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FB:wun

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) wun ( synonyms: CG8804, LPP-like, Wun, Wunen, l(2)k16806 )
Protein Name(s) wunen,
External Links
FB FBgn0016078

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005886

plasma membrane

FB:FBrf0091204
PMID:8985246[1]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0007280

pole cell migration

FB:FBrf0102832
PMID:9637912[2]

TAS: Traceable Author Statement

P

From FB

GO:0008195

phosphatidate phosphatase activity

FB:FBrf0106629

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0008195

phosphatidate phosphatase activity

FB:FBrf0132098
PMID:10908587[3]

NAS: Non-traceable Author Statement

F

From FB

GO:0008195

phosphatidate phosphatase activity

FB:FBrf0157009

NAS: Non-traceable Author Statement

F

From FB

GO:0008354

germ cell migration

FB:FBrf0091204
PMID:8985246[1]

NAS: Non-traceable Author Statement

P

From FB

GO:0008354

germ cell migration

FB:FBrf0107500
PMID:9988212[4]

TAS: Traceable Author Statement

P

From FB

GO:0008354

germ cell migration

FB:FBrf0142014

NAS: Non-traceable Author Statement

P

From FB

GO:0008354

germ cell migration

FB:FBrf0151867
PMID:12372264[5]

TAS: Traceable Author Statement

P

From FB

GO:0008354

germ cell migration

FB:FBrf0190943
PMID:16301333[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0009880

embryonic pattern specification

FB:FBrf0179398
PMID:15271294[7]

TAS: Traceable Author Statement

P

From FB

GO:0016020

membrane

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000326

C

From FB

GO:0016021

integral to membrane

FB:FBrf0157009

NAS: Non-traceable Author Statement

C

From FB

GO:0016311

dephosphorylation

FB:FBrf0132098
PMID:10908587[3]

NAS: Non-traceable Author Statement

P

From FB

GO:0016311

dephosphorylation

FB:FBrf0157009

NAS: Non-traceable Author Statement

P

From FB

GO:0016791

phosphatase activity

FB:FBrf0162096
PMID:12856002[8]

IDA: Inferred from Direct Assay

F

From FB

GO:0035233

germ cell repulsion

FB:FBrf0160454
PMID:12814944[9]

TAS: Traceable Author Statement

P

From FB

GO:0035233

germ cell repulsion

FB:FBrf0160886
PMID:12885551[10]

TAS: Traceable Author Statement

P

From FB

GO:0035233

germ cell repulsion

FB:FBrf0162293
PMID:12878005[11]

TAS: Traceable Author Statement

P

From FB

GO:0035233

germ cell repulsion

FB:FBrf0179403
PMID:15196560[12]

TAS: Traceable Author Statement

P

From FB

GO:0035233

germ cell repulsion

FB:FBrf0190943
PMID:16301333[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035233

germ cell repulsion

FB:FBrf0210764
PMID:20431117[13]

IGI: Inferred from Genetic Interaction

FB:FBgn0041087

P

From FB

GO:0035234

germ cell programmed cell death

FB:FBrf0160454
PMID:12814944[9]

TAS: Traceable Author Statement

P

From FB

GO:0042803

protein homodimerization activity

FB:FBrf0179398
PMID:15271294[7]

TAS: Traceable Author Statement

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Zhang N et al. (1997) The Drosophila protein Wunen repels migrating germ cells. Nature 385: 64-7 PubMed GONUTS page
  2. Howard K (1998) Organogenesis: Drosophila goes gonadal. Curr Biol 8: R415-7 PubMed GONUTS page
  3. 3.0 3.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
  4. Wylie C (1999) Germ cells. Cell 96: 165-74 PubMed GONUTS page
  5. Müller HA (2002) Germ cell migration: as slow as molasses. Curr Biol 12: R612-4 PubMed GONUTS page
  6. 6.0 6.1 Sano H et al. (2005) Control of lateral migration and germ cell elimination by the Drosophila melanogaster lipid phosphate phosphatases Wunen and Wunen 2. J Cell Biol 171: 675-83 PubMed GONUTS page
  7. 7.0 7.1 Pyne S et al. (2004) Lysophosphatidic acid and sphingosine 1-phosphate biology: the role of lipid phosphate phosphatases. Semin Cell Dev Biol 15: 491-501 PubMed GONUTS page
  8. Burnett C & Howard K (2003) Fly and mammalian lipid phosphate phosphatase isoforms differ in activity both in vitro and in vivo. EMBO Rep 4: 793-9 PubMed GONUTS page
  9. 9.0 9.1 Coffman CR (2003) Cell migration and programmed cell death of Drosophila germ cells. Ann N Y Acad Sci 995: 117-26 PubMed GONUTS page
  10. Ribeiro C et al. (2003) Signaling systems, guided cell migration, and organogenesis: insights from genetic studies in Drosophila. Dev Biol 260: 1-8 PubMed GONUTS page
  11. Luquain C et al. (2003) Lysophosphatidic acid signaling: how a small lipid does big things. Trends Biochem Sci 28: 377-83 PubMed GONUTS page
  12. Raz E (2004) Guidance of primordial germ cell migration. Curr Opin Cell Biol 16: 169-73 PubMed GONUTS page
  13. Renault AD et al. (2010) Lipid phosphate phosphatase activity regulates dispersal and bilateral sorting of embryonic germ cells in Drosophila. Development 137: 1815-23 PubMed GONUTS page
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