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FB:twi
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | twi ( synonyms: CG2956, DTwist, EC9, TWI, Tw, Twi, Twist, bHLHb17, dip5 ) | |
| Protein Name(s) | twist, | |
| External Links | ||
| FB | FBgn0003900 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001710 |
mesodermal cell fate commitment |
FB:FBrf0075064 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0001710 |
mesodermal cell fate commitment |
FB:FBrf0138533 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0001710 |
mesodermal cell fate commitment |
FB:FBrf0138569 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0003677 |
DNA binding |
FB:FBrf0123517 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0003677 |
DNA binding |
FB:FBrf0138569 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0003705 |
RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity |
FB:FBrf0100308 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0047934 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0123517 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0211995 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006357 |
regulation of transcription from RNA polymerase II promoter |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From FB |
|||
| GO:0007369 |
gastrulation |
FB:FBrf0110176 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007370 |
ventral furrow formation |
FB:FBrf0075064 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007375 |
anterior midgut invagination |
FB:FBrf0075064 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007435 |
salivary gland morphogenesis |
FB:FBrf0190174 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007443 |
Malpighian tubule morphogenesis |
FB:FBrf0111391 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007498 |
mesoderm development |
FB:FBrf0123517 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007498 |
mesoderm development |
FB:FBrf0130167 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007498 |
mesoderm development |
FB:FBrf0138533 |
IEP: Inferred from Expression Pattern |
P |
From FB |
|||
| GO:0007498 |
mesoderm development |
FB:FBrf0144780 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007498 |
mesoderm development |
FB:FBrf0151249 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007499 |
ectoderm and mesoderm interaction |
FB:FBrf0147042 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007500 |
mesodermal cell fate determination |
FB:FBrf0108595 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007501 |
mesodermal cell fate specification |
FB:FBrf0141281 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007501 |
mesodermal cell fate specification |
FB:FBrf0148941 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007507 |
heart development |
FB:FBrf0151249 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0009950 |
dorsal/ventral axis specification |
FB:FBrf0141281 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0010004 |
gastrulation involving germ band extension |
FB:FBrf0179905 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0010629 |
negative regulation of gene expression |
FB:FBrf0193889 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0016202 |
regulation of striated muscle tissue development |
FB:FBrf0138569 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0031032 |
actomyosin structure organization |
FB:FBrf0210158 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042803 |
protein homodimerization activity |
FB:FBrf0138569 |
IPI: Inferred from Physical Interaction |
F |
From FB |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
FB:FBrf0100308 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
FB:FBrf0110176 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
FB:FBrf0111461 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0046982 |
protein heterodimerization activity |
FB:FBrf0138569 |
IPI: Inferred from Physical Interaction |
F |
From FB |
|||
| GO:0048747 |
muscle fiber development |
FB:FBrf0190139 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
|
contributes_to |
GO:0003705 |
RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity |
FB:FBrf0155780 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0260632 |
F |
From FB |
|
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Furlong EE et al. (2001) Patterns of gene expression during Drosophila mesoderm development. Science 293: 1629-33 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Castanon I et al. (2001) Dimerization partners determine the activity of the Twist bHLH protein during Drosophila mesoderm development. Development 128: 3145-59 PubMed GONUTS page
- ↑ 3.0 3.1 Yin Z et al. (1997) Regulation of the twist target gene tinman by modular cis-regulatory elements during early mesoderm development. Development 124: 4971-82 PubMed GONUTS page
- ↑ Thisse B et al. (1988) Sequence of the twist gene and nuclear localization of its protein in endomesodermal cells of early Drosophila embryos. EMBO J 7: 2175-83 PubMed GONUTS page
- ↑ Tipping M et al. (2010) β-arrestin Kurtz inhibits MAPK and Toll signalling in Drosophila development. EMBO J 29: 3222-35 PubMed GONUTS page
- ↑ 6.0 6.1 Leptin M (1999) Gastrulation in Drosophila: the logic and the cellular mechanisms. EMBO J 18: 3187-92 PubMed GONUTS page
- ↑ Vining MS et al. (2005) Organ positioning in Drosophila requires complex tissue-tissue interactions. Dev Biol 287: 19-34 PubMed GONUTS page
- ↑ Jack J & Myette G (1999) Mutations that alter the morphology of the malpighian tubules in Drosophila. Dev Genes Evol 209: 546-54 PubMed GONUTS page
- ↑ Wilson R & Leptin M (2000) Fibroblast growth factor receptor-dependent morphogenesis of the Drosophila mesoderm. Philos Trans R Soc Lond B Biol Sci 355: 891-5 PubMed GONUTS page
- ↑ Taylor MV (2002) Drosophila development: novel signal elicits visceral response. Curr Biol 12: R102-4 PubMed GONUTS page
- ↑ 11.0 11.1 Cripps RM & Olson EN (2002) Control of cardiac development by an evolutionarily conserved transcriptional network. Dev Biol 246: 14-28 PubMed GONUTS page
- ↑ Stainier DY (2002) A glimpse into the molecular entrails of endoderm formation. Genes Dev 16: 893-907 PubMed GONUTS page
- ↑ Bate M et al. (1999) Development of larval body wall muscles. Int Rev Neurobiol 43: 25-44 PubMed GONUTS page
- ↑ 14.0 14.1 Lall S & Patel NH (2001) Conservation and divergence in molecular mechanisms of axis formation. Annu Rev Genet 35: 407-37 PubMed GONUTS page
- ↑ Stathopoulos A & Levine M (2002) Dorsal gradient networks in the Drosophila embryo. Dev Biol 246: 57-67 PubMed GONUTS page
- ↑ Stathopoulos A & Levine M (2004) Whole-genome analysis of Drosophila gastrulation. Curr Opin Genet Dev 14: 477-84 PubMed GONUTS page
- ↑ Anderson J et al. (2006) Regulation of the retinal determination gene dachshund in the embryonic head and developing eye of Drosophila. Dev Biol 297: 536-49 PubMed GONUTS page
- ↑ Martin AC et al. (2010) Integration of contractile forces during tissue invagination. J Cell Biol 188: 735-49 PubMed GONUTS page
- ↑ Postigo AA et al. (1999) zfh-1, the Drosophila homologue of ZEB, is a transcriptional repressor that regulates somatic myogenesis. Mol Cell Biol 19: 7255-63 PubMed GONUTS page
- ↑ Lovato TL et al. (2005) Transcription of Myocyte enhancer factor-2 in adult Drosophila myoblasts is induced by the steroid hormone ecdysone. Dev Biol 288: 612-21 PubMed GONUTS page
- ↑ Bhaskar V & Courey AJ (2002) The MADF-BESS domain factor Dip3 potentiates synergistic activation by Dorsal and Twist. Gene 299: 173-84 PubMed GONUTS page