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FB:ush
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | ush ( synonyms: CG2762, Drosophila Friend of GATA, FOG, Friend of GATA, U-shaped, Ush, dFOG, l(2)19, u-sh, ushaped ) | |
| Protein Name(s) | u-shaped, | |
| External Links | ||
| FB | FBgn0003963 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
FB:FBrf0099172 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0001102 |
RNA polymerase II activating transcription factor binding |
FB:FBrf0099243 |
IPI: Inferred from Physical Interaction |
FB:FBgn0003117 |
F |
From FB |
||
| GO:0002805 |
regulation of antimicrobial peptide biosynthetic process |
FB:FBrf0210846 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0003676 |
nucleic acid binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0105495 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004879 |
ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity |
FB:FBrf0105495 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0151958 |
IPI: Inferred from Physical Interaction |
FB:FBgn0003507 |
F |
From FB |
||
| GO:0005634 |
nucleus |
FB:FBrf0099172 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0105495 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
FB:FBrf0099172 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
FB:FBrf0151872 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007362 |
terminal region determination |
FB:FBrf0054989 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003733 |
P |
From FB |
||
| GO:0007390 |
germ-band shortening |
FB:FBrf0087131 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007390 |
germ-band shortening |
FB:FBrf0090577 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007390 |
germ-band shortening |
FB:FBrf0111406 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007390 |
germ-band shortening |
FB:FBrf0151280 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007391 |
dorsal closure |
FB:FBrf0151280 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007393 |
dorsal closure, leading edge cell fate determination |
FB:FBrf0138365 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007398 |
ectoderm development |
FB:FBrf0168049 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007507 |
heart development |
FB:FBrf0137102 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007507 |
heart development |
FB:FBrf0151249 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008134 |
transcription factor binding |
FB:FBrf0099172 |
IMP: Inferred from Mutant Phenotype |
F |
From FB |
|||
| GO:0008134 |
transcription factor binding |
FB:FBrf0158758 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0008258 |
head involution |
FB:FBrf0087131 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0008270 |
zinc ion binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0008293 |
torso signaling pathway |
FB:FBrf0054989 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003733 |
P |
From FB |
||
| GO:0009996 |
negative regulation of cell fate specification |
FB:FBrf0167476 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0030097 |
hemopoiesis |
FB:FBrf0144845 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035167 |
larval lymph gland hemopoiesis |
FB:FBrf0201267 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035167 |
larval lymph gland hemopoiesis |
FB:FBrf0208909 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042440 |
pigment metabolic process |
FB:FBrf0151319 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0042690 |
negative regulation of crystal cell differentiation |
FB:FBrf0158758 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0042690 |
negative regulation of crystal cell differentiation |
FB:FBrf0167434 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0042690 |
negative regulation of crystal cell differentiation |
FB:FBrf0167476 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0043433 |
negative regulation of sequence-specific DNA binding transcription factor activity |
FB:FBrf0099243 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0046665 |
amnioserosa maintenance |
FB:FBrf0087131 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046665 |
amnioserosa maintenance |
FB:FBrf0138365 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0046665 |
