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FB:tok

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) tok ( synonyms: CG6863, CT21251, TOK, Tlr, Tlr-1, Tok, Tolkin, Tolloid-related, piranha, tld-related-1, tldr-1, tldr1, tlr, tlr-1, tlr1, tolloid-related, tolloid-related 1 )
Protein Name(s) tolkin,
External Links
FB FBgn0004885

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004222

metalloendopeptidase activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P13497

F

From FB

GO:0005509

calcium ion binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001881
InterPro:IPR018097

F

From FB

GO:0006508

proteolysis

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001506
InterPro:IPR006026

P

From FB

GO:0007411

axon guidance

FB:FBrf0194328
PMID:17119021[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007415

defasciculation of motor neuron axon

FB:FBrf0193012
PMID:16971470[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008045

motor axon guidance

FB:FBrf0193012
PMID:16971470[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008270

zinc ion binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR006026

F

From FB

GO:0008586

imaginal disc-derived wing vein morphogenesis

FB:FBrf0187482
PMID:15872004[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0010629

negative regulation of gene expression

FB:FBrf0193889
PMID:16780828[4]

IDA: Inferred from Direct Assay

P

From FB

GO:0016485

protein processing

FB:FBrf0194328
PMID:17119021[1]

IDA: Inferred from Direct Assay

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Serpe M & O'Connor MB (2006) The metalloprotease tolloid-related and its TGF-beta-like substrate Dawdle regulate Drosophila motoneuron axon guidance. Development 133: 4969-79 PubMed GONUTS page
  2. 2.0 2.1 Meyer F & Aberle H (2006) At the next stop sign turn right: the metalloprotease Tolloid-related 1 controls defasciculation of motor axons in Drosophila. Development 133: 4035-44 PubMed GONUTS page
  3. Serpe M et al. (2005) Matching catalytic activity to developmental function: tolloid-related processes Sog in order to help specify the posterior crossvein in the Drosophila wing. Development 132: 2645-56 PubMed GONUTS page
  4. Anderson J et al. (2006) Regulation of the retinal determination gene dachshund in the embryonic head and developing eye of Drosophila. Dev Biol 297: 536-49 PubMed GONUTS page
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