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FB:trp

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) trp ( synonyms: 559, CG7875, Cosens-Manning mutant, DmTRP, INAD localization-B, TRP, Transient receptor potential protein, Trp, dTRP, dTrp, idl-B, transient photreceptor potential )
Protein Name(s) transient receptor potential,
External Links
FB FBgn0003861

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005218

intracellular ligand-gated calcium channel activity

FB:FBrf0159045
PMID:12647029[1]

NAS: Non-traceable Author Statement

F

From FB

GO:0005262

calcium channel activity

FB:FBrf0127201
PMID:10798390[2]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0005262

calcium channel activity

FB:FBrf0129697
PMID:10908615[3]

IMP: Inferred from Mutant Phenotype

F

From FB

GO:0005262

calcium channel activity

FB:FBrf0151691
PMID:11960680[4]

ISS: Inferred from Sequence or Structural Similarity

HGNC:12333

F

From FB

GO:0005262

calcium channel activity

FB:FBrf0151691
PMID:11960680[4]

ISS: Inferred from Sequence or Structural Similarity

MGI:MGI:109528

F

From FB

GO:0005515

protein binding

FB:FBrf0201375
PMID:17968007[5]

IPI: Inferred from Physical Interaction

FB:FBgn0259918

F

From FB

GO:0005516

calmodulin binding

FB:FBrf0123143
PMID:10611962[6]

TAS: Traceable Author Statement

F

From FB

GO:0005516

calmodulin binding

FB:FBrf0141625
PMID:11707492[7]

TAS: Traceable Author Statement

F

From FB

GO:0005516

calmodulin binding

FB:FBrf0151691
PMID:11960680[4]

TAS: Traceable Author Statement

F

From FB

GO:0005886

plasma membrane

FB:FBrf0210975

IDA: Inferred from Direct Assay

C

From FB

GO:0005887

integral to plasma membrane

FB:FBrf0123706

NAS: Non-traceable Author Statement

C

From FB

GO:0006816

calcium ion transport

FB:FBrf0127201
PMID:10798390[2]

ISS: Inferred from Sequence or Structural Similarity

P

From FB

GO:0006816

calcium ion transport

FB:FBrf0151691
PMID:11960680[4]

ISS: Inferred from Sequence or Structural Similarity

HGNC:12333

P

From FB

GO:0006816

calcium ion transport

FB:FBrf0151691
PMID:11960680[4]

ISS: Inferred from Sequence or Structural Similarity

MGI:MGI:109528

P

From FB

GO:0007602

phototransduction

FB:FBrf0123706

NAS: Non-traceable Author Statement

P

From FB

GO:0008086

light-activated voltage-gated calcium channel activity

FB:FBrf0123706

NAS: Non-traceable Author Statement

F

From FB

GO:0008087

light-activated voltage-gated calcium channel complex

FB:FBrf0123706

NAS: Non-traceable Author Statement

C

From FB

GO:0008104

protein localization

FB:FBrf0129943
PMID:10995445[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008355

olfactory learning

FB:FBrf0129943
PMID:10995445[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008377

light-induced release of internally sequestered calcium ion

FB:FBrf0108156
PMID:10326683[9]

IDA: Inferred from Direct Assay

P

From FB

GO:0009416

response to light stimulus

FB:FBrf0123143
PMID:10611962[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0009416

response to light stimulus

FB:FBrf0151691
PMID:11960680[4]

TAS: Traceable Author Statement

P

From FB

GO:0009416

response to light stimulus

FB:FBrf0159045
PMID:12647029[1]

TAS: Traceable Author Statement

P

From FB

GO:0015279

store-operated calcium channel activity

FB:FBrf0123143
PMID:10611962[6]

TAS: Traceable Author Statement

F

From FB

GO:0015279

store-operated calcium channel activity

FB:FBrf0151774
PMID:12386938[10]

NAS: Non-traceable Author Statement

F

From FB

GO:0015279

store-operated calcium channel activity

FB:FBrf0159045
PMID:12647029[1]

NAS: Non-traceable Author Statement

F

From FB

GO:0016021

integral to membrane

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR004729

C

From FB

GO:0016027

inaD signaling complex

FB:FBrf0129943
PMID:10995445[8]

IPI: Inferred from Physical Interaction

UniProtKB:Q24008

C

From FB

GO:0016027

inaD signaling complex

FB:FBrf0160593
PMID:12765677[11]

TAS: Traceable Author Statement

C

From FB

GO:0016028

rhabdomere

FB:FBrf0123143
PMID:10611962[6]

