded From UniProt
	GO:0030430	host cell cytoplasm	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-1035	C	Seeded From UniProt
	GO:0030430	host cell cytoplasm	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0381	C	Seeded From UniProt
	GO:0030529	ribonucleoprotein complex	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0687	C	Seeded From UniProt
	GO:0030683	evasion by virus of host immune response	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013192	P	Seeded From UniProt
	GO:0030683	evasion by virus of host immune response	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013193	P	Seeded From UniProt
	GO:0030683	evasion by virus of host immune response	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0899	P	Seeded From UniProt
	GO:0030683	evasion by virus of host immune response	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0922	P	Seeded From UniProt
	GO:0032774	RNA biosynthetic process	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0693	P	Seeded From UniProt
	GO:0033644	host cell membrane	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-1043	C	Seeded From UniProt
	GO:0033650	host cell mitochondrion	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-1045	C	Seeded From UniProt
	GO:0033650	host cell mitochondrion	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0407	C	Seeded From UniProt
	GO:0042025	host cell nucleus	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-1048	C	Seeded From UniProt
	GO:0042025	host cell nucleus	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0414	C	Seeded From UniProt
	GO:0044165	host cell endoplasmic reticulum	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-1038	C	Seeded From UniProt
	GO:0044167	host cell endoplasmic reticulum membrane	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0390	C	Seeded From UniProt
	GO:0044186	host cell lipid particle	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-1041	C	Seeded From UniProt
	GO:0044186	host cell lipid particle	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0401	C	Seeded From UniProt
	GO:0044191	host cell mitochondrial membrane	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0410	C	Seeded From UniProt
	GO:0044220	host cell perinuclear region of cytoplasm	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0382	C	Seeded From UniProt
	GO:0044419	interspecies interaction between organisms	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0945	P	Seeded From UniProt
	GO:0044423	virion part	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000745	C	Seeded From UniProt
	GO:0046872	metal ion binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0479	F	Seeded From UniProt
	GO:0055036	virion membrane	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0275	C	Seeded From UniProt
	GO:0070008	serine-type exopeptidase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002518	F	Seeded From UniProt
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HCVJF:POLG

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