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FB:tup

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) tup ( synonyms: CG10619, Isl, Islet, Islet 1, Tup, dIslet, isl, islet, l(2)37Aa, l(2)E41, lethal(2)37Aa, tailup/islet )
Protein Name(s) tailup,
External Links
FB FBgn0003896

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000977

RNA polymerase II regulatory region sequence-specific DNA binding

FB:FBrf0190092
PMID:16259974[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0000980

RNA polymerase II distal enhancer sequence-specific DNA binding

FB:FBrf0202097
PMID:17371844[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0001102

RNA polymerase II activating transcription factor binding

FB:FBrf0190092
PMID:16259974[1]

IPI: Inferred from Physical Interaction

FB:FBgn0003117

F

From FB

GO:0003705

RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity

FB:FBrf0202097
PMID:17371844[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0005515

protein binding

FB:FBrf0190092
PMID:16259974[1]

IPI: Inferred from Physical Interaction

FB:FBgn0013764

F

From FB

GO:0005634

nucleus

FB:FBrf0093227
PMID:9115734[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0005634

nucleus

FB:FBrf0202097
PMID:17371844[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0007362

terminal region determination

FB:FBrf0054989
PMID:1905816[4]

IGI: Inferred from Genetic Interaction

FB:FBgn0003733

P

From FB

GO:0007390

germ-band shortening

FB:FBrf0087131
PMID:8625823[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007390

germ-band shortening

FB:FBrf0090577
PMID:8946251[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007391

dorsal closure

FB:FBrf0190092
PMID:16259974[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007411

axon guidance

FB:FBrf0093227
PMID:9115734[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007507

heart development

FB:FBrf0202097
PMID:17371844[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008045

motor axon guidance

FB:FBrf0180170
PMID:15469973[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008258

head involution

FB:FBrf0087131
PMID:8625823[5]

NAS: Non-traceable Author Statement

P

From FB

GO:0008270

zinc ion binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001781

F

From FB

GO:0008293

torso signaling pathway

FB:FBrf0054989
PMID:1905816[4]

IGI: Inferred from Genetic Interaction

FB:FBgn0003733

P

From FB

GO:0008407

chaeta morphogenesis

FB:FBrf0190092
PMID:16259974[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0022416

chaeta development

FB:FBrf0212072
PMID:20580820[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035310

notum cell fate specification

FB:FBrf0201638
PMID:17409113[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0043433

negative regulation of sequence-specific DNA binding transcription factor activity

FB:FBrf0190092
PMID:16259974[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

FB:FBrf0202097
PMID:17371844[2]

IDA: Inferred from Direct Assay

P

From FB

GO:0046665

amnioserosa maintenance

FB:FBrf0087131
PMID:8625823[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048542

lymph gland development

FB:FBrf0202097
PMID:17371844[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0070983

dendrite guidance

FB:FBrf0195086
PMID:17276922[10]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 Biryukova I & Heitzler P (2005) The Drosophila LIM-homeo domain protein Islet antagonizes pro-neural cell specification in the peripheral nervous system. Dev Biol 288: 559-70 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Tao Y et al. (2007) Requirement of the LIM homeodomain transcription factor tailup for normal heart and hematopoietic organ formation in Drosophila melanogaster. Mol Cell Biol 27: 3962-9 PubMed GONUTS page
  3. 3.0 3.1 Thor S & Thomas JB (1997) The Drosophila islet gene governs axon pathfinding and neurotransmitter identity. Neuron 18: 397-409 PubMed GONUTS page
  4. 4.0 4.1 Strecker TR et al. (1991) Zygotic genes that mediate torso receptor tyrosine kinase functions in the Drosophila melanogaster embryo. Proc Natl Acad Sci U S A 88: 5824-8 PubMed GONUTS page
  5. 5.0 5.1 5.2 Frank LH & Rushlow C (1996) A group of genes required for maintenance of the amnioserosa tissue in Drosophila. Development 122: 1343-52 PubMed GONUTS page
  6. Goldman-Levi R et al. (1996) Cellular pathways acting along the germband and in the amnioserosa may participate in germband retraction of the Drosophila melanogaster embryo. Int J Dev Biol 40: 1043-51 PubMed GONUTS page
  7. Certel SJ & Thor S (2004) Specification of Drosophila motoneuron identity by the combinatorial action of POU and LIM-HD factors. Development 131: 5429-39 PubMed GONUTS page
  8. de Navascués J & Modolell J (2010) The pronotum LIM-HD gene tailup is both a positive and a negative regulator of the proneural genes achaete and scute of Drosophila. Mech Dev 127: 393-406 PubMed GONUTS page
  9. de Navascués J & Modolell J (2007) tailup, a LIM-HD gene, and Iro-C cooperate in Drosophila dorsal mesothorax specification. Development 134: 1779-88 PubMed GONUTS page
  10. Komiyama T & Luo L (2007) Intrinsic control of precise dendritic targeting by an ensemble of transcription factors. Curr Biol 17: 278-85 PubMed GONUTS page
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