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FB:trh

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) trh ( synonyms: 3.1, BP1081, CG13885, CG42865, CG6883, DMU42699, HDC07747, TRH, Trachealess, Trh, bHLHe13, l(3)10512 )
Protein Name(s) trachealess,
External Links
FB FBgn0262139

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000981

sequence-specific DNA binding RNA polymerase II transcription factor activity

FB:FBrf0085269
PMID:8557189[1]

ISS: Inferred from Sequence or Structural Similarity

FB:FBgn0004666

F

From FB

GO:0000981

sequence-specific DNA binding RNA polymerase II transcription factor activity

FB:FBrf0085269
PMID:8557189[1]

ISS: Inferred from Sequence or Structural Similarity

HGNC:4910

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0124266

NAS: Non-traceable Author Statement

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0167264
PMID:14570584[2]

TAS: Traceable Author Statement

F

From FB

GO:0004871

signal transducer activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000014

F

From FB

GO:0005634

nucleus

FB:FBrf0085269
PMID:8557189[1]

ISS: Inferred from Sequence or Structural Similarity

FB:FBgn0004666

C

From FB

GO:0005634

nucleus

FB:FBrf0085269
PMID:8557189[1]

ISS: Inferred from Sequence or Structural Similarity

HGNC:4910

C

From FB

GO:0005634

nucleus

FB:FBrf0086149
PMID:8557198[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0005634

nucleus

FB:FBrf0124266

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0167264
PMID:14570584[2]

TAS: Traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0214024
PMID:21693579[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0006355

regulation of transcription, DNA-dependent

FB:FBrf0086149
PMID:8557198[3]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P05709

P

From FB

GO:0006357

regulation of transcription from RNA polymerase II promoter

FB:FBrf0124266

NAS: Non-traceable Author Statement

P

From FB

GO:0007165

signal transduction

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000014
InterPro:IPR001610

P

From FB

GO:0007424

open tracheal system development

FB:FBrf0086149
PMID:8557198[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007424

open tracheal system development

FB:FBrf0124266

NAS: Non-traceable Author Statement

P

From FB

GO:0007424

open tracheal system development

FB:FBrf0139594
PMID:11598957[5]

TAS: Traceable Author Statement

P

From FB

GO:0007425

epithelial cell fate determination, open tracheal system

FB:FBrf0125237
PMID:10684581[6]

TAS: Traceable Author Statement

P

From FB

GO:0007425

epithelial cell fate determination, open tracheal system

FB:FBrf0131240
PMID:11063940[7]

TAS: Traceable Author Statement

P

From FB

GO:0007425

epithelial cell fate determination, open tracheal system

FB:FBrf0141466
PMID:11740943[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007425

epithelial cell fate determination, open tracheal system

FB:FBrf0160886
PMID:12885551[9]

TAS: Traceable Author Statement

P

From FB

GO:0007425

epithelial cell fate determination, open tracheal system

FB:FBrf0167264
PMID:14570584[2]

TAS: Traceable Author Statement

P

From FB

GO:0007431

salivary gland development

FB:FBrf0086149
PMID:8557198[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007431

salivary gland development

FB:FBrf0124266

NAS: Non-traceable Author Statement

P

From FB

GO:0007431

salivary gland development

FB:FBrf0159337
PMID:12742168[10]

NAS: Non-traceable Author Statement

P

From FB

GO:0007435

salivary gland morphogenesis

FB:FBrf0139594
PMID:11598957[5]

TAS: Traceable Author Statement

P

From FB

GO:0007435

salivary gland morphogenesis

FB:FBrf0160584
PMID:12798300[11]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007443

Malpighian tubule morphogenesis

FB:FBrf0111391
PMID:10502111[12]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035277

spiracle morphogenesis, open tracheal system

FB:FBrf0111388
PMID:10491268[13]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0043565

sequence-specific DNA binding

FB:FBrf0202405
PMID:17652079[14]

IDA: Inferred from Direct Assay

F

From FB

GO:0046331

lateral inhibition

FB:FBrf0214518

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0046982

protein heterodimerization activity

FB:FBrf0099730
PMID:9409674[15]