TAS: Traceable Author Statement

C

From FB

GO:0016028

rhabdomere

FB:FBrf0123253
PMID:10632594[12]

IDA: Inferred from Direct Assay

C

From FB

GO:0016028

rhabdomere

FB:FBrf0123706

NAS: Non-traceable Author Statement

C

From FB

GO:0016028

rhabdomere

FB:FBrf0147176
PMID:11931743[13]

IDA: Inferred from Direct Assay

C

From FB

GO:0016028

rhabdomere

FB:FBrf0190947
PMID:16301334[14]

IDA: Inferred from Direct Assay

C

From FB

GO:0019722

calcium-mediated signaling

FB:FBrf0123143
PMID:10611962[6]

TAS: Traceable Author Statement

P

From FB

GO:0030845

inhibition of phospholipase C activity involved in G-protein coupled receptor signaling pathway

FB:FBrf0187311
PMID:16005297[15]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0050908

detection of light stimulus involved in visual perception

FB:FBrf0050683
PMID:2482778[16]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0050962

detection of light stimulus involved in sensory perception

FB:FBrf0192668
PMID:16914683[17]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0070588

calcium ion transmembrane transport

FB:FBrf0129697
PMID:10908615[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0071454

cellular response to anoxia

FB:FBrf0129697
PMID:10908615[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0005614

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Voets T & Nilius B (2003) TRPs make sense. J Membr Biol 192: 1-8 PubMed GONUTS page
  2. 2.0 2.1 Littleton JT & Ganetzky B (2000) Ion channels and synaptic organization: analysis of the Drosophila genome. Neuron 26: 35-43 PubMed GONUTS page
  3. 3.0 3.1 3.2 Agam K et al. (2000) Metabolic stress reversibly activates the Drosophila light-sensitive channels TRP and TRPL in vivo. J Neurosci 20: 5748-55 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 4.5 Zitt C et al. (2002) The TRP family of cation channels: probing and advancing the concepts on receptor-activated calcium entry. Prog Neurobiol 66: 243-64 PubMed GONUTS page
  5. Cheng Y & Nash HA (2007) Drosophila TRP channels require a protein with a distinctive motif encoded by the inaF locus. Proc Natl Acad Sci U S A 104: 17730-4 PubMed GONUTS page
  6. 6.0 6.1 6.2 6.3 6.4 Montell C (1999) Visual transduction in Drosophila. Annu Rev Cell Dev Biol 15: 231-68 PubMed GONUTS page
  7. Hardie RC (2001) Phototransduction in Drosophila melanogaster. J Exp Biol 204: 3403-9 PubMed GONUTS page
  8. 8.0 8.1 8.2 Li HS & Montell C (2000) TRP and the PDZ protein, INAD, form the core complex required for retention of the signalplex in Drosophila photoreceptor cells. J Cell Biol 150: 1411-22 PubMed GONUTS page
  9. Cook B & Minke B (1999) TRP and calcium stores in Drosophila phototransduction. Cell Calcium 25: 161-71 PubMed GONUTS page
  10. Towers PR & Sattelle DB (2002) A Drosophila melanogaster cell line (S2) facilitates post-genome functional analysis of receptors and ion channels. Bioessays 24: 1066-73 PubMed GONUTS page
  11. Harteneck C (2003) Proteins modulating TRP channel function. Cell Calcium 33: 303-10 PubMed GONUTS page
  12. Yoon J et al. (2000) Novel mechanism of massive photoreceptor degeneration caused by mutations in the trp gene of Drosophila. J Neurosci 20: 649-59 PubMed GONUTS page
  13. Bähner M et al. (2002) Light-regulated subcellular translocation of Drosophila TRPL channels induces long-term adaptation and modifies the light-induced current. Neuron 34: 83-93 PubMed GONUTS page
  14. Wang T et al. (2005) Dissecting independent channel and scaffolding roles of the Drosophila transient receptor potential channel. J Cell Biol 171: 685-94 PubMed GONUTS page
  15. Gu Y et al. (2005) Mechanisms of light adaptation in Drosophila photoreceptors. Curr Biol 15: 1228-34 PubMed GONUTS page
  16. Wong F et al. (1989) Proper function of the Drosophila trp gene product during pupal development is important for normal visual transduction in the adult. Neuron 3: 81-94 PubMed GONUTS page
  17. Popescu DC et al. (2006) Scaffolding protein INAD regulates deactivation of vision by promoting phosphorylation of transient receptor potential by eye protein kinase C in Drosophila. J Neurosci 26: 8570-7 PubMed GONUTS page
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