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HAEDU:Q9ZHL3
Contents |
| Species (Taxon ID) | Haemophilus ducreyi. (taxon:730) | |
| Gene Name(s) | lspA1 | |
| Protein Name(s) |
| |
| External Links | ||
| UniProt Identifier | Q9ZHL3_HAEDU | |
| UniProt Accessions | Q9ZHL3, | |
| EMBL | AF057695, | |
| PIR | T31102, | |
| Pfam | PF05594, PF05860, PF03543, | |
Annotations
| Qualifier | GO ID | GO term name | Reference(s) | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004197 |
cysteine-type endopeptidase activity |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0004197 |
cysteine-type endopeptidase activity |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0005488 |
binding |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0009405 |
pathogenesis |
IMP: Inferred from Mutant Phenotype |
P |
Table 2. In rabbit model, the lspA1 mutant yielded lesion scores that were lower than those obtained with the wild-type parent strain. While these differences were modest, they were nonetheless significant. |
complete | |||
| GO:0050765 |
negative regulation of phagocytosis |
IMP: Inferred from Mutant Phenotype |
P |
Enables resistance to phagocytosis along with LspA2. Figure 5. The lspA1 lspA2 mutant lost ability to resist phagocytosis. |
complete | |||
| GO:0004197 |
cysteine-type endopeptidase activity |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0004197 |
cysteine-type endopeptidase activity |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0005488 |
binding |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0009405 |
pathogenesis |
IEA: Inferred from Electronic Annotation |
P |
| ||||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Ward CK et al. (2003) Mutations in the lspA1 and lspA2 genes of Haemophilus ducreyi affect the virulence of this pathogen in an animal model system. Infect Immun 71: 2478-86 PubMed GONUTS page
- ↑ Vakevainen M et al. (2003) Inhibition of phagocytosis by Haemophilus ducreyi requires expression of the LspA1 and LspA2 proteins. Infect Immun 71: 5994-6003 PubMed GONUTS page
