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FB:trio

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) trio ( synonyms: 0368/10, 0959/14, 1372/03, 1386/06, BEST:LD36950, CG18214, CG9208, DTrio, M89, TRIO, Trio, UNC-73/Trio, l(3)036810, l(3)6D104, l(3)S036810, l(3)S095914, l(3)S137203, l(3)S138606, l(3)S(1372/3), l(3)S(1386/06), l(3)trio )
Protein Name(s) trio,
External Links
FB FBgn0024277

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005089

Rho guanyl-nucleotide exchange factor activity

FB:FBrf0124783

NAS: Non-traceable Author Statement

F

From FB

GO:0005089

Rho guanyl-nucleotide exchange factor activity

FB:FBrf0125543

NAS: Non-traceable Author Statement

F

From FB

GO:0005089

Rho guanyl-nucleotide exchange factor activity

FB:FBrf0128589
PMID:10847683[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0005089

Rho guanyl-nucleotide exchange factor activity

FB:FBrf0128589
PMID:10847683[1]

ISS: Inferred from Sequence or Structural Similarity

HGNC:12303

F

From FB

GO:0005543

phospholipid binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001849

F

From FB

GO:0005622

intracellular

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000219

C

From FB

GO:0005886

plasma membrane

FB:FBrf0128589
PMID:10847683[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0007266

Rho protein signal transduction

FB:FBrf0128589
PMID:10847683[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0007411

axon guidance

FB:FBrf0127003
PMID:10798395[2]

IGI: Inferred from Genetic Interaction

FB:FBgn0000464

P

From FB

GO:0007411

axon guidance

FB:FBrf0127003
PMID:10798395[2]

IGI: Inferred from Genetic Interaction

FB:FBgn0010333

P

From FB

GO:0007411

axon guidance

FB:FBrf0127003
PMID:10798395[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007411

axon guidance

FB:FBrf0127511
PMID:10798396[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0000017

P

From FB

GO:0007411

axon guidance

FB:FBrf0127511
PMID:10798396[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007411

axon guidance

FB:FBrf0128589
PMID:10847683[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007411

axon guidance

FB:FBrf0136755
PMID:11493634[4]

TAS: Traceable Author Statement

P

From FB

GO:0007412

axon target recognition

FB:FBrf0212351
PMID:21084592[5]

IGI: Inferred from Genetic Interaction

FB:FBgn0046704

P

From FB

GO:0007417

central nervous system development

FB:FBrf0127003
PMID:10798395[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007417

central nervous system development

FB:FBrf0127511
PMID:10798396[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0000017

P

From FB

GO:0007417

central nervous system development

FB:FBrf0127511
PMID:10798396[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007417

central nervous system development

FB:FBrf0155968
PMID:12471442[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007422

peripheral nervous system development

FB:FBrf0127003
PMID:10798395[2]

IGI: Inferred from Genetic Interaction

FB:FBgn0000464

P

From FB

GO:0007422

peripheral nervous system development

FB:FBrf0127003
PMID:10798395[2]

IGI: Inferred from Genetic Interaction

FB:FBgn0010333

P

From FB

GO:0007422

peripheral nervous system development

FB:FBrf0127003
PMID:10798395[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016319

mushroom body development

FB:FBrf0202859
PMID:18267091[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030036

actin cytoskeleton organization

FB:FBrf0127511
PMID:10798396[3]

IEP: Inferred from Expression Pattern

P

From FB

GO:0030036

actin cytoskeleton organization

FB:FBrf0128589
PMID:10847683[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0035023

regulation of Rho protein signal transduction

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000219

P

From FB

GO:0045887

positive regulation of synaptic growth at neuromuscular junction

FB:FBrf0210920
PMID:20510858[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0046331

lateral inhibition

FB:FBrf0214518

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048676

axon extension involved in development

FB:FBrf0210319
PMID:18516287[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0050770

regulation of axonogenesis

FB:FBrf0180582
PMID:15572110[10]

IGI: Inferred from Genetic Interaction

FB:FBgn0041203

P

From FB

GO:0071772

response to BMP stimulus

FB:FBrf0210920
PMID:20510858[8]

IGI: Inferred from Genetic Interaction

FB:FBgn0011648

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 Newsome TP et al. (2000) Trio combines with dock to regulate Pak activity during photoreceptor axon pathfinding in Drosophila. Cell 101: 283-94 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Bateman J et al. (2000) The guanine nucleotide exchange factor trio mediates axonal development in the Drosophila embryo. Neuron 26: 93-106 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 Liebl EC et al. (2000) Dosage-sensitive, reciprocal genetic interactions between the Abl tyrosine kinase and the putative GEF trio reveal trio's role in axon pathfinding. Neuron 26: 107-18 PubMed GONUTS page
  4. Bateman J & Van Vactor D (2001) The Trio family of guanine-nucleotide-exchange factors: regulators of axon guidance. J Cell Sci 114: 1973-80 PubMed GONUTS page
  5. Astigarraga S et al. (2010) Three Drosophila liprins interact to control synapse formation. J Neurosci 30: 15358-68 PubMed GONUTS page
  6. Saito M et al. (2002) Genetic analyses of essential genes in cytological region 61D1-2 to 61F1-2 of Drosophila melanogaster. Mol Genet Genomics 268: 446-54 PubMed GONUTS page
  7. Schuldiner O et al. (2008) piggyBac-based mosaic screen identifies a postmitotic function for cohesin in regulating developmental axon pruning. Dev Cell 14: 227-38 PubMed GONUTS page
  8. 8.0 8.1 Ball RW et al. (2010) Retrograde BMP signaling controls synaptic growth at the NMJ by regulating trio expression in motor neurons. Neuron 66: 536-49 PubMed GONUTS page
  9. Berger J et al. (2008) Systematic identification of genes that regulate neuronal wiring in the Drosophila visual system. PLoS Genet 4: e1000085 PubMed GONUTS page
  10. Ng J & Luo L (2004) Rho GTPases regulate axon growth through convergent and divergent signaling pathways. Neuron 44: 779-93 PubMed GONUTS page
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