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FB:yki
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | yki ( synonyms: CG4005, YKI, Yki, Yorkie, yap ) | |
| Protein Name(s) | yorkie, | |
| External Links | ||
| FB | FBgn0034970 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0002011 |
morphogenesis of an epithelial sheet |
FB:FBrf0193861 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0003713 |
transcription coactivator activity |
FB:FBrf0189460 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0003713 |
transcription coactivator activity |
FB:FBrf0204309 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0004842 |
ubiquitin-protein ligase activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
SGD:S0000927 |
F |
From FB |
||
| GO:0005634 |
nucleus |
FB:FBrf0204309 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0204309 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0007468 |
regulation of rhodopsin gene expression |
FB:FBrf0189460 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0008134 |
transcription factor binding |
FB:FBrf0204309 |
IPI: Inferred from Physical Interaction |
FB:FBgn0003345 |
F |
From FB |
||
| GO:0008283 |
cell proliferation |
FB:FBrf0187228 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008283 |
cell proliferation |
FB:FBrf0193861 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035212 |
cell competition in a multicellular organism |
FB:FBrf0211944 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0040008 |
regulation of growth |
FB:FBrf0194704 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043066 |
negative regulation of apoptotic process |
FB:FBrf0187228 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043066 |
negative regulation of apoptotic process |
FB:FBrf0193861 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
FB:FBrf0204309 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0072089 |
stem cell proliferation |
FB:FBrf0212502 |
IDA: Inferred from Direct Assay |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Thompson BJ & Cohen SM (2006) The Hippo pathway regulates the bantam microRNA to control cell proliferation and apoptosis in Drosophila. Cell 126: 767-74 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Goulev Y et al. (2008) SCALLOPED interacts with YORKIE, the nuclear effector of the hippo tumor-suppressor pathway in Drosophila. Curr Biol 18: 435-41 PubMed GONUTS page
- ↑ 3.0 3.1 Huang J et al. (2005) The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP. Cell 122: 421-34 PubMed GONUTS page
- ↑ Ziosi M et al. (2010) dMyc functions downstream of Yorkie to promote the supercompetitive behavior of hippo pathway mutant cells. PLoS Genet 6: PubMed GONUTS page
- ↑ Nolo R et al. (2006) The bantam microRNA is a target of the hippo tumor-suppressor pathway. Curr Biol 16: 1895-904 PubMed GONUTS page
- ↑ Ren F et al. (2010) Hippo signaling regulates Drosophila intestine stem cell proliferation through multiple pathways. Proc Natl Acad Sci U S A 107: 21064-9 PubMed GONUTS page
