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FB:tws
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | tws ( synonyms: 1466/06, 2414, B/PR55, CG6235, DPR55, PP2A, PP2A regulatory subunit, PP2A regulatory subunit Twins, PP2A(B), PP2a, PR55, Pp2A-85F, Protein phosphatase 2A at 85F, Twins, Tws, aar, abnormal anaphase resolution, dPP2A, dPR55, l(3)01436, l(3)02414, l(3)S022205b, l(3)S022361, l(3)S022440, l(3)S023013, l(3)S023141a, l(3)S023206, l(3)S023309, l(3)S023938, l(3)S024455, l(3)S024834a, l(3)S024838, l(3)S025806, l(3)S025832, l(3)S025913, l(3)S026226, l(3)S026326, l(3)S027127, l(3)S027313, l(3)S028707, l(3)S029110, l(3)S029403, l(3)S029701a, l(3)S031006, l(3)S032303, l(3)S032708c, l(3)S033903, l(3)S035505b, l(3)S042629, l(3)S042630, l(3)S043008b, l(3)S043029, l(3)S045519, l(3)S046918, l(3)S048006, l(3)S048013, l(3)S048507, l(3)S049902, l(3)S052810, l(3)S053011, l(3)S060203, l(3)S060804, l(3)S061805, l(3)S061915, l(3)S063110, l(3)S066017, l(3)S066813, l(3)S067109b, l(3)S067915, l(3)S069206a, l(3)S075110, l(3)S075515b, l(3)S075902b, l(3)S076415, l(3)S080409, l(3)S088513, l(3)S091905, l(3)S101413b, l(3)S105605, l(3)S110008a, l(3)S110815, l(3)S111515, l(3)S119908, l(3)S132907, l(3)S134601a, l(3)S141309, l(3)S146606, l(3)j11C8, l(3)s1801, phosphoprotein phosphatase 2A 55 kDa, protein phosphatase 2A, protein phosphatase 2a, protein phosphatase type 2A, regulatory B subunit of type 2A protein phosphatase, tw, tws/aar, v158 ) | |
| Protein Name(s) | twins, | |
| External Links | ||
| FB | FBgn0004889 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000090 |
mitotic anaphase |
FB:FBrf0057890 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000159 |
protein phosphatase type 2A complex |
FB:FBrf0058530 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0000159 |
protein phosphatase type 2A complex |
FB:FBrf0117810 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0000159 |
protein phosphatase type 2A complex |
FB:FBrf0156759 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0000159 |
protein phosphatase type 2A complex |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
C |
From FB |
|||
| GO:0000278 |
mitotic cell cycle |
FB:FBrf0192076 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0001700 |
embryonic development via the syncytial blastoderm |
FB:FBrf0091142 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0004722 |
protein serine/threonine phosphatase activity |
FB:FBrf0058530 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0207940 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0076752 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0207940 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005875 |
microtubule associated complex |
FB:FBrf0204649 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006470 |
protein dephosphorylation |
FB:FBrf0058530 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From FB |
|||
| GO:0006470 |
protein dephosphorylation |
FB:FBrf0117810 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007088 |
regulation of mitosis |
FB:FBrf0057890 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007406 |
negative regulation of neuroblast proliferation |
FB:FBrf0207940 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007423 |
sensory organ development |
FB:FBrf0074436 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007447 |
imaginal disc pattern formation |
FB:FBrf0058530 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008601 |
protein phosphatase type 2A regulator activity |
FB:FBrf0076752 |
IMP: Inferred from Mutant Phenotype |
F |
From FB |
|||
| GO:0008601 |
protein phosphatase type 2A regulator activity |
FB:FBrf0117810 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0008601 |
protein phosphatase type 2A regulator activity |
FB:FBrf0156759 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0016055 |
Wnt receptor signaling pathway |
FB:FBrf0174550 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0000499 |
P |
From FB |
||
| GO:0016055 |
Wnt receptor signaling pathway |
FB:FBrf0174550 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003371 |
P |
From FB |
||
| GO:0016055 |
Wnt receptor signaling pathway |
FB:FBrf0174550 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0085432 |
P |
From FB |
||
| GO:0016055 |
Wnt receptor signaling pathway |
FB:FBrf0174550 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045201 |
maintenance of neuroblast polarity |
FB:FBrf0207940 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Mayer-Jaekel RE et al. (1993) The 55 kd regulatory subunit of Drosophila protein phosphatase 2A is required for anaphase. Cell 72: 621-33 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Uemura T et al. (1993) Mutation of twins encoding a regulator of protein phosphatase 2A leads to pattern duplication in Drosophila imaginal discs. Genes Dev 7: 429-40 PubMed GONUTS page
- ↑ Chen F et al. (2007) Multiple protein phosphatases are required for mitosis in Drosophila. Curr Biol 17: 293-303 PubMed GONUTS page
- ↑ Perrimon N et al. (1996) Zygotic lethal mutations with maternal effect phenotypes in Drosophila melanogaster. II. Loci on the second and third chromosomes identified by P-element-induced mutations. Genetics 144: 1681-92 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 Chabu C & Doe CQ (2009) Twins/PP2A regulates aPKC to control neuroblast cell polarity and self-renewal. Dev Biol 330: 399-405 PubMed GONUTS page
- ↑ 6.0 6.1 Mayer-Jaekel RE et al. (1994) Drosophila mutants in the 55 kDa regulatory subunit of protein phosphatase 2A show strongly reduced ability to dephosphorylate substrates of p34cdc2. J Cell Sci 107 ( Pt 9): 2609-16 PubMed GONUTS page
- ↑ Hughes JR et al. (2008) A microtubule interactome: complexes with roles in cell cycle and mitosis. PLoS Biol 6: e98 PubMed GONUTS page
- ↑ Shiomi K et al. (1994) Alternative cell fate choice induced by low-level expression of a regulator of protein phosphatase 2A in the Drosophila peripheral nervous system. Development 120: 1591-9 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 9.3 Bajpai R et al. (2004) Drosophila Twins regulates Armadillo levels in response to Wg/Wnt signal. Development 131: 1007-16 PubMed GONUTS page
ceim |
m cont.np |
p cont.rsw |