amnioserosa maintenance |
FB:FBrf0168049 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048542 |
lymph gland development |
FB:FBrf0195108 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048749 |
compound eye development |
FB:FBrf0137102 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Cubadda Y et al. (1997) u-shaped encodes a zinc finger protein that regulates the proneural genes achaete and scute during the formation of bristles in Drosophila. Genes Dev 11: 3083-95 PubMed GONUTS page
- ↑ 2.0 2.1 Haenlin M et al. (1997) Transcriptional activity of pannier is regulated negatively by heterodimerization of the GATA DNA-binding domain with a cofactor encoded by the u-shaped gene of Drosophila. Genes Dev 11: 3096-108 PubMed GONUTS page
- ↑ Valanne S et al. (2010) Genome-wide RNA interference in Drosophila cells identifies G protein-coupled receptor kinase 2 as a conserved regulator of NF-kappaB signaling. J Immunol 184: 6188-98 PubMed GONUTS page
- ↑ Waltzer L et al. (2002) Two isoforms of Serpent containing either one or two GATA zinc fingers have different roles in Drosophila haematopoiesis. EMBO J 21: 5477-86 PubMed GONUTS page
- ↑ Martin P & Wood W (2002) Epithelial fusions in the embryo. Curr Opin Cell Biol 14: 569-74 PubMed GONUTS page
- ↑ 6.0 6.1 Strecker TR et al. (1991) Zygotic genes that mediate torso receptor tyrosine kinase functions in the Drosophila melanogaster embryo. Proc Natl Acad Sci U S A 88: 5824-8 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Frank LH & Rushlow C (1996) A group of genes required for maintenance of the amnioserosa tissue in Drosophila. Development 122: 1343-52 PubMed GONUTS page
- ↑ Goldman-Levi R et al. (1996) Cellular pathways acting along the germband and in the amnioserosa may participate in germband retraction of the Drosophila melanogaster embryo. Int J Dev Biol 40: 1043-51 PubMed GONUTS page
- ↑ Lamka ML & Lipshitz HD (1999) Role of the amnioserosa in germ band retraction of the Drosophila melanogaster embryo. Dev Biol 214: 102-12 PubMed GONUTS page
- ↑ 10.0 10.1 Harden N (2002) Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila. Differentiation 70: 181-203 PubMed GONUTS page
- ↑ 11.0 11.1 Stronach BE & Perrimon N (2001) Investigation of leading edge formation at the interface of amnioserosa and dorsal ectoderm in the Drosophila embryo. Development 128: 2905-13 PubMed GONUTS page
- ↑ 12.0 12.1 Raftery LA & Sutherland DJ (2003) Gradients and thresholds: BMP response gradients unveiled in Drosophila embryos. Trends Genet 19: 701-8 PubMed GONUTS page
- ↑ 13.0 13.1 Fossett N et al. (2001) The Friend of GATA proteins U-shaped, FOG-1, and FOG-2 function as negative regulators of blood, heart, and eye development in Drosophila. Proc Natl Acad Sci U S A 98: 7342-7 PubMed GONUTS page
- ↑ Cripps RM & Olson EN (2002) Control of cardiac development by an evolutionarily conserved transcriptional network. Dev Biol 246: 14-28 PubMed GONUTS page
- ↑ 15.0 15.1 Evans CJ & Banerjee U (2003) Transcriptional regulation of hematopoiesis in Drosophila. Blood Cells Mol Dis 30: 223-8 PubMed GONUTS page
- ↑ 16.0 16.1 Evans CJ et al. (2003) Thicker than blood: conserved mechanisms in Drosophila and vertebrate hematopoiesis. Dev Cell 5: 673-90 PubMed GONUTS page
- ↑ Fossett N & Schulz RA (2001) Functional conservation of hematopoietic factors in Drosophila and vertebrates. Differentiation 69: 83-90 PubMed GONUTS page
- ↑ Sorrentino RP et al. (2007) The Friend of GATA protein U-shaped functions as a hematopoietic tumor suppressor in Drosophila. Dev Biol 311: 311-23 PubMed GONUTS page
- ↑ Gao H et al. (2009) Upregulation of the Drosophila Friend of GATA gene U-shaped by JAK/STAT signaling maintains lymph gland prohemocyte potency. Mol Cell Biol 29: 6086-96 PubMed GONUTS page
- ↑ Calleja M et al. (2002) How to pattern an epithelium: lessons from achaete-scute regulation on the notum of Drosophila. Gene 292: 1-12 PubMed GONUTS page
- ↑ Meister M (2004) Blood cells of Drosophila: cell lineages and role in host defence. Curr Opin Immunol 16: 10-5 PubMed GONUTS page
- ↑ Muratoglu S et al. (2006) Regulation of Drosophila friend of GATA gene, u-shaped, during hematopoiesis: a direct role for serpent and lozenge. Dev Biol 296: 561-79 PubMed GONUTS page