IPI: Inferred from Physical Interaction

FB:FBgn0015014

F

From FB

GO:0046982

protein heterodimerization activity

FB:FBrf0125237
PMID:10684581[6]

TAS: Traceable Author Statement

F

From FB

GO:0046982

protein heterodimerization activity

FB:FBrf0167264
PMID:14570584[2]

TAS: Traceable Author Statement

F

From FB

GO:0048813

dendrite morphogenesis

FB:FBrf0190556
PMID:16547170[16]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0072175

epithelial tube formation

FB:FBrf0085269
PMID:8557189[1]

IMP: Inferred from Mutant Phenotype

P

From FB

contributes_to

GO:0001077

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription

FB:FBrf0099730
PMID:9409674[15]

IPI: Inferred from Physical Interaction

FB:FBgn0015014

F

From FB

contributes_to

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0202405
PMID:17652079[14]

IPI: Inferred from Physical Interaction

FB:FBgn0015014

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Isaac DD & Andrew DJ (1996) Tubulogenesis in Drosophila: a requirement for the trachealess gene product. Genes Dev 10: 103-17 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Ghabrial A et al. (2003) Branching morphogenesis of the Drosophila tracheal system. Annu Rev Cell Dev Biol 19: 623-47 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Wilk R et al. (1996) trachealess encodes a bHLH-PAS protein that is an inducer of tracheal cell fates in Drosophila. Genes Dev 10: 93-102 PubMed GONUTS page
  4. Araújo SJ & Casanova J (2011) Sequoia establishes tip-cell number in Drosophila trachea by regulating FGF levels. J Cell Sci 124: 2335-40 PubMed GONUTS page
  5. 5.0 5.1 Bradley PL et al. (2001) Organ formation in Drosophila: specification and morphogenesis of the salivary gland. Bioessays 23: 901-11 PubMed GONUTS page
  6. 6.0 6.1 Zelzer E & Shilo BZ (2000) Cell fate choices in Drosophila tracheal morphogenesis. Bioessays 22: 219-26 PubMed GONUTS page
  7. Affolter M & Shilo BZ (2000) Genetic control of branching morphogenesis during Drosophila tracheal development. Curr Opin Cell Biol 12: 731-5 PubMed GONUTS page
  8. Jin J et al. (2001) Regulation of Drosophila tracheal system development by protein kinase B. Dev Cell 1: 817-27 PubMed GONUTS page
  9. Ribeiro C et al. (2003) Signaling systems, guided cell migration, and organogenesis: insights from genetic studies in Drosophila. Dev Biol 260: 1-8 PubMed GONUTS page
  10. Abrams EW et al. (2003) Constructing an organ: the Drosophila salivary gland as a model for tube formation. Trends Cell Biol 13: 247-54 PubMed GONUTS page
  11. Haberman AS et al. (2003) Specification of cell fates within the salivary gland primordium. Dev Biol 258: 443-53 PubMed GONUTS page
  12. Jack J & Myette G (1999) Mutations that alter the morphology of the malpighian tubules in Drosophila. Dev Genes Evol 209: 546-54 PubMed GONUTS page
  13. Hu N & Castelli-Gair J (1999) Study of the posterior spiracles of Drosophila as a model to understand the genetic and cellular mechanisms controlling morphogenesis. Dev Biol 214: 197-210 PubMed GONUTS page
  14. 14.0 14.1 Jiang L & Crews ST (2007) Transcriptional specificity of Drosophila dysfusion and the control of tracheal fusion cell gene expression. J Biol Chem 282: 28659-68 PubMed GONUTS page
  15. 15.0 15.1 Sonnenfeld M et al. (1997) The Drosophila tango gene encodes a bHLH-PAS protein that is orthologous to mammalian Arnt and controls CNS midline and tracheal development. Development 124: 4571-82 PubMed GONUTS page
  16. Parrish JZ et al. (2006) Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. Genes Dev 20: 820-35 PubMed GONUTS page
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