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FB:usp
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | usp ( synonyms: 2C, CF1, CF1/USP, CF1/Usp, CG4380, Cf1, Chorion factor 1, DmUSP, DmUsp, EG:22E5.1, NR2B4, USP, Ultraspiracle, Ultraspiricle, Usp, X receptor at 2C, XR2C, cf1, chorion factor CF1, dUSP, dmUSP, l(1)2Cf, l(1)usp ) | |
| Protein Name(s) | ultraspiracle, | |
| External Links | ||
| FB | FBgn0003964 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003677 |
DNA binding |
FB:FBrf0123719 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0004879 |
ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0004879 |
ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity |
FB:FBrf0138424 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004884 |
ecdysteroid hormone receptor activity |
FB:FBrf0057505 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0004884 |
ecdysteroid hormone receptor activity |
FB:FBrf0123719 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005500 |
juvenile hormone binding |
FB:FBrf0173271 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0167527 |
IPI: Inferred from Physical Interaction |
FB:FBgn0250850 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0192183 |
IPI: Inferred from Physical Interaction |
FB:FBgn0086908 |
F |
From FB |
||
| GO:0005634 |
nucleus |
FB:FBrf0057505 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0123719 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005700 |
polytene chromosome |
FB:FBrf0129910 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR000003 |
P |
From FB |
||
| GO:0007281 |
germ cell development |
FB:FBrf0213531 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007298 |
border follicle cell migration |
FB:FBrf0132259 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007517 |
muscle organ development |
FB:FBrf0190556 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007552 |
metamorphosis |
FB:FBrf0123719 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0008230 |
ecdysone receptor holocomplex |
FB:FBrf0086205 |
IPI: Inferred from Physical Interaction |
FB:FBgn0000546 |
C |
From FB |
||
| GO:0008230 |
ecdysone receptor holocomplex |
FB:FBrf0133206 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0008270 |
zinc ion binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0008289 |
lipid binding |
FB:FBrf0135920 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0016322 |
neuron remodeling |
FB:FBrf0132434 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016322 |
neuron remodeling |
FB:FBrf0174492 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030425 |
dendrite |
FB:FBrf0191447 |
IMP: Inferred from Mutant Phenotype |
C |
From FB |
|||
| GO:0035072 |
ecdysone-mediated induction of salivary gland cell autophagic cell death |
FB:FBrf0133206 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0040034 |
regulation of development, heterochronic |
FB:FBrf0141454 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0042803 |
protein homodimerization activity |
FB:FBrf0206889 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0043401 |
steroid hormone mediated signaling pathway |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0043565 |
sequence-specific DNA binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0045596 |
negative regulation of cell differentiation |
FB:FBrf0129910 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
FB:FBrf0129910 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
FB:FBrf0173271 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0046982 |
protein heterodimerization activity |
FB:FBrf0086205 |
IPI: Inferred from Physical Interaction |
FB:FBgn0000546 |
F |
From FB |
||
| GO:0046982 |
protein heterodimerization activity |
FB:FBrf0206889 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0048666 |
neuron development |
FB:FBrf0190556 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048813 |
dendrite morphogenesis |
FB:FBrf0174512 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0048813 |
dendrite morphogenesis |
FB:FBrf0190556 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
|
contributes_to |
GO:0001077 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription |
FB:FBrf0086205 |
IPI: Inferred from Physical Interaction |
FB:FBgn0000546 |
F |
From FB |
|
|
contributes_to |
GO:0004884 |
ecdysteroid hormone receptor activity |
FB:FBrf0086205 |
IPI: Inferred from Physical Interaction |
FB:FBgn0000546 |
F |
From FB |
|
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Maglich JM et al. (2001) Comparison of complete nuclear receptor sets from the human, Caenorhabditis elegans and Drosophila genomes. Genome Biol 2: RESEARCH0029 PubMed GONUTS page
- ↑ 2.0 2.1 Christianson AM et al. (1992) DNA binding and heteromerization of the Drosophila transcription factor chorion factor 1/ultraspiracle. Proc Natl Acad Sci U S A 89: 11503-7 PubMed GONUTS page
- ↑ 3.0 3.1 Wheeler DE & Nijhout HF (2003) A perspective for understanding the modes of juvenile hormone action as a lipid signaling system. Bioessays 25: 994-1001 PubMed GONUTS page
- ↑ Gates J et al. (2004) rigor mortis encodes a novel nuclear receptor interacting protein required for ecdysone signaling during Drosophila larval development. Development 131: 25-36 PubMed GONUTS page
- ↑ Stabell M et al. (2006) The Drosophila SET domain encoding gene dEset is essential for proper development. Hereditas 143: 177-88 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Kozlova T & Thummel CS (2000) Steroid regulation of postembryonic development and reproduction in Drosophila. Trends Endocrinol Metab 11: 276-80 PubMed GONUTS page
- ↑ König A et al. (2011) Ecdysteroids affect Drosophila ovarian stem cell niche formation and early germline differentiation. EMBO J 30: 1549-62 PubMed GONUTS page
- ↑ Bai J et al. (2000) Regulation of invasive cell behavior by taiman, a Drosophila protein related to AIB1, a steroid receptor coactivator amplified in breast cancer. Cell 103: 1047-58 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 Parrish JZ et al. (2006) Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. Genes Dev 20: 820-35 PubMed GONUTS page
- ↑ 10.0 10.1 10.2 10.3 Zelhof AC et al. (1995) Seven-up inhibits ultraspiracle-based signaling pathways in vitro and in vivo. Mol Cell Biol 15: 6736-45 PubMed GONUTS page
- ↑ 11.0 11.1 Buszczak M & Segraves WA (2000) Insect metamorphosis: out with the old, in with the new. Curr Biol 10: R830-3 PubMed GONUTS page
- ↑ Clayton GM et al. (2001) The structure of the ultraspiracle ligand-binding domain reveals a nuclear receptor locked in an inactive conformation. Proc Natl Acad Sci U S A 98: 1549-54 PubMed GONUTS page
- ↑ Lee T et al. (2000) Cell-autonomous requirement of the USP/EcR-B ecdysone receptor for mushroom body neuronal remodeling in Drosophila. Neuron 28: 807-18 PubMed GONUTS page
- ↑ Awasaki T & Ito K (2004) Engulfing action of glial cells is required for programmed axon pruning during Drosophila metamorphosis. Curr Biol 14: 668-77 PubMed GONUTS page
- ↑ Kuo CT et al. (2005) Dendrite-specific remodeling of Drosophila sensory neurons requires matrix metalloproteases, ubiquitin-proteasome, and ecdysone signaling. Proc Natl Acad Sci U S A 102: 15230-5 PubMed GONUTS page
- ↑ Thummel CS (2001) Molecular mechanisms of developmental timing in C. elegans and Drosophila. Dev Cell 1: 453-65 PubMed GONUTS page
- ↑ 17.0 17.1 Bitra K & Palli SR (2009) Interaction of proteins involved in ecdysone and juvenile hormone signal transduction. Arch Insect Biochem Physiol 70: 90-105 PubMed GONUTS page
- ↑ Grueber WB & Jan YN (2004) Dendritic development: lessons from Drosophila and related branches. Curr Opin Neurobiol 14: 74-82 PubMed GONUTS page
